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Cited by 780Alcohol Consumption and Health EffectsSubstance Abuse Treatment and OutcomesCoffee research and impacts

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

ALCOHOL AND MORTALITY IN BRITISH MEN: EXPLAINING THE U-SHAPED CURVE

Shaper, A.G., Wannamethee, Goya, Walker, Mary·1988·The Lancet
DOI 10.1016/s0140-6736(88)92890-5
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Abstract

In a prospective study of 7735 middle-aged 7 British men, 504 of whom died in a follow-up period of 7.5 years, there was a U-shaped relationship between alcohol intake and total mortality and an inverse relationship with cardiovascular mortality, even after adjustment for age, cigarette smoking, and social class. These mortality patterns were seen in all smoking categories (with ex-smoking non-drinkers having the highest mortality) and were observed in manual but not in non-manual workers. The alcohol-mortality relationships (total and cardiovascular) were present only in men with cardiovascular or cardiovascular-related doctor-diagnosed illnesses at initial examination. The data suggest that the observed alcohol-mortality relationships are produced by pre-existing disease and by the movement of men with such disease into non-drinking or occasional-drinking categories. The concept of a "protective" effect of drinking on mortality, ignoring the dynamic relationship between ill-health and drinking behaviour, is likely to be ill founded.

Overview

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Registry

Crossref · 10.1016/s0140-6736(88)92890-5

Cites

32 of 32 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 3

  1. Grindall, 1987, Exploding the myth: the truth about alcohol misuse, Morning Advertiser
  2. Wannamethee, 1988, Changes m drinking habits in middle-aged British men, J R Coll Gen Pract, 38, 440
  3. 1987, Lancet, n, 1249

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Metadata

Authors
Shaper, A. G., Wannamethee, G., & Walker, M.
Affiliations
The Royal Free Hospital (GB)
ORCID
Walker, Mary
Venue
The Lancet
Publisher
Elsevier BV
Published
1988-12
Volume
332
Issue
8623
Pages
1267-1273
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
DOI
10.1016/s0140-6736(88)92890-5
OpenAlex
W2048919469
Cited by
780
References
32
Citations by year
2026: 19 · 2025: 10 · 2024: 20 · 2023: 14 · 2022: 21 · 2021: 22 · 2020: 22 · 2019: 31 · 2018: 27 · 2017: 19 · 2016: 33 · 2015: 20 · 2014: 28 · 2013: 26 · 2012: 19
FWCI
15.94
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
Keywords
alcohol consumption, mortality, U-shaped curve, cardiovascular mortality, all-cause mortality, middle-aged men, smoking, social class, blue-collar workers, pre-existing disease, drinking behavior
MeSH terms
Alcohol Drinking, Alcoholism, Cardiovascular Diseases, Follow-Up Studies, United Kingdom, Humans, Male, Middle Aged, Risk Factors, Smoking, Social Class

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