The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
FURTHER EXPERIENCE OF VITAMIN SUPPLEMENTATION FOR PREVENTION OF NEURAL TUBE DEFECT RECURRENCES
Abstract
In accordance with a previous protocol, a second cohort of 254 mothers with a history of previous neural tube defect (NTD) births was before a subsequent conception and continued until the time of the second missed menstrual period. There were 2 NTD recurrences (0.9% of 234 infants/fetuses examined), which is significantly fewer than the 11 NTD recurrences (5.1% of 215 infants/fetuses examined) born to 219 unsupplemented (US) mothers in the same centres over the same period. When the data for the two cohorts were combined, the overall recurrence rates were 0.7% for 454 fully supplemented (FS) mothers and 4.7% for 519 US mothers. The recurrence rates after 1 previous NTD were 0.5% for FS and 4.2% for US mothers: after 2 or more previous NTDs, 2.3% for FS and 9.6% for US. There were no recurrences among the offspring of a further 114 mothers whose duration of supplementation fell short of the full regimen (partially supplemented, PS).
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“the teratogenic effects of a low folate lead to NTDs such as spina bifida and anencephaly”
From The evolution of human skin pigmentation: A changing medley of vitamins, genetic variability, and UV radiation during human expansion (2023) · cites this paper as Smithells et al., 1983
Citations
Cites
Apparent prevention of neural tube defects by periconceptional vitamin supplementation.
Smithells, R. W., Sheppard, S., Schorah, C. J., Seller, M. J., Nevin, N. C., Harris, R., Read, A. P., & Fielding, D. W. (1981) · Archives of Disease in Childhood · doi:10.1136/adc.56.12.911 · Cited by 385
Self-citationSpina bifida and anencephaly: miscarriage as possible cause.
Clarke, C., Hobson, D., McKendrick, O., et al. (1975) · BMJ · doi:10.1136/bmj.4.5999.743 · Cited by 71
Influence of Social Class on the Risk of Recurrence of Anencephalus and Spina Bifida
Nevin, N. C., Johnston, W. P., & Merrett, J. D. (1981) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1981.tb02437.x · Cited by 48
Self-citation
Cited by
Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
(1991) · The Lancet · doi:10.1016/0140-6736(91)90133-a · Cited by 3,472
Prevention of neural tube defects: Results of the Medical Research Council vitamin study
Wald, N., Sneddon, J., Densem, J., Frost, C., & Stone, R. (1992) · International Journal of Gynecology & Obstetrics · doi:10.1016/0020-7292(92)90076-u · Cited by 2,364
Folic Acid: Nutritional Biochemistry, Molecular Biology, and Role in Disease Processes
Lucock, M. (2000) · Molecular Genetics and Metabolism · doi:10.1006/mgme.2000.3027 · Cited by 815
Neural tube defects and folate: case far from closed
Blom, H. J., Shaw, G. M., den Heijer, M., & Finnell, R. H. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1986 · Cited by 562
Tamura, T., & Picciano, M. F. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.5.993 · Cited by 379
Metadata
- Authors
- Smithells, R. W., Seller, M. J., Harris, R., Fielding, D. W., Schorah, C. J., Nevin, N. C., Sheppard, S., Read, A. P., Walker, S., & Wild, J.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1983-05
- Volume
- 321
- Issue
- 8332
- Pages
- 1027-1031
- ISSN
- 0140-6736
- Cited by
- 383
- References
- 3
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: FURTHER EXPERIENCE OF VITAMIN SUPPLEMENTATION FOR PREVENTION OF NEURAL TUBE DEFECT RECURRENCES. https://app.cochat.ai/papers/10.1016/s0140-6736(83)92654-5
- The paper
- Smithells, R. W., Seller, M. J., Harris, R., Fielding, D. W., Schorah, C. J., Nevin, N. C., Sheppard, S., Read, A. P., Walker, S., & Wild, J. (1983). FURTHER EXPERIENCE OF VITAMIN SUPPLEMENTATION FOR PREVENTION OF NEURAL TUBE DEFECT RECURRENCES. The Lancet. https://doi.org/10.1016/s0140-6736(83)92654-5
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.