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Presynaptic nicotinic ACh receptors
Abstract
Nicotinic ACh (nACh) receptors in the CNS are composed of a diverse array of subunits and have a range of pharmacological properties. However, despite the fact that they are ligand-gated cation channels, their physiological functions have not been determined. This has led to increased interest in presynaptic nACh receptors that act to modulate the release of transmitter from presynaptic terminals.
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“Instead, central cholinergic neurotransmission predominantly changes neuronal excitability, alters presynaptic release of neurotransmitters, and coordinates the firing of groups of neurons (Kawai et al., 2007; Rice and Cragg, 2004; Wonnacott, 1997; Zhang and Sulzer, 2004).”
From Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior (2012) · cites this paper as Wonnacott, 1997
In the citing paper
“In addition, stimulation of nAChRs can increase the release of glutamate, GABA, dopamine (DA), ACh, norepinephrine, and serotonin (McGehee et al., 1995; Wonnacott, 1997) (Figure 1).”
From Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior (2012) · cites this paper as Wonnacott, 1997
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Séguéla, P., Wadiche, J. I., Dineley‐Miller, K., Dani, J., & Jw, P. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-02-00596.1993 · Cited by 1,471
Lev, S., Moreno, H., Martinez, R., Canoll, P., Peles, E., Musacchio, J. M., Plowman, G. D., Rudy, B., & Schlessinger, J. (1995) · Nature · doi:10.1038/376737a0 · Cited by 1,382
Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors
McGehee, D. S., Heath, M. J. S., Gelber, S., Devay, P., & Role, L. W. (1995) · Science · doi:10.1126/science.7569895 · Cited by 1,070
The Diversity of Neuronal Nicotinic Acetylcholine Receptors
Sargent, P. B. (1993) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.16.030193.002155 · Cited by 1,052
Wada, E., Wada, K., Boulter, J., Deneris, E. S., Heinemann, S., Patrick, J., & Swanson, L. W. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902840212 · Cited by 1,044
Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons
McGehee, D. S., & Role, L. W. (1995) · Annual Review of Physiology · doi:10.1146/annurev.ph.57.030195.002513 · Cited by 1,022
Hippocampal synaptic transmission enhanced by low concentrations of nicotine
Gray, R. G. F., Rajan, A. S., Radcliffe, K. A., Yakehiro, M., & Dani, J. A. (1996) · Nature · doi:10.1038/383713a0 · Cited by 947
Flores, C. M., Rogers, S. W., Pabreza, L. A., Wolfe, B. B., & Kellar, K. J. (1992) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)08832-7 · Cited by 880
Nicotinic Receptors in the Development and Modulation of CNS Synapses
Role, L. W., & Berg, D. K. (1996) · Neuron · doi:10.1016/s0896-6273(00)80134-8 · Cited by 762
Intercellular communication in the brain: Wiring versus volume transmission
Agnati, L. F., Zoli, M., Strömberg, I., & Fuxé, K. (1995) · Neuroscience · doi:10.1016/0306-4522(95)00308-6 · Cited by 569
Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment
Marks, M., Pauly, Jr., Gross, S., Deneris, E., Hermans-Borgmeyer, I., Heinemann, S., & Collins, A. (1992) · The Journal of Neuroscience · doi:10.1523/jneurosci.12-07-02765.1992 · Cited by 551
Clarke, P. B. S., & Pert, A. (1985) · Brain Research · doi:10.1016/0006-8993(85)90456-1 · Cited by 527
Nisell, M., Nomikos, G. G., & Svensson, T. H. (1994) · Synapse · doi:10.1002/syn.890160105 · Cited by 521
Functional contributions of α5 subunit to neuronal acetylcholine receptor channels
Ramírez-Latorre, J. A., Yu, C., Qu, X., Perin, F., Karlin, A., & Role, L. W. (1996) · Nature · doi:10.1038/380347a0 · Cited by 395
Peng, X., Gerzanich, V, Anand, R., Whiting, P. J., & Lindstrom, J. (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09730-5 · Cited by 391
Goldman, D. J., Deneris, E. S., Luyten, W. H. M. L., Kochhar, A., Patrick, J., & Heinemann, S. (1987) · Cell · doi:10.1016/0092-8674(87)90705-7 · Cited by 388
Mulle, C., Choquet, D., Korn, H., & Changeux, J. (1992) · Neuron · doi:10.1016/0896-6273(92)90115-t · Cited by 351
Grady, S., Marks, M. J., Wonnacott, S., & Collins, A. C. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb08322.x · Cited by 350
Self-citationAraujo, D. M., Lapchak, P. A., Robitaille, Y., Gauthier, S. G., & Quirion, R. (1988) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1988.tb02497.x · Cited by 332
Vernallis, A. B., Conroy, W. G., & Berg, D. K. (1993) · Neuron · doi:10.1016/0896-6273(93)90333-m · Cited by 304
Clarke, P. B. S., & Reuben, M. (1996) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1996.tb15232.x · Cited by 262
Partial agonist properties of cytisine on neuronal nicotinic receptors containing the beta 2 subunit
Papke, R. L., & Heinemann, S. F. (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09896-7 · Cited by 259
Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus
Léna, C., Changeux, J., & Mulle, C. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-06-02680.1993 · Cited by 255
Wada, E., McKinnon, D. H., Heinemann, S., Patrick, J., & Swanson, L. W. (1990) · Brain Research · doi:10.1016/0006-8993(90)90248-a · Cited by 254
del Toro, E. D., Juiz, J. M., Peng, X.-D., Lindstrom, J. M., & Criado, M. (1994) · The Journal of Comparative Neurology · doi:10.1002/cne.903490302 · Cited by 248
Vidal, C., & Changeux, J. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90558-w · Cited by 240
Schwartz, R. D., Lehmann, J. C., & Kellar, K. J. (1984) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1984.tb02818.x · Cited by 234
β3: A New Member of Nicotinic Acetylcholine Receptor Gene Family Is Expressed in Brain
Deneris, E. S., Boulter, J., Swanson, L. W., Patrick, J., & Heinemann, S. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83343-9 · Cited by 225
Conroy, W. G., Vernallis, A. B., & Berg, D. K. (1992) · Neuron · doi:10.1016/0896-6273(92)90031-8 · Cited by 208
Effects of Nicotine on Biological Systems II
Clarke, P. B. S., Quik, M., Adlkofer, F. X., & Thurau, K. (1995) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-7445-8 · Cited by 202
Mulle, C., Vidal, C., Benoit, P., & Changeux, J. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-08-02588.1991 · Cited by 200
Dineley‐Miller, K., & Patrick, J. (1992) · Molecular Brain Research · doi:10.1016/0169-328x(92)90244-6 · Cited by 194
Couturier, S., Erkman, L., Valera, S., Rungger, D., Bertrand, S., Boulter, J., Ballivet, M., & Bertrand, D. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)38201-2 · Cited by 190
Nicotinic Stimulation of [3H]Acetylcholine Release from Mouse Cerebral Cortical Synaptosomes
Rowell, P. P., & Winkler, D. L. (1984) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1984.tb06083.x · Cited by 182
(+)‐Anatoxin‐a Is a Potent Agonist at Neuronal Nicotinic Acetylcholine Receptors
Thomas, P., Stephens, M., Wilkie, G., Amar, M., Lunt, G. G., Whiting, P. J., Gallagher, T. C., Pereira, E. F. R., Alkondon, M., Albuquerque, E. X., et al. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb03519.x · Cited by 138
Self-citationNeuronal nicotinic acetylcholine receptor β‐subunit is coded for by the cDNA clone α4
Whiting, P. J., Esch, F. S., Shimasaki, S., & Lindstrom, J. M. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)80272-7 · Cited by 134
Calcium permeability of nicotinic acetylcholine receptor channels in bovine adrenal chromaffin cells
Zhou, Z., & Neher, E. (1993) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/bf00374879 · Cited by 130
Desensitization of Nicotine‐Stimulated [3H]Dopamine Release from Mouse Striatal Synaptosomes
Grady, S. R., Marks, M. J., & Collins, A. C. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62041390.x · Cited by 126
Rathouz, M., & Berg, D. K. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-11-06935.1994 · Cited by 126
Sacaan, A. I., Dunlop, J. L., & Lloyd, G. K. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)10508-9 · Cited by 123
Araujo, D. M., Lapchak, P. A., Collier, B., & Quirion, R. (1988) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1988.tb04869.x · Cited by 121
Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes
Wilkie, G., Hutson, P. H., Sullivan, J. P., & Wonnacott, S. (1996) · Neurochemical Research · doi:10.1007/bf02532425 · Cited by 103
Self-citationSoliakov, L. S., & Wonnacott, S. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.67010163.x · Cited by 101
Self-citationFeedback control of transmitter release at the neuromuscular junction
Bowman, W. C., Marshall, I. G., Gibb, A. J., & Harborne, A. J. (1988) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(88)90236-2 · Cited by 101
Clarke, P. B. S., Hamill, G. S., Nadi, N. S., Jacobowitz, D. M., & Pert, A. (1986) · The Journal of Comparative Neurology · doi:10.1002/cne.902510311 · Cited by 94
McMahon, L. L., Yoon, K.-W., & Chiappinelli, V. A. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90187-2 · Cited by 89
Quirion, R., Richard, J. W., & Wilson, A. L. (1994) · Synapse · doi:10.1002/syn.890170205 · Cited by 84
Vizi, E. S., & Somogyi, G. T. (1989) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1989.tb11924.x · Cited by 83
Schulz, D. W., & Zigmond, R. E. (1989) · Neuroscience Letters · doi:10.1016/0304-3940(89)90420-5 · Cited by 81
El-Bizri, H., & Clarke, P. B. S. (1994) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1994.tb14749.x · Cited by 79
Clarke, P. B. S. (1993) · Progress in brain research · doi:10.1016/s0079-6123(08)62383-3 · Cited by 78
Anatoxin-a-evoked [3H]dopamine release from rat striatal synaptosomes
Soliakov, L. S., Gallagher, T. C., & Wonnacott, S. (1995) · Neuropharmacology · doi:10.1016/0028-3908(95)00122-m · Cited by 76
Self-citationAcetylcholine Receptors: Too Many Channels, Too Few Functions
Sivilotti, L. G., & Colquhoun, D. (1995) · Science · doi:10.1126/science.7569892 · Cited by 73
Vizi, E. S., Sershen, H. W., BALLA, A., Mike, Á., Windisch, K., Jurányi, Z., & Lajtha, Á. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb17466.x · Cited by 72
Rowell, P. P., & Hillebrand, J. A. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63020561.x · Cited by 70
Yang, X., Criswell, H. E., & Breese, G. R. (1996) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12298-2 · Cited by 69
Wong, E. T., Holstad, S. G., Mennerick, S. J., Hong, S. E., Zorumski, C. F., & Isenberg, K. E. (1995) · Molecular Brain Research · doi:10.1016/0169-328x(94)00189-l · Cited by 68
Locomotor activation and dopamine release produced by nicotine and isoarecolone in rats
Whiteaker, P., Garcha, H. S., Wonnacott, S., & Stolerman, I. P. (1995) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1995.tb16417.x · Cited by 66
Self-citationAgonist pharmacology of the neuronal α7 nicotinic receptor expressed in Xenopus oocytes
Amar, M., Thomas, P., Johnson, C. M., Lunt, G. G., & Wonnacott, S. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)81005-k · Cited by 64
Self-citationWessler, I. K. (1992) · International review of neurobiology · doi:10.1016/s0074-7742(08)60100-2 · Cited by 61
Tian, L., Prior, C., Dempster, J., & Marshall, I. G. (1994) · The Journal of Physiology · doi:10.1113/jphysiol.1994.sp020151 · Cited by 60
Cachelin, A. B., & Rust, G. (1994) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)09865-7 · Cited by 54
Vibat, C. R. T., Lasalde, J. A., McNamee, M. G., & Ochoa, E. L. M. (1995) · Cellular and Molecular Neurobiology · doi:10.1007/bf02071877 · Cited by 51
McMahon, L. L., Yoon, K.-W., & Chiappinelli, V. A. (1994) · Journal of Neurophysiology · doi:10.1152/jn.1994.71.2.826 · Cited by 50
Sacaan, A. I., Menzaghi, F., Dunlop, J. L., Correa, L. D., Whelan, K. T., & Lloyd, G. K. (1996) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12301-x · Cited by 47
Marks, M. J., Bullock, A. E., & Collins, A. C. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)10641-1 · Cited by 33
Ciba Foundation Symposium 152 ‐ The Biology of Nicotine Dependence
(2007) · Novartis Foundation symposium · doi:10.1002/9780470513965 · Cited by 26
Presynaptic Nicotinic Autoreceptors and Heteroreceptors in the CNS
Wonnacott, S., Wilkie, G., Soliakov, L. S., & Whiteaker, P. (1995) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-7445-8_11 · Cited by 19
Self-citationLesion with the neurotoxin AF64A alters hippocampal cholinergic receptor function
Thorne, B., & Potter, P. E. (1995) · Brain Research Bulletin · doi:10.1016/0361-9230(95)00076-q · Cited by 16
Ochoa, E. L. M., & O'Shea, S. M. (1994) · Cellular and Molecular Neurobiology · doi:10.1007/bf02088714 · Cited by 15
Ramcharan, E. J., & Matthews, M. R. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00478-5 · Cited by 13
Impact of α-bungarotoxin on transmitter release at the neuromuscular junction of the rat
Domet, M. A., Webb, C. E., & Wilson, D. F. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)12013-t · Cited by 12
Doležal, V., Schobert, A., & Hertting, G. (1995) · Neurochemical Research · doi:10.1007/bf00969541 · Cited by 7
Nicotine-induced depolarization of cerebral cortical synaptosomes is dependent upon sodium
Hillard, C. J. (1992) · Neuropharmacology · doi:10.1016/0028-3908(92)90129-d · Cited by 6
Research works printed but not linked: 10
- Yang, 1996, J. Pharmacol. Exp. Ther., 276, 482
- Marks, 1995, J. Pharmacol. Exp. Ther., 274, 833
- Marshall, D. et al. Neuropharmacology (in press)
- Sacaan, 1995, J. Pharmacol. Exp. Ther., 274, 224
- Sacaan, 1996, J. Pharmacol. Exp. Ther., 276, 509
- Papke, 1994, Mol. Pharmacol., 45, 142
- Peng, 1994, Mol. Pharmacol., 46, 523
- Flores, 1992, Mol. Pharmacol., 41, 31
- Cachelin, 1994, Mol. Pharmacol., 46, 1168
- Bowman W.C. (1996) in Neuromuscular Transmission (Fundamentals of Anaesthesia and Acute Medicine) (Booij, L.H.D., ed.), pp. 1–27, BMJ Publishing Group
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Mammalian nicotinic acetylcholine receptors: from structure to function
Albuquerque, E. X., Pereira, E. F. R., Alkondon, M., & Rogers, S. W. (2009) · Physiological Reviews · doi:10.1152/physrev.00015.2008 · Cited by 1,724
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Benowitz, N. L. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0809890 · Cited by 1,508
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Metadata
- Authors
- Wonnacott, S.
- Affiliations
- University of Bath (GB)
- Corresponding author
- Wonnacott, Susan
- ORCID
- Wonnacott, Susan
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 1997-02
- Volume
- 20
- Issue
- 2
- Pages
- 92-98
- ISSN
- 0166-2236 (ISSN-L)
- OpenAlex
- W2081391428
- Cited by
- 1,308
- References
- 74
- Citations by year
- 2026: 8 · 2025: 8 · 2024: 15 · 2023: 15 · 2022: 31 · 2021: 16 · 2020: 25 · 2019: 17 · 2018: 25 · 2017: 23 · 2016: 26 · 2015: 36 · 2014: 35 · 2013: 37 · 2012: 22
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Neurosciences (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Keywords
- presynaptic nicotinic acetylcholine receptors, ligand-gated cation channels, neurotransmitter release modulation, presynaptic terminals, receptor pharmacology
- MeSH terms
- Animals, Brain, Receptors, Nicotinic, Presynaptic Terminals, Rats
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