CoChat
Sign Up
Cited by 306Acupuncture Treatment Research StudiesHeart Rate Variability and Autonomic ControlVagus Nerve Stimulation Research

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Effect of sensory stimulation (acupuncture) on sympathetic and parasympathetic activities in healthy subjects

Haker, Eva, Egekvist, Henrik, Bjerring, Peter·2000·Journal of the Autonomic Nervous System
DOI 10.1016/s0165-1838(99)00090-9
Open this paper in CoChat — free account

Abstract

It has been postulated that sensory stimulation (acupuncture) affects the cardiovascular system via the autonomic nervous system. Previously, skin temperature, thermography, plethysmography and blood pressure changes have been used in evaluation of sympathetic nerve activity following acupuncture. By using power spectral analysis, the low frequency and high frequency components of heart rate variability can be calculated reflecting the sympathetic and parasympathetic activity. The purpose of this study was to investigate to what extent acupuncture applied into the thenar muscle and into the cavum concha of the ear induced changes in the sympathetic and/or parasympathetic nervous system in healthy subjects.Materials and methods Twelve healthy volunteers, six men and six women, mean age 34.4 (range 23-48) participated in three balanced, randomly distributed sessions. At an individual initial visit the 12 volunteers were introduced to the needle sensation by having a needle inserted into the point LI 11. The needle sensation was evoked and the subject was trained to identify the characteristic needle sensation. The introduction was followed by three test sessions.Session a A short acupuncture needle, (Seirin no 3, ∅0.20x15 mm) was inserted perpendicular into the earpoint, Lu 1, in the left inferior hemi-conchae.Session b An acupuncture needle (Hwato, ∅0.30x30 mm) was inserted perpendicular into the Hegu point (LI 4) in the middle of the right dorsal thenar muscle.Session c An acupuncture needle (Hwato, ∅0.30x30 mm) was inserted perpendicular superficially into the skin overlying the Hegu point on the left hand. Results. Stimulation of the ear induced a significant increase in the parasympathetic activity during the stimulation period of 25 min (P<0.05) and during the post-stimulation period of 60 min (P<0.05). No significant changes were observed in either the sympathetic activity, blood pressure or heart rate. Stimulation of the thenar muscle resulted in a significant increase in the sympathetic and the parasympathetic activity during the stimulation period (P<0.01) and during the post-stimulation period (P<0.01 and P<0.001, respectively). A significant decrease in the heart rate frequency (P<0.05) at the end of the post-stimulation period was also demonstrated. The superficial needle insertion into the skin overlaying the right thenar muscle caused a pronounced balanced increase in both the sympathetic and parasympathetic activity during the post stimulation period of 60 min (P<0.01) while no changes were observed during the stimulation period.Conclusion It is indicated that sensory stimulation (acupunctura) in healthy persons is associated with changed activity in the sympathetic and parasympathetic nervous system depending on site of stimulation and period of observation.

Overview

Integrity signals

Registry

Crossref · 10.1016/s0165-1838(99)00090-9

Cites

30 of 30 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 30 references

Research works printed but not linked: 3

  1. Berry, M.M., Standring, S.M., Bannister, L.H., 1995. Nervous system. In: Williams, P.L., Bannister, L.H., Berry, M.M., Collins, P., Dyson, M., Dussek, J.E., Ferguson, M.W.J. (Eds.), Grays anatomy. Churchill Livingstone/London, pp. 1251–1252.
  2. Essentials of Chinese Acupuncture, 1993. Foreign Language Press, Beijing.
  3. Suter, 1994, Does acupuncture influence the cardiovascular system via the central nervous system?, Schweiz Med. Wochenschr., 124, 36

Cited by

Sorted by citations

Related

See all

Metadata

Authors
Haker, E., Egekvist, H., & Bjerring, P.
Affiliations
  • Karolinska Institutet (SE)
  • Aarhus University Hospital (DK)
Corresponding author
Haker, Eva
ORCID
Bjerring, Peter
Venue
Journal of the Autonomic Nervous System
Publisher
Elsevier BV
Published
2000-02
Volume
79
Issue
1
Pages
52-59
ISSN
0165-1838 (ISSN-L)
DOI
10.1016/s0165-1838(99)00090-9
OpenAlex
W2049455604
Cited by
306
References
30
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 12 · 2022: 6 · 2021: 8 · 2020: 11 · 2019: 16 · 2018: 10 · 2017: 10 · 2016: 4 · 2015: 16 · 2014: 21 · 2013: 22 · 2012: 23
FWCI
11.75
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of the Autonomic Nervous System (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Acupuncture Treatment Research Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
Keywords
acupuncture, sensory stimulation, sympathetic nervous system, parasympathetic nervous system, heart rate variability, autonomic nervous system, thenar muscles, auricular acupuncture, blood pressure, heart rate, acupuncture training, needle sensation, healthy volunteers, power spectrum analysis
MeSH terms
Adult, Blood Pressure, Diastole, Female, Hand, Heart Rate, Humans, Male, Middle Aged, Parasympathetic Nervous System, Reference Values, Sympathetic Nervous System, Acupuncture Therapy, Muscle, Skeletal, Acupuncture, Ear

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review