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Exogenous Fungal Endophthalmitis
Open accessAbstract
The authors report 19 cases of exogenous fungal endophthalmitis managed between 1969 and 1986. These developed after ocular surgery (5 cases), after trauma (6 cases), by intraocular spread from fungal keratitis (4 cases), after therapeutic keratoplasty for keratitis (3 cases), and by spontaneous infection of a filtration bleb (1 case). The diagnosis of endophthalmitis was made from 3 days to 4 months after surgery or trauma. In patients with preexisting keratitis, endophthalmitis was noted 2 weeks to 5 months after the onset of keratitis. Seventeen cases were caused by filamentous fungi; two were caused by yeast. Fusarium (6 cases) and Acremonium (3 cases) accounted for approximately one half of the isolates. Forty-two percent of the patients recovered 20/400 or better acuity (3 of 5 postoperative cases, 4 of 6 trauma cases, and 1 of 4 keratitis cases). The clinical and microbiologic features of these cases are presented, and recommendations for management are offered.
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Citations
Cited by
Fusarium Infections in Immunocompromised Patients
Nucci, M., & Anaissie, E. (2007) · Clinical Microbiology Reviews · doi:10.1128/cmr.00014-07 · Cited by 983
Boutati, E. I., & Anaissie, E. J. (1997) · Blood · doi:10.1182/blood.v90.3.999 · Cited by 587
Fungal and Parasitic Infections of the Eye
Klotz, S. A., Penn, C. C., Negvesky, G. J., & Butrus, S. I. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.4.662 · Cited by 309
Treatment outcomes in a 10-year study of endogenous fungal endophthalmitis
Essman, T. F., Flynn, H. W., Smiddy, W. E., Brod, R. D., Murray, T. G., Davis, J. L., & Rubsamen, P. E. (1997) · Ophthalmic Surgery, Lasers and Imaging Retina · doi:10.3928/1542-8877-19970301-03 · Cited by 264
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Metadata
- Authors
- Pflugfelder, S. C., Flynn, H. W., Zwickey, T. A., Forster, R. K., Tsiligianni, A., Culbertson, W. W., & Mandelbaum, S.
- Venue
- Ophthalmology
- Publisher
- Elsevier BV
- Published
- 1988-01
- Volume
- 95
- Issue
- 1
- Pages
- 19-30
- ISSN
- 0161-6420 (ISSN-L)
- OpenAlex
- W1983978508
- Cited by
- 216
- References
- 0
- FWCI
- 3.59
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Pflugfelder, S. C., Flynn, H. W., Zwickey, T. A., Forster, R. K., Tsiligianni, A., Culbertson, W. W., & Mandelbaum, S. (1988). Exogenous Fungal Endophthalmitis. Ophthalmology. https://doi.org/10.1016/s0161-6420(88)33229-x
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