Bias: Table 1
Open accessAbstract
The concept of bias is the lack of internal validity or incorrect assessment of the association between an exposure and an effect in the target population in which the statistic estimated has an expectation that does not equal the true value. Biases can be classified by the research stage in which they occur or by the direction of change in a estimate. The most important biases are those produced in the definition and selection of the study population, data collection, and the association between different determinants of an effect in the population. A definition of the most common biases occurring in these stages is given.
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Time to diagnosis was approximately 1 year longer in the never-treated population, which could indicate a healthy survivor effect.
“This is especially important since time to diagnosis was ∼1 year longer in the never-treated population, which could indicate a “healthy survivor effect” [28].”
From Survival and course of lung function in the presence or absence of antifibrotic treatment in patients with idiopathic pulmonary fibrosis: long-term results of the INSIGHTS-IPF registry (2020) · cites this paper as [28]
Section 1.1 describes selective survival and survivor treatment selection bias, supporting the possibility of a survivor-related effect. It does not report a never-treated population or an approximately one-year difference in time to diagnosis; searches for those details found no matching passage. Page numbers were not available in our copy. (LLM, conf=0.85)
Experimental — accuracy not yet measuredA recent simulation study by Nelson et al. showed that first-generation methylation ageing clocks do worse than random chance at identifying causal ageing loci due to cohort selection effects in cross-sectional ageing cohorts.
“A recent simulation study by Nelson et al.168 bolsters the rationale for training these composite models, showing that first-generation methylation ageing clocks do worse than random chance at identifying causal ageing loci due to cohort selection effects that occur in cross-sectional ageing cohorts169,170.”
From Measuring biological age using omics data (2022) · cites this paper as [169]
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- Authors
- Delgado-Rodríguez, M., & Llorca, J.
- Affiliations
- Universidad de Cantabria (ES)
- ORCID
- Llorca, J
- Venue
- Journal of Epidemiology and Community Health
- Publisher
- BMJ
- Published
- 2004-07-13
- Volume
- 58
- Issue
- 8
- Pages
- 635-641
- ISSN
- 0141-7681 (ISSN-L)
- 0143-005X
- 1470-2738
- OpenAlex
- W4248217291
- Cited by
- 1,064
- References
- 71
- Citations by year
- 2026: 44 · 2025: 59 · 2024: 92 · 2023: 95 · 2022: 92 · 2021: 84 · 2020: 85 · 2019: 57 · 2018: 54 · 2017: 63 · 2016: 75 · 2015: 68 · 2014: 44 · 2013: 24 · 2012: 14
- FWCI
- 13.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Epidemiology & Community Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
- Keywords
- bias, internal validity, population selection, data collection errors, confounding, measurement error
- MeSH terms
- Data Collection, Epidemiologic Methods, Humans, Terminology as Topic, Research Design, Reproducibility of Results, Bias, Selection Bias, Confounding Factors, Epidemiologic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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