HL-A ANTIGENS AND DIABETES MELLITUS
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Early twin studies indicated >90% concordance of diabetes in those diagnosed at older ages (type 2 diabetes) and approximately 50% concordance of diabetes occurring in children and young adults (type 1 diabetes).
“A theme of early twin studies indicated >90% concordance of diabetes in those diagnosed at older ages (that is, type 2 diabetes) and approximately 50% concordance of diabetes occurring in children and young adults (that is, type 1 diabetes)8,46,47.”
From 100 years of insulin: celebrating the past, present and future of diabetes therapy (2021) · cites this paper as [8]
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Noble, J. A., & Erlich, H. A. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a007732 · Cited by 335 · see citing works
The Inherited Basis of Diabetes Mellitus: Implications for the Genetic Analysis of Complex Traits
Florez, J. C., Hirschhorn, J., & Altshuler, D. (2003) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.4.070802.110436 · Cited by 329 · see citing works
100 years of insulin: celebrating the past, present and future of diabetes therapy
Sims, E. K., Carr, A. L. J., Oram, R. A., DiMeglio, L. A., & Evans-Molina, C. (2021) · Nature Medicine · doi:10.1038/s41591-021-01418-2 · Cited by 270 · see citing works
Immunogenetics of type 1 diabetes: a comprehensive review
Noble, J. A. (2015) · Journal of Autoimmunity · doi:10.1016/j.jaut.2015.07.014 · Cited by 227 · see citing works
Redondo, M. J., Steck, A. K., & Pugliese, A. (2018) · Pediatric Diabetes · doi:10.1111/pedi.12597 · Cited by 216 · see citing works
- Authors
- Cudworth, A. G., & Woodrow, J. C.
- Affiliations
- University of Liverpool (GB)
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1974-11
- Volume
- 304
- Issue
- 7889
- Pages
- 1153
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2090529817
- Cited by
- 141
- References
- 0
- Citations by year
- 2026: 1 · 2024: 6 · 2023: 3 · 2022: 5 · 2021: 5 · 2020: 4 · 2019: 2 · 2018: 5 · 2017: 6 · 2015: 3 · 2014: 2 · 2013: 1 · 2012: 4
- FWCI
- 10.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Health Sciences › Medicine › Transplantation › Renal Transplantation Outcomes and Treatments
- Keywords
- HLA antigens, diabetes mellitus, HLA-DQ, HLA-DR, HLA-B8, HLA class II, genetic susceptibility
- MeSH terms
- Adolescent, Adult, Age Factors, Coxsackievirus Infections, Diabetes Mellitus, Diabetes Mellitus, Type 1, Genes, Glucose Tolerance Test, Haploidy, Histocompatibility Antigens, HLA Antigens, Humans, Pedigree
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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