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The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.

Fusarium Infections in Immunocompromised Patients

Open access
Nucci, Marcio, Anaissie, Elias·2007·Clinical Microbiology Reviews

Abstract

SUMMARY: Fusarium species cause a broad spectrum of infections in humans, including superficial, locally invasive, and disseminated infections. The clinical form of fusariosis depends largely on the immune status of the host and the portal of entry, with superficial and localized disease occurring mostly in immunocompetent patients and invasive and disseminated disease affecting immunocompromised patients. Risk factors for severe fusariosis include prolonged neutropenia and T-cell immunodeficiency, especially in hematopoietic stem cell transplant recipients with severe graft-versus-host disease. The most frequent presentation of disseminated fusariosis is a combination of characteristic cutaneous lesions and positive blood cultures, with or without lung or sinus involvement. The prognosis is poor and is determined largely by degree of immunosuppression and extent of infection, with virtually a 100% death rate among persistently neutropenic patients with disseminated disease. These infections may be clinically suspected on the basis of a constellation of clinical and laboratory findings, which should lead to prompt therapy. Treatment options include the lipid formulations of amphotericin B, voriconazole, and posaconazole. Prevention of fusarial infection among high-risk patients should be considered.

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Metadata

Authors
Nucci, M., & Anaissie, E.
Venue
Clinical Microbiology Reviews
Published
2007-10
Volume
20
Issue
4
Pages
695-704
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W2121711759
Cited by
983
References
63
FWCI
18.22
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Fusarium Infections in Immunocompromised Patients. https://app.cochat.ai/papers/10.1128/cmr.00014-07
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Nucci, M., & Anaissie, E. (2007). Fusarium Infections in Immunocompromised Patients. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.00014-07

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