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Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial

Overgaard, Marie, Jensen, Maj-Britt, Overgaard, Jens, Hansen, Per S, Rose, Carsten, Andersson, Michael, Kamby, Claus, Kjaer, Mogens, Gadeberg, Carl C, Rasmussen, Birgitte Bruun, Blichert-Toft, Mogens, Mouridsen, Henning T·1999·The Lancet

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Research works printed but not linked: 28

  1. Dombernowsky, 1988, Adjuvant therapy of premenopausal and menopausal high-risk breast cancer patients: present status of the Danish Breast Cancer Cooperative Group Trials 77-B and 82-B, Acta Oncol, 27, 691, 10.3109/02841868809091771 · doi:10.3109/02841868809091771
  2. Mouridsen, 1988, Adjuvant treatment of postmenopausal patients with high risk primary breast cancer: results from the Danish adjuvant trials DBCG 77 C and DBCG 82 C, Acta Oncol, 27, 699, 10.3109/02841868809091772 · doi:10.3109/02841868809091772
  3. 1992, Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy (part 2), Lancet, 339, 71, 10.1016/0140-6736(92)90997-H · DOI · Paper page
  4. Bonadonna, 1995, Adjuvant cyclophosphamide, methotrexate, and fluorouracil in nodepositive breast cancer: the results of 20 years of follow-up, N Engl J Med, 332, 901, 10.1056/NEJM199504063321401 · DOI · Paper page
  5. Overgaard, 1988, Postmastectomy irradiation in high-risk breast cancer patients: present status of the Danish Breast Cancer Cooperative Group trials, Acta Oncol, 27, 707, 10.3109/02841868809091773 · doi:10.3109/02841868809091773
  6. Cuzick, 1987, Overview of randomized trials comparing radical mastectomy without radiotherapy against simple mastectomy with radiotherapy in breast cancer, Cancer Treat Rep, 71, 7
  7. 1995, Effects of radiotherapy and surgery in early breast cancer: an overview of the randomized trials, N Engl J Med, 333, 1444, 10.1056/NEJM199511303332202 · DOI · Paper page
  8. Harris, 1996, Breast-conserving therapy as a model for creating new knowledge in clinical oncology, Int J Radiat Oncol Biol Phys, 35, 641, 10.1016/0360-3016(96)00215-5 · doi:10.1016/0360-3016(96)00215-5
  9. Cuzick, 1987, Overview of randomized trials of postoperative adjuvant radiotherapy in breast cancer, Cancer Treat Rep, 71, 15
  10. Cuzick, 1994, Cause-specific mortality in long-term survivors of breast cancer who participated in trials of radiotherapy, J Clin Oncol, 12, 447, 10.1200/JCO.1994.12.3.447 · DOI · Paper page
  11. Overgaard, 1997, Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy, N Engl J Med, 337, 949, 10.1056/NEJM199710023371401 · DOI · Paper page
  12. Ragaz, 1997, Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer, N Engl J Med, 337, 956, 10.1056/NEJM199710023371402 · DOI · Paper page
  13. Yarnold, 1997, Benefits of postmastectomy radiotherapy, Lancet, 350, 1415, 10.1016/S0140-6736(05)64204-3 · doi:10.1016/s0140-6736(05)64204-3
  14. Recht, 1998, Postmastectomy radiotherapy: questions for the twenty-first century, J Clin Oncol, 16, 2886, 10.1200/JCO.1998.16.8.2886 · doi:10.1200/jco.1998.16.8.2886
  15. West Andersen, 1988, Danish Breast Cancer Cooperative Group (DBCG): a description of the register of the nation-wide programme for primary breast cancer, Acta Oncol, 27, 627, 10.3109/02841868809091763 · doi:10.3109/02841868809091763
  16. Johansen, 1990, Simple mastectomy with postoperative irradiation versus extended radical mastectomy in breast cancer: a twenty-five year follow-up of a randomized trial, Acta Oncol, 29, 709, 10.3109/02841869009092988 · DOI
  17. Syrak Hansen, 1997, Quality control of end results in a Danish adjuvant breast cancer multi-center trial, Acta Oncol, 36, 711, 10.3109/02841869709001342 · DOI
  18. Gelman, 1990, Improved methodology for analyzing local and distant recurrence, J Clin Oncol, 8, 548, 10.1200/JCO.1990.8.3.548 · DOI · Paper page
  19. Overgaard, 1998, Radiotherapy and chemotherapy in high-risk breast cancer, N Engl J Med, 338, 331
  20. 1996, Randomized trial of two versus five years of adjuvant tamoxifen for postmenopausal early stage breast cancer, J Natl Cancer Inst, 88, 1543, 10.1093/jnci/88.21.1543 · DOI · Paper page
  21. 1998, Tamoxifen for early breast cancer: an overview of the randomised trials, Lancet, 351, 1451, 10.1016/S0140-6736(97)11423-4 · DOI · Paper page
  22. Willsher, 1997, Investigation of primary tamoxifen therapy for elderly patients with operable breast cancer, Breast, 6, 150, 10.1016/S0960-9776(97)90557-9 · doi:10.1016/s0960-9776(97)90557-9
  23. Rose, 1994, A randomized DBCG trial of adjuvant tamoxifen (TAM) + radiotherapy vs TAM alone vs TAM + CMF in postmenopausal breast cancer patients with high risk of recurrence, Eur J Cancer, 30A, S28
  24. Bentzen, 1996, Radiotherapy-related lung fibrosis enhanced by tamoxifen, J Natl Cancer Inst, 88, 918, 10.1093/jnci/88.13.918 · DOI · Paper page
  25. Højris, 1998, Morbidity and mortality of ischaemic heart disease in 3083 high-risk breast cancer patients given adjuvant systemic treatment with or without postmastectomy irradiation, Radiother Oncol, 48, 475
  26. Arriagada, 1995, Adequate locoregional treatment for early breast cancer may prevent secondary dissemination, J Clin Oncol, 14, 2869, 10.1200/JCO.1995.13.12.2869 · DOI · Paper page
  27. Rutqvist, 1993, Adjuvant radiation therapy versus surgery alone in operable cancer: long-term follow-up of a randomized clinical trial, Radiother Oncol, 26, 104, 10.1016/0167-8140(93)90090-U · doi:10.1016/0167-8140(93)90090-u
  28. Recht, 1995, The return (?) of postmastectomy radiotherapy, J Clin Oncol, 13, 2861, 10.1200/JCO.1995.13.12.2861 · doi:10.1200/jco.1995.13.12.2861

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Metadata

Authors
Overgaard, M., Jensen, M.-B., Overgaard, J., Hansen, P. S., Rose, C., Andersson, M., Kamby, C., Kjaer, M., Gadeberg, C. C., Rasmussen, B. B., Blichert-Toft, M., & Mouridsen, H. T.
Venue
The Lancet
Publisher
Elsevier BV
Published
1999-05
Volume
353
Issue
9165
Pages
1641-1648
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W2168517539
Cited by
1,602
References
0
FWCI
19.80
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. https://app.cochat.ai/papers/10.1016/s0140-6736(98)09201-0
The paper
Overgaard, M., Jensen, M.-B., Overgaard, J., Hansen, P. S., Rose, C., Andersson, M., Kamby, C., Kjaer, M., Gadeberg, C. C., Rasmussen, B. B., Blichert-Toft, M., & Mouridsen, H. T. (1999). Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. The Lancet. https://doi.org/10.1016/s0140-6736(98)09201-0

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.