The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
ALCOHOL AND MORTALITY IN BRITISH MEN: EXPLAINING THE U-SHAPED CURVE
Abstract
In a prospective study of 7735 middle-aged 7 British men, 504 of whom died in a follow-up period of 7.5 years, there was a U-shaped relationship between alcohol intake and total mortality and an inverse relationship with cardiovascular mortality, even after adjustment for age, cigarette smoking, and social class. These mortality patterns were seen in all smoking categories (with ex-smoking non-drinkers having the highest mortality) and were observed in manual but not in non-manual workers. The alcohol-mortality relationships (total and cardiovascular) were present only in men with cardiovascular or cardiovascular-related doctor-diagnosed illnesses at initial examination. The data suggest that the observed alcohol-mortality relationships are produced by pre-existing disease and by the movement of men with such disease into non-drinking or occasional-drinking categories. The concept of a "protective" effect of drinking on mortality, ignoring the dynamic relationship between ill-health and drinking behaviour, is likely to be ill founded.
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“using last‐year abstention may bias results by introducing sick‐quitters 348”
From The relationship between different dimensions of alcohol use and the burden of disease—an update (2017) · cites this paper as [348]
Citations
Cites
The analysis of case-control studies
Breslow, N. E., & Day, N. E. (1980) · International Agency for Research on Cancer eBooks · Cited by 2,415
British Regional Heart Study: cardiovascular risk factors in middle-aged men in 24 towns.
Shaper, A. G., Pocock, S., Walker, M., Cohen, N. M., Wale, C. J., & Thomson, A. G. (1981) · BMJ · doi:10.1136/bmj.283.6285.179 · Cited by 526
Self-citationCoffee, Alcohol and Risk of Coronary Heart Disease among Japanese Men Living in Hawaii
Yano, K., Rhoads, G. G., & Kagan, A. (1977) · New England Journal of Medicine · doi:10.1056/nejm197708252970801 · Cited by 524
ALCOHOL AND MORTALITY: A U-SHAPED CURVE
Marmot, M. G., Shipley, M. J., Rose, G., & Thomas, B. J. (1981) · The Lancet · doi:10.1016/s0140-6736(81)92032-8 · Cited by 464
Alcohol and Coronary Heart Disease
Marmot, M. G. (1984) · International Journal of Epidemiology · doi:10.1093/ije/13.2.160 · Cited by 360
CORONARY HEART DISEASE MORTALITY AND ALCOHOL CONSUMPTION IN FRAMINGHAM
Friedman, L. A., & Kimball, A. W. (1986) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114418 · Cited by 348
Klatsky, A. L., FRIEDMAN, G. D., & SIEGELAUB, A. B. (1981) · Annals of Internal Medicine · doi:10.7326/0003-4819-95-2-139 · Cited by 347
Moderate Alcohol Consumption and Coronary Artery Disease
Moore, R. D., & Pearson, T. A. (1986) · Medicine · doi:10.1097/00005792-198607000-00004 · Cited by 308
Dyer, A. R., Stamler, J., Paul, O., Berkson, D. M., Lepper, M. H., McKean, H. E., Shekelle, R. B., Lindberg, H. A., & Garside, D. (1977) · Circulation · doi:10.1161/01.cir.56.6.1067 · Cited by 305
KOZARAREVIC, D. (1980) · The Lancet · doi:10.1016/s0140-6736(80)91116-2 · Cited by 238
Research works printed but not linked: 3
- Grindall, 1987, Exploding the myth: the truth about alcohol misuse, Morning Advertiser
- Wannamethee, 1988, Changes m drinking habits in middle-aged British men, J R Coll Gen Pract, 38, 440
- 1987, Lancet, n, 1249
Cited by
Sorted by citations
Alcohol consumption and mortality among middle-aged and elderly U.S. adults
Thun, M. J., Peto, R., Lopez, A. D., Monaco, J. H., Henley, S. J., Heath, C. W., & Doll, R. (1997) · New England Journal of Medicine · doi:10.1056/nejm199712113372401 · Cited by 1,313
The relationship between different dimensions of alcohol use and the burden of disease—an update
Rehm, J., Gmel, G. E., Gmel, G., Hasan, O. S. M., Imtiaz, S., Popova, S., Probst, C., Roerecke, M., Room, R., Samokhvalov, A. V., et al. (2017) · Addiction · doi:10.1111/add.13757 · Cited by 1,204
Prospective study of alcohol consumption and risk of coronary disease in men.
Rimm, E. B., Giovannucci, E. L., Willett, W. C., Colditz, G. A., Ascherio, A., Rosner, B., & Stampfer, M. J. (1991) · The Lancet · doi:10.1016/0140-6736(91)90542-w · Cited by 1,239
The relation between different dimensions of alcohol consumption and burden of disease: an overview
Rehm, J., Baliunas, D., Borges, G. L. G., Graham, K., Irving, H., Kehoe, T., Parry, C. D., Patra, J., Popova, S., Poznyak, V., et al. (2010) · Addiction · doi:10.1111/j.1360-0443.2010.02899.x · Cited by 1,174
Delgado-Rodríguez, M., & Llorca, J. (2004) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2003.008466 · Cited by 1,064
Metadata
- Authors
- Shaper, A. G., Wannamethee, G., & Walker, M.
- Affiliations
- The Royal Free Hospital (GB)
- ORCID
- Walker, Mary
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1988-12
- Volume
- 332
- Issue
- 8623
- Pages
- 1267-1273
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2048919469
- Cited by
- 780
- References
- 32
- Citations by year
- 2026: 19 · 2025: 10 · 2024: 20 · 2023: 14 · 2022: 21 · 2021: 22 · 2020: 22 · 2019: 31 · 2018: 27 · 2017: 19 · 2016: 33 · 2015: 20 · 2014: 28 · 2013: 26 · 2012: 19
- FWCI
- 15.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
- Keywords
- alcohol consumption, mortality, U-shaped curve, cardiovascular mortality, all-cause mortality, middle-aged men, smoking, social class, blue-collar workers, pre-existing disease, drinking behavior
- MeSH terms
- Alcohol Drinking, Alcoholism, Cardiovascular Diseases, Follow-Up Studies, United Kingdom, Humans, Male, Middle Aged, Risk Factors, Smoking, Social Class
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