Horizontal transmission of hepatitis B virus.
Abstract
Meta-analysis of seroprevalence surveys shows that horizontal transmission of hepatitis B virus (ie, that occurring without apparent parenteral, sexual, or perinatal exposure) is common in areas endemic for the virus. It occurs especially in pre-adolescent children. In developed countries, where endemicity of hepatitis B virus is low, horizontal transmission (probably via saliva or open wounds) may occur in households with a persistent carrier, but it is less efficient a means of infection than is sexual or perinatal transmission. Horizontal transmission also seems possible in pre-school day-care centres in developed countries, despite the small numbers of carriers in such places.
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Studies have demonstrated other modes of HBV transmission, including premastication and lapses in health care infection control procedures, as less common sources of transmission.
“In addition, studies have demonstrated other modes of HBV transmission, including premastication and lapses in health care infection control procedures, as less common sources of transmission (1314–1317).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1315]
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Sexually Transmitted Infections Treatment Guidelines, 2021
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Self-citation
- Authors
- Gray Davis, L., Weber, D., & Lemon, S.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1989-04
- Volume
- 333
- Issue
- 8643
- Pages
- 889-893
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1971902359
- Cited by
- 208
- References
- 50
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 7 · 2020: 2 · 2019: 4 · 2018: 2 · 2017: 3 · 2016: 6 · 2015: 7 · 2014: 8 · 2013: 8 · 2012: 15
- FWCI
- 8.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01hl037974-05)
- National Heart, Lung, and Blood Institute (R01-HL-37974)
- Topics
- Health Sciences › Medicine › Epidemiology › Hepatitis B Virus Studies
- Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
- Health Sciences › Medicine › Hepatology › Hepatitis Viruses Studies and Epidemiology
- Keywords
- hepatitis B virus, horizontal transmission, household transmission, daycare centers, preadolescents, seroprevalence, saliva transmission, endemicity, sexual transmission, perinatal transmission
- MeSH terms
- Adolescent, Adult, Age Factors, Carrier State, Child, Child, Preschool, DNA, Viral, Family Health, Hepatitis B, Hepatitis B Antibodies, Hepatitis B e Antigens, Hepatitis B Surface Antigens, Hepatitis B virus, Hepatitis, Chronic, Humans, Infant, Infant, Newborn, Middle Aged, Risk Factors, Saliva, Schools, Virus Replication, Global Health, Meta-Analysis as Topic
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