Cited by 623Clinical Nutrition and GastroenterologySepsis Diagnosis and TreatmentNosocomial Infections in ICU

The DOI matches its Crossref record; 31 of the 32 references it cites were found in a registry or an index.

Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma

Houdijk, Alexander PJ, Rijnsburger, Emmy R, Jansen, Jaap, Wesdorp, Robert IC, Weiss, Jeffery K, McCamish, Mark A, Teerlink, Tom, Meuwissen, Stephan GM, Haarman, Henk J Th M, Thijs, Lambertus G, van Leeuwen, Paul AM·1998·The Lancet

DOI 10.1016/s0140-6736(98)02007-8

Open this paper in CoChat — free account

Abstract

Background Infections are an important cause of morbidity and mortality in patients with multiple trauma. Studies in both animals and human beings have suggested that glutamine-enriched nutrition decreases the number of infections. Methods Patients with multiple trauma with an expected survival of more than 48 h, and who had an Injury Severity Score of 20 or more, were randomly allocated glutamine supplemented enteral nutrition or a balanced, isonitrogenous, isocaloric enteral-feeding regimen along with usual care. Each patient was assessed every 8 h for infection, the primary endpoint. Data were analysed both per protocol, which included enteral feeding for at least 5 days, and by intention to treat. Findings 72 patients were enrolled and 60 received enteral feeding (29 glutamine-supplemented) for at least 5 days. Five (17%) of 29 patients in the glutamine-supplemented group had pneumonia compared with 14 (45%) of 31 patients in the control group (p<0.02). Bacteraemia occurred in two (7%) patients in glutamine group and 13 (42%) in the control group (p<0.005). One patient in the glutamine group had sepsis compared with eight (26%) patients in the control group (p<0.02). Interpretation There was a low frequency of pneumonia, sepsis, and bacteraemia in patients with multiple trauma who received glutamine-supplemented enteral nutrition. Larger studies are needed to investigate whether glutamine-supplemented enteral nutrition reduces mortality.

Integrity signals

Registry

Crossref · 10.1016/s0140-6736(98)02007-8

Cites

31 of 31 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Prediction of Creatinine Clearance from Serum Creatinine
Cockcroft, D. W., & Gault, H. (2008) · The Nephron journals/Nephron journals · doi:10.1159/000180580 · Cited by 15,291
The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care.
Baker, S. P., O’Neill, B., Haddon, W. F., & Long, W. B. (1974) · PubMed · Cited by 7,946
THE INJURY SEVERITY SCORE
Baker, S. P., O’Neill, B., Haddon, W. F., & Long, W. B. (1974) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-197403000-00001 · Cited by 7,326
A biometric study of basal metabolism in man
Harris, J. A., & Benedict, F. G. (2014) · Medical Entomology and Zoology · Cited by 1,847
A Controlled Clinical Trial of High-Dose Methylprednisolone in the Treatment of Severe Sepsis and Septic Shock
Bone, R. C., Fisher, C. J., Clemmer, T. P., Slotman, G. J., Metz, C. A., BALK, R. A., & The Methylprednisolone Severe Sepsis Study Group (1987) · New England Journal of Medicine · doi:10.1056/nejm198709103171101 · Cited by 1,437
Enteral Versus Parenteral Feeding Effects on Septic Morbidity After Blunt and Penetrating Abdominal Trauma
Kudsk, K. A., Croce, M. A., Fabian, T. C., Minard, G., Tolley, E. A., PORET, H. A., KUHL, M. R., & Brown, R. O. (1992) · Annals of Surgery · doi:10.1097/00000658-199205000-00013 · Cited by 1,149
Epidemiology of trauma deaths
Baker, C. C., Oppenheimer, L., Stephens, B. G., Lewis, F. R., & Trunkey, D. D. (1980) · The American Journal of Surgery · doi:10.1016/0002-9610(80)90431-6 · Cited by 850
TEN versus TPN following Major Abdominal Trauma—Reduced Septic Morbidity
Moore, F. A., Moore, E. E., Jones, T. N., McCroskey, B. L., & Peterson, V. M. (1989) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-198907000-00003 · Cited by 818
Clinical and Metabolic Efficacy of Glutamine-supplemented Parenteral Nutrition after Bone Marrow Transplantation
Ziegler, T. R., Young, L. S., Benfell, K., Scheltinga, M. R., Hortos, K., BYE, R. L., Morrow, F. D., Jacobs, D. O., Smith, R. J., Antin, J. H., et al. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-116-10-821 · Cited by 752
Glutamine and the preservation of gut integrity
van der Hulst, R. R. W. J., von Meyenfeldt, M. F., Deutz, N. E. P., Soeters, P. B., Brummer, R. J. M., von Kreel, B. K., & Arends, J. W. (1993) · The Lancet · doi:10.1016/0140-6736(93)90939-e · Cited by 657

Show all 32 references

Sorted by citations

Items 501–600 of 623

Glutathione in Sepsis and Multiple Organ Failure
Fläring, U., & Wernerman, J. (2009) · Springer eBooks · doi:10.1007/978-0-387-77383-4_42 · Cited by 1
When is Enteral Nutrition Support an Effective Strategy?
Posthauer, M. E. (2006) · Advances in Skin & Wound Care · doi:10.1097/00129334-200606000-00010 · Cited by 1
How to Feed Critically Ill Patients
Hong, S. (2015) · JOURNAL OF ACUTE CARE SURGERY · doi:10.17479/jacs.2015.5.1.1 · Cited by 1
“글루타민의 정맥투여는 중환자치료에 서 강력히 권고하고 있으나 경구투여는 주요 수술환자, 중증 외상 및 화상환자에서 글루타민의 투여효과는 입증되었다[24-30].”
Recomendaciones para el soporte nutricional y metabólico especializado del paciente crítico. Actualización. Consenso SEMICYUC-SENPE: Paciente neurocrítico
Escribano, J. A., Meseguer, I. H., & García-Quijada, R. C. (2011) · Medicina Intensiva · doi:10.1016/s0210-5691(11)70016-x · Cited by 1
Ernährung des Intensivpatienten
Rümelin, A. (2015) · Springer eBooks · doi:10.1007/978-3-662-46500-4_13 · Cited by 1
Parenteral glutamine in critical illness: just what the gut needs
Pullicino, E. (2012) · OAR@UM (University of Malta) · Cited by 1
Inflammation and Innate Immune Response
(2010) · CRC Press eBooks · doi:10.1201/ebk1439813621-c6 · Cited by 1
Nutritional support with glutamine according to recommendations of the European Society for Clinical Nutrition and Metabolism (ESPEN)
Kędziora, S., Słotwiński, R., & Dąbrowska, A. (2010) · Gastroenterology Review · doi:10.5114/pg.2010.17262 · Cited by 1
“[21] w badaniu z randomizacją wykonanym w grupie 72 chorych po rozległych urazach [skala ciężkości urazu (Injury Severity Score – ISS) > 20] stwierdzili, że w porównaniu z dojelitowym żywieniem standardowym, żywienie wzbogacone glutaminą (30,5 g/100 g białka przez okres minimum 5 dni) powoduje istotne obniżenie często…”
Effect of Glutamine on Intestinal Function in Critically Ill Patients
Tsvetkov, D. S. (2009) · General Reanimatology · doi:10.15360/1813-9779-2009-3-74 · Cited by 1
Pharmaconutrition in the Critically Ill Patient
Preiser, J., Malherbe, C., & Santacruz, C. A. (2017) · Springer eBooks · doi:10.1007/978-3-319-64010-5_19 · Cited by 1
Special Nutrition of the Surgical Neonate
Jaksic, T., & Kang, J.-K. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-2603-9.00016-8 · Cited by 1
Nutritional Support for Neurocritically Ill Patients
Jeong, H.-B., Park, S., & Ryu, H. G. (2018) · Journal of Neurocritical Care · doi:10.18700/jnc.180070 · Cited by 1
Critical Illness
Newton, L., & Heimburger, D. C. (2006) · Elsevier eBooks · doi:10.1016/b978-0-323-03952-9.50029-5 · Cited by 1
Glutamine Supplementation to Critically Ill Patients?
Wernerman, J. (2014) · Springer eBooks · doi:10.1007/978-3-319-03746-2_47 · Cited by 1
Inmunonutrición
Sanz, A., Celaya, S., Gracia, P., Gracia, M. L., & Albero, R. (2004) · Endocrinología y Nutrición · doi:10.1016/s1575-0922(04)74607-0 · Cited by 1
Nutritional Support in Intensive Care Unit (ICU) Patients
Preiser, J., Chioléro, R. L., & Singer, P. (2005) · Cited by 1
Trauma and Acute Care Surgery
Taylor, M. D., & Krishnan, K. (2015) · CRC Press eBooks · doi:10.1201/b18386-29 · Cited by 13
Yoğun Bakım Hastalarında Erken Enteral İmmünonütrisyon Uygulamasının Enflamatuvar Yanıta Etkisi
Çelik, F., & Edipoğlu, İ. S. (2019) · Türk yoğun bakım derneği dergisi/Türk yoğun bakım dergisi · doi:10.4274/tybd.galenos.2018.28290 · Cited by 1
Prevention of Critical Illness: Determinants of Risk
Bion, J. (1999) · Yearbook of intensive care and emergency medicine · doi:10.1007/978-3-662-13453-5_1 · Cited by 1
Nutrition des traumatisés graves
Tueux, O., Petit, L., Erny, P., & Sztark, F. (2007) · Springer eBooks · doi:10.1007/978-2-287-33475-7_61 · Cited by 1
Applications pratiques de la nutrition entérale précoce chez les malades de réanimation
Zazzo, J. (1999) · Nutrition Clinique et Métabolisme · doi:10.1016/s0985-0562(99)80011-9 · Cited by 1
L'intestin du patient agressé
Preiser, J., & Vincent, J. (2000) · Nutrition Clinique et Métabolisme · doi:10.1016/s0985-0562(00)80011-4 · Cited by 1
Nutrizione enterale nell’adulto
Boulétreau, P., Berger, M. M., Berrada, Boles, J. M., Chioléro, R. L., Gente-Dobez, A., Lerebours, É., & Renault (2008) · EMC - Anestesia-Rianimazione · doi:10.1016/s1283-0771(08)70295-0 · Cited by 1
Further evidence for the beneficial effects of glutamine in the nutrition of ICU patients
Wernerman, J. (2002) · Nutrition · doi:10.1016/s0899-9007(02)00865-1 · Cited by 1
Clinical Strategies for Prevention of Bacterial Translocation
Druml, W. (1999) · Springer eBooks · doi:10.1007/978-3-642-60200-9_13 · Cited by 1
Discussion
Furukawa, S. (1999) · Nutrition · doi:10.1016/s0899-9007(99)00076-3 · Cited by 1
Glutamine and Wound Healing
Agarwal, S., Schoemann, M. B., Bechtold, C. D., & Lentz, C. W. (2006) · CRC series in modern nutrition science · doi:10.1201/9780203500231.ch5 · Cited by 1
“Improved immune function from glutamine supplementation also results in fewer positive microbial cultures and a decreased number of clinical infections, including pneumonia, bacteremia, and sepsis [71,76,81].”
Background
Enteral Nutrition after Severe Burn
Woodside, K. J., & Wolf, S. E. (2005) · Elsevier eBooks · doi:10.1016/b978-0-7216-0379-7.50032-2 · Cited by 1
Immunonutrition
Hartl, W. H., Rittler, P., & Jauch, K. ‐. (2007) · Intensivmedizin und Notfallmedizin · doi:10.1007/s00390-007-0772-z · Cited by 1
Acute Pancreatitis
Dejong, C. H. C., Greve, J. W. M., & Soeters, P. B. (2005) · Elsevier eBooks · doi:10.1016/b978-0-7216-0379-7.50041-3 · Cited by 1
Critical Care Nutrition
Ochoa, J. B., Heyland, D. K., & McClave, S. A. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-1367-1.00094-x · Cited by 1
Horizons in the Anesthetic Care of Injured, Operated, and Stressed Patients
Gullo, A., Berlot, G., & Galimberti, G. (2000) · Springer eBooks · doi:10.1007/978-1-4612-1222-5_67 · Cited by 1
Exploiting the Bioenergetics of Disease-Causing Lymphocytes for Selective Immunomodulation.
Wahl, D. R. (2012) · Deep Blue (University of Michigan)
Glutamine Supplementation in Multiple Trauma Patients
Balushi, R. M. A., Paratz, J. D., Cohen, J., & Banks, M. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1932-1_14
Soporte nutricional del paciente quemado
Saffle, J. R. (2009) · Elsevier eBooks · doi:10.1016/b978-84-458-1938-8.50021-0
Perioperative arginine metabolism in cancer : interorgan studies in mice
Vissers, Y. L. J. (2008) · doi:10.26481/dis.20080411yv
Prospektiv-randomisierte Doppelblindstudie zur Wirkung einer glutaminhaltigen parenteralen Ernährung auf Monozyten, Granulozyten und Infektionen nach distaler Ösophagusresektion
Kietzmann, C. (2009) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-15859
Vitamin and Antioxidant Supplementation: Critical Evaluation of Clinical Outcomes
Bistrian, B. R. (2002) · KARGER eBooks · doi:10.1159/000067514
“demonstrated a significant reduction in infection, but this did not translate into a significant reduction in hospital stay [54].”
Background
Protective Nutrients and Gastrointestinal Allergies
Duggan, C. (2004) · KARGER eBooks · doi:10.1159/000077649
Immunonutrition in Intensive Care
Weimann, A., & Ludwig, D. (2014) · Springer eBooks · doi:10.1007/978-1-4614-8503-2_106-1
Metabolic and cellular effects of carbohydrate-based preconditioning drinks
Awad, S. (2010) · Nottingham ePrints (University of Nottingham)
Preventing ventilator-associated pneumonia: what is the evidence? A systematic review and meta-analysis
Vögele, S. (2010) · doi:10.5282/edoc.12283
The Interaction Between Nutrition and Inflammatory Stress Throughout the Life Cycle
Grimble, R. F. (2006) · Humana Press eBooks · doi:10.1385/1-59259-952-4:387
Glutamine Supplementation in ICU Patients
Berg, A., Rooyackers, O., & Wernerman, J. (2009) · Springer eBooks · doi:10.1007/978-3-540-92276-6_65
“The effect on immunecompetent cells may be the background to the beneficial effect on infectious morbidity reported in a number of patient groups such as intensive care patients [2, 17, 25], hematological patients [26, 27], postoperative patients [28], oncological patients [29], premature children [30], and gastroente…”
Background
Potential for Glutamine Supplementation in Critically Ill Children
Briassouli, E., Marino, L. V., & Briassoulis, G. C. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1932-1_16
GLUTAMINE TO ICU PATIENTS
Berg, A. (2007) · Figshare
Thérapie nutritionnelle chez le patient polytraumatisé :une nouvelle approche
Guinvarch, A. (2007) · Nutrition Clinique et Métabolisme · doi:10.1016/s0985-0562(07)80003-3
Nutrition and Oxidants in the Critically Ill Patient
Richards, G. A. (2004) · Clinical Pulmonary Medicine · doi:10.1097/01.cpm.0000127202.22102.48
Glutamine: Role in the Fetus and Low-birthweight Infant
Neu, J. (2000) · NeoReviews · doi:10.1542/neo.1-11-e215
Cholestase bij pasgeborenen als gevolg van parenterale voeding
Veere, C. N. V. D., Bijleveld, C. M. A., Sauer, P. J. J., Kuipers, F., & Verkade, H. J. (2001) · Tijdschrift voor kindergeneeskunde · doi:10.1007/bf03061355
Mind the gap : experimental studies on splanchnic hypoperfusion and gastrointestinal integrity loss in man
van Wijck, K. (2013) · Research Publications (Maastricht University) · doi:10.26481/dis.20130704kw
Nutrition des traumatisés crâniens graves
Petit, L., & Sztark, F. (2011) · Nutrition Clinique et Métabolisme · doi:10.1016/j.nupar.2011.09.005
Immune-enhancing Diets
Zaloga, G. P., & Marik, P. E. (2000) · Critical Care Medicine · doi:10.1097/00003246-200003000-00061
Quoi de neuf en nutrition aux soins intensifs ?
Garrel, D. R. (2001) · Réanimation · doi:10.1016/s1164-6756(01)00157-8
Does Immunonutrition Make an Impact? It Depends on the Analysis
Bihari, D. J. (2000) · Critical Care Medicine · doi:10.1097/00003246-200003000-00063
Les pharmaconutriments azotésdu laboratoire au lit du malade
Cynober, L. (2002) · La Revue de Médecine Interne · doi:10.1016/s0248-8663(02)80050-9
Pharmaconutriments et immunonutrition
Preiser, J., & Malherbe, C. (2011) · Springer eBooks · doi:10.1007/978-2-287-99027-4_21
GLUTAMINE: A NOVEL AND POTENT THERAPEUTIC FOR ACUTE SPINAL CORD INJURY
Macdonald, R. H., & O’Dwyer, S. (2008)
Infection in the critically ill surgical patient
Treggiari-Venzi, M. M., Romand, J.-A., Garbino, J., & Suter, P. M. (1999) · Best practice & research. Clinical anaesthesiology · doi:10.1053/bean.1999.0034
SKELETAL MUSCLE METABOLISM IN CRITICALLY ILL PATIENTS
Gamrin, L. (2000)
The metabolic pathway of (alanyl-)glutamine into citrulline and arginine in surgical patients
Ligthart‐Melis, G. C. (2008) · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam)
Nutritional Support for Wound Healing Douglas MacKay, ND,
Miller, A. L. (2003)
The effect of enteral immune-enhancing diet (immunonutrition) on the apoptotic signaling pathways of peripheral blood lymphocytes in patients after pancreatic cancer surgery
Lech, G., Zaleska, M., Kędziora, S., Gulak, G., & Krasnodębski, W. I. (2010)
The up-regulation of pro-apoptotic signalling systems in peripheral blood lymphocytes of malnourished patients with pancreatic cancer after preoperative enteral immune-enhancing diet (immunonutrition) Aktywacja proapoptotycznych szlaków sygnałowych w limfocytach krwi obwodowej niedożywionych chorych na raka trzustki po przedoperacyjnym dojelitowym żywieniu wspomagającym odporność (immunonutrition)
Olszewski, W. L., Lech, G., Zaleska, M., Słotwińska, S. M., & Krasnodebski, I. W. (2011)
Protein and amino acid metabolism: comparison of stressed and nonstressed states.
Fürst, P., & Cresci, G. (2005)
against endotoxin shock in the rat Glutamine induces heat shock protein and protects
Chang, E. B., Wischmeyer, P. E., Kahana, M. D., Ren, H., Xue, H., Slavov, D. B., Pierre, J. F., Heneghan, A. F., Lawson, C. M., Rosemary, A., et al. (2015)
Reply to PG Boelens et al
Buchman, A. L. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.1.254
Glutamine Supplementation in Multiple Trauma and Critical Illness
Balushi, R. M. A., Paratz, J. D., Cohen, J., & Banks, M. (2014) · Springer eBooks · doi:10.1007/978-1-4614-8503-2_141-1
Frühpostoperative enterale Ernährung
Kemen, M. (2003) · Springer eBooks · doi:10.1007/978-3-642-55896-2_24
Verträglichkeit und Sicherheit enteraler Pharmakonutrition in der frühen postoperativen Phase bei Patienten mit gastrointestinalen Tumoren
Bochum, R.-U. (2003)
Nutrition Support in Trauma Patients
Lee, S. H., Jang, J. Y., & Lee, J. G. (2013) · Journal of Clinical Nutrition · doi:10.15747/jcn.2013.5.3.90
Prise en charge d’une dénutrition aiguë chez un sujet agressé
Fulgencio, J.-P. (2003) · Nutrition Clinique et Métabolisme · doi:10.1016/s0985-0562(03)00031-1
Do Critically Ill Patients Need Enteral Glutamine Supplementation?
Edmunds, C., Ziegler, J., & MacDonald, A. (2012) · Topics in Clinical Nutrition · doi:10.1097/tin.0b013e31826f9032
Alterations in innate antibacterial response after immunomodulatory nutrition
Słotwiński, R., Słotwińska, S. M., Kędziora, S., & Dąbrowska, A. (2012) · Gastroenterology Review · doi:10.5114/pg.2012.29876
“Glutamine is an important energy source for lymphatic tissue and glutamine-enriched enteral nutrition has been found to reduce the incidence of sepsis in trauma patients, due to maintaining the integrity of intestinal mucosa [5, 48, 49].”
Background
Nutritional Support in Gastrointestinal Disease
Visschers, R. G. J., van Gemert, W. G., & Soeters, P. B. (2008)
Uso de terapia nutricional imunomoduladora em pacientes politraumatizados: uma revisão da
da Costa, C. L. (2010)
Meer aandacht voor eiwit in de voeding van volwassen chronisch zieke patiënten met neiging tot gewichtsverlies
Tholen, A. J., Eo, N., Berghmans, R., Legemaate, J., Wa, N., & Huisman, J. (1999)
Nutraceuticals and Inflammation in Athletes
Plunkett, B., Callister, R., & Garg, M. L. (2006) · Modern nutrition · doi:10.1201/9781420006186.ch21
12. Enteral nutrition with L-glutamine in sepsis patients
Cavalcante, A. A. M., de Vasconcelos, P. R. L., & Cavalcante, J. F. M. (2016) · Wageningen Academic Publishers eBooks · doi:10.3920/978-90-8686-822-3_12
Immunonutrients and Evidence for Their Use in Hospitalized Adults Receiving Artificial Nutrition
Calder, P. C. (2014) · CRC Press eBooks · doi:10.1201/b17311-14
Protein and amino acid metabolism: stress versus nonstress states
Cresci, G. (2015) · CRC Press eBooks · doi:10.1201/b18386-5
Nutritional and Metabolic Therapy
Martindale, R. G., Enomoto, T. M., & McCarthy, M. S. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-1679-5.00028-4
Heat Shock Protein 70 and the relationship to glutamine in the critically ill child
Marino, L. V. (2012) · doi:10.25560/10748
Supplementation Of Enteral Feeds Of Critically Ill Patients In The Medical Intensive Care Unit With Glutamine
Geng, E. H. (2004)
Immunonutrition and lipopolysaccharide - induced Toll-like receptor signaling
Ba, B. J., & Kędziora, S. (2009)
intestinal injury during exercise: strategies for evaluation and
van Wijck, K., Lenaerts, K., Grootjans, J., Wijnands, K. A. P., Poeze, M., van Loon, L. J. C., Dejong, C. H. C., & Buurman, W. A. (2012)
Pneumatic stabilization of iatrogenic flail chest with CPAP: a case report.
Dutta, B., & Kashyap, L. (2010) · PubMed
The effect of therapeutic exercise and metabolic acidosis on skeletal muscle metabolism in chronic kidney disease
Clapp, E. L. (2010) · OpenGrey (Institut de l'Information Scientifique et Technique)
Approach to Acquired Malnutrition in the Hospitalized Patient with Respiratory and Critical Illness
Kret-Sudjian, E., Kenyon, N. J., & Molla, M. (2017) · Hospital Medicine Clinics · doi:10.1016/j.ehmc.2017.05.010
Nutrition Support in Critically Ill Patients
Latifi, R., & Con, J. (2018) · Wiley eBooks · doi:10.1002/9781119317913.ch19
Nutrition Support of the Septic Patient
Rodríguez, C. J. G. (2002) · Springer eBooks · doi:10.1007/978-3-642-57119-0_28
Методичні рекомендації ESPEN щодо клінічного харчування у відділенні інтенсивної терапії
Singer, P., Blaser, A. R., Berger, M. M., Alhazzani, W. A., Calder, P. C., Casaer, M. P., Hiesmayr, M., Mayer, K., Montejo, J. C., Pichard, C., et al. (2019) · Pain anesthesia and intensive care · doi:10.25284/2519-2078.2(87).2019.171009
Current Guidelines on Clinical Nutrition in Intensive Care Units Based on ESPEN 2018
Lee, A., Kim, E., Park, C.-M., & Rha, M. Y. (2019) · Journal of Clinical Nutrition · doi:10.15747/jcn.2019.11.2.31
Re: Missing Effect of Glutamine Supplementation on the Surgical Outcome after Pancreaticoduodenectomy for Periampullary Tumors: a Prospective, Randomized, Double‐blind, Controlled Clinical Trial
Dejong, C. H. C. (2006) · World Journal of Surgery · doi:10.1007/s00268-006-0393-x
Biology of Perioperative Nutrition: An Update
Latifi, R. (2021) · Hot topics in acute care surgery and trauma · doi:10.1007/978-3-030-62215-2_7
Ernährung des kritisch kranken Patienten
Wrigge, H., & Putensen, C. (2005) · Springer eBooks · doi:10.1007/3-540-26858-8_8
Ernährung des Intensivpatienten
Rümelin, A. (2008) · Springer eBooks · doi:10.1007/978-3-540-68317-9_15
Immunonutrition in der Intensivmedizin
Weimann, A. (2013) · Springer eBooks · doi:10.1007/978-3-642-40738-3_9
Burns
McCarthy, H., & Gurry, C. (2007) · doi:10.1002/9780470692004.ch25
Burns
McCarthy, H. O., & Hunt, D. (2001) · doi:10.1002/9780470690369.ch25

Authors: Houdijk, A. P., Rijnsburger, E. R., Jansen, J., Wesdorp, R. I., Weiss, J. K., McCamish, M. A., Teerlink, T., Meuwissen, S. G., Haarman, H. J. T. M., Thijs, L. G., & van Leeuwen, P. A.
Affiliations: Amsterdam UMC Location University of Amsterdam (NL)
The Ohio State University (US)
Corresponding author: van Leeuwen, Paul AM
ORCID: Houdijk, Alexander PJ
Jansen, Jaap
Venue: The Lancet
Publisher: Elsevier BV
Published: 1998-09
Volume: 352
Issue: 9130
Pages: 772-776
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/s0140-6736(98)02007-8
OpenAlex: W2137842935
Cited by: 620
References: 32
Citations by year: 2026: 2 · 2025: 2 · 2024: 5 · 2023: 7 · 2022: 3 · 2021: 7 · 2020: 7 · 2019: 9 · 2018: 7 · 2017: 10 · 2016: 16 · 2015: 19 · 2014: 24 · 2013: 22 · 2012: 18
FWCI: 38.52
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
Funders: Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
Keywords: glutamine supplementation, enteral nutrition, polytrauma, infection control, pneumonia, bacteremia, sepsis, critically ill patients, nutritional support
MeSH terms: Adult, Aged, Arginine, Cross Infection, Enteral Nutrition, Glutamine, Humans, Length of Stay, Middle Aged, Multiple Trauma, Pneumonia, Injury Severity Score, Bacteremia

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks