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Other simulations of evolving ecosystems confirm the generative potential of artificial life systems.
“Other simulations of evolving ecosystems confirm the generative potential of artificial life systems [300,314–317].”
From Fundamental constraints to the logic of living systems (2024) · cites this paper as [316]
Cites
The Hypercycle: A principle of natural self-organization
Eigen, M., & Schuster, P. M. (1979) · Cited by 1,906 · see citing works
Cooperation and Competition in the Evolution of ATP-Producing Pathways
Pfeiffer, T., Schuster, S., & Bonhoeffer, S. (2001) · Science · doi:10.1126/science.1058079 · Cited by 1,365 · see citing works
Deleterious mutations and the evolution of sexual reproduction
Kondrashov, A. S. (1988) · Nature · doi:10.1038/336435a0 · Cited by 1,127 · see citing works
Lenski, R. E., & Travisano, M. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.15.6808 · Cited by 1,019 · see citing works
Automatic design and manufacture of robotic lifeforms
Lipson, H., & Pollack, J. B. (2000) · Nature · doi:10.1038/35023115 · Cited by 896 · see citing works
Evolution of high mutation rates in experimental populations of E. coli
Sniegowski, P. D., Gerrish, P. J., & Lenski, R. E. (1997) · Nature · doi:10.1038/42701 · Cited by 879 · see citing works
The fate of competing beneficial mutations in an asexual population
Gerrish, P. J., & Lenski, R. E. (1998) · Genetica · doi:10.1023/a:1017067816551 · Cited by 783 · see citing works
The fate of competing beneficial mutations in an asexual population
Gerrish, P. J., & Lenski, R. E. (1998) · Contemporary issues in genetics and evolution · doi:10.1007/978-94-011-5210-5_12 · Cited by 721 · see citing works
Langton, C. G., Taylor, C., Farmer, D., & Rasmussen, S. (1991) · Cited by 706 · see citing works
Evolution of digital organisms at high mutation rates leads to survival of the flattest
Wilke, C. O., Wang, J. L., Ofria, C., Lenski, R. E., & Adami, C. (2001) · Nature · doi:10.1038/35085569 · Cited by 623 · see citing works
Self-citationEvolution of biological complexity
Adami, C., Ofria, C., & Collier, T. C. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.9.4463 · Cited by 592 · see citing works
Self-citationA pluralist approach to sex and recombination
West, S. A., Lively, & Read (1999) · Journal of Evolutionary Biology · doi:10.1046/j.1420-9101.1999.00119.x · Cited by 544 · see citing works
The population genetics of ecological specialization in evolving Escherichia coli populations
Cooper, V. S., & Lenski, R. E. (2000) · Nature · doi:10.1038/35037572 · Cited by 519 · see citing works
Experimental Tests of the Roles of Adaptation, Chance, and History in Evolution
Travisano, M., Mongold, J. A., Bennett, A. F., & Lenski, R. E. (1995) · Science · doi:10.1126/science.7809610 · Cited by 511 · see citing works
A general model for the evolution of recombination
Barton, N. (1995) · Genetics Research · doi:10.1017/s0016672300033140 · Cited by 425 · see citing works
Test of synergistic interactions among deleterious mutations in bacteria
Elena, S. F., & Lenski, R. E. (1997) · Nature · doi:10.1038/37108 · Cited by 416 · see citing works
Introduction To Artificial Life
Adami, C. (1998) · IEEE Transactions on Evolutionary Computation · doi:10.1109/tevc.1998.738989 · Cited by 404 · see citing works
Self-citationSelection against harmful mutations in large sexual and asexual populations
Kondrashov, A. S. (1982) · Genetics Research · doi:10.1017/s0016672300019194 · Cited by 327 · see citing works
Genome complexity, robustness and genetic interactions in digital organisms
Lenski, R. E., Ofria, C., Collier, T. C., & Adami, C. (1999) · Nature · doi:10.1038/23245 · Cited by 306 · see citing works
Self-citationEvolvability of an RNA virus is determined by its mutational neighbourhood
Burch, C. L., & Chao, L. (2000) · Nature · doi:10.1038/35020564 · Cited by 276 · see citing works
Fitness effects of advantageous mutations in evolving Escherichia coli populations
Imhof, M., & Schlötterer, C. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.3.1113 · Cited by 250 · see citing works
Stationary mutant distributions and evolutionary optimization
Schuster, P., & Swetina, J. (1988) · Bulletin of Mathematical Biology · doi:10.1016/s0092-8240(88)80059-4 · Cited by 202 · see citing works
Efficiency of truncation selection
Crow, J. F., & Kimura, M. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.1.396 · Cited by 201 · see citing works
Rice, S. H. (1998) · Evolution · doi:10.1111/j.1558-5646.1998.tb03690.x · Cited by 200 · see citing works
SELECTIVE MECHANISMS IN BACTERIAPreprint
Atwood, K. C., Schneider, L. K., & Rryan, F. J. (1951) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1951.016.01.026 · Cited by 196 · see citing works
Muller's ratchet under epistatic selection.
Kondrashov, A. S. (1994) · Genetics · doi:10.1093/genetics/136.4.1469 · Cited by 170 · see citing works
Whitlock, M. C., & Bourguet, D. (2000) · Evolution · doi:10.1111/j.0014-3820.2000.tb00709.x · Cited by 147 · see citing works
Quasispecies Theory in Virology
Domingo, E. (2002) · Journal of Virology · doi:10.1128/jvi.76.1.463-465.2002 · Cited by 146 · see citing works
Bedau, M. A., McCaskill, J. S., & Rasmussen, S. (2000) · The MIT Press eBooks · doi:10.7551/mitpress/1432.001.0001 · Cited by 130 · see citing works
Is the Quasispecies Concept Relevant to RNA Viruses?
Holmes, E. C., & Moyá, A. (2002) · Journal of Virology · doi:10.1128/jvi.76.1.460-462.2002 · Cited by 124 · see citing works
The coreworld: Emergence and evolution of cooperative structures in a computational chemistry
Rasmussen, S., Knudsen, C., Feldberg, R., & Hindsholm, M. (1990) · Physica D Nonlinear Phenomena · doi:10.1016/0167-2789(90)90070-6 · Cited by 116 · see citing works
Interaction between directional epistasis and average mutational effects
Wilke, C. O., & Adami, C. (2001) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2001.1690 · Cited by 113 · see citing works
Self-citationSelf-organized criticality in living systems
Adami, C. (1995) · Physics Letters A · doi:10.1016/0375-9601(95)00372-a · Cited by 106 · see citing works
Self-citationFoster, J. A. (2001) · Nature Reviews Genetics · doi:10.1038/35076523 · Cited by 105 · see citing works
Evolution, complexity, entropy and artificial reality
Ray, T. S. (1994) · Physica D: Nonlinear Phenomena · doi:10.1016/0167-2789(94)90286-0 · Cited by 93 · see citing works
An Experimental Test for Synergistic Epistasis and Its Application in Chlamydomonas
de Visser, J. A. G. M., Hoekstra, R. F., & ENDE, H. V. D. (1997) · Genetics · doi:10.1093/genetics/145.3.815 · Cited by 86 · see citing works
Genetic measurement theory of epistatic effects
Wagner, G. P., Laubichler, M. D., & Bagheri, H. C. (1998) · Contemporary issues in genetics and evolution · doi:10.1007/978-94-011-5210-5_43 · Cited by 75 · see citing works
McRobb, L. S., & Ferenci, T. (2000) · Genetics · doi:10.1093/genetics/156.4.1493 · Cited by 67 · see citing works
Little Evidence for Synergism Among Deleterious Mutations in a Nonsegmented RNA Virus
Elena, S. F. (1999) · Journal of Molecular Evolution · doi:10.1007/pl00000082 · Cited by 63 · see citing works
EFFECT OF DELETERIOUS MUTATION-ACCUMULATION ON THE FITNESS OF RNA BACTERIOPHAGE MS2
de la Peña, M., Elena, S. F., & Moyá, A. (2000) · Evolution · doi:10.1554/0014-3820(2000)054[0686:eodmao]2.0.co;2 · Cited by 58 · see citing works
Smith, J. M. (1992) · Nature · doi:10.1038/355772a0 · Cited by 57 · see citing works
Testing for Epistasis Between Deleterious Mutations
West, S. A., Peters, A. D., & Barton, N. (1998) · Genetics · doi:10.1093/genetics/149.1.435 · Cited by 57 · see citing works
Genetic measurement theory of epistatic effects
Wagner, G. P., Laubichler, M. D., & Bagheri, H. C. (1998) · Genetica · doi:10.1023/a:1017088321094 · Cited by 57 · see citing works
A Test for Epistasis Among Induced Mutations in Caenorhabditis elegans
Peters, A. D., & Keightley, P. D. (2000) · Genetics · doi:10.1093/genetics/156.4.1635 · Cited by 53 · see citing works
Microevolution in an Electronic Microcosm
Yedid, G., & Bell, G. (2001) · The American Naturalist · doi:10.1086/319928 · Cited by 50 · see citing works
The spontaneous generation of digital “Life”
Pargellis, A. N. (1996) · Physica D Nonlinear Phenomena · doi:10.1016/0167-2789(95)00268-5 · Cited by 41 · see citing works
Wloch, D. M., Borts, R. H., & Korona, R. (2001) · Journal of Evolutionary Biology · doi:10.1046/j.1420-9101.2001.00267.x · Cited by 38 · see citing works
Synergistic epistasis between loci affecting fitness: evidence in plants and fungi
de Visser, J. A. G. M., & Hoekstra, R. F. (1998) · Genetics Research · doi:10.1017/s0016672397003091 · Cited by 35 · see citing works
Soluble Model for the Accumulation of Mutations in Asexual Populations
Colato, A., & Fontanari, J. F. (2001) · Physical Review Letters · doi:10.1103/physrevlett.87.238102 · Cited by 26 · see citing works
Maternal Effects in Molecular Evolution
Wilke, C. O. (2002) · Physical Review Letters · doi:10.1103/physrevlett.88.078101 · Cited by 17 · see citing works
Self-citationEvolution of Differentiated Expression Patterns in Digital Organisms
Ofria, C., Adami, C., Collier, T. C., & Hsu, G. K. (1999) · Lecture notes in computer science · doi:10.1007/3-540-48304-7_19 · Cited by 15 · see citing works
Self-citationAB INITIO MODELING OF ECOSYSTEMS WITH ARTIFICIAL LIFE
Adami, C. (2002) · Natural Resource Modeling · doi:10.1111/j.1939-7445.2002.tb00083.x · Cited by 14 · see citing works
Self-citationIntroduction to Artificial Life
Gelepithis, P. A. M. (1999) · AI & Society · doi:10.1007/bf01205990 · Cited by 7 · see citing works
Influence of Chance, History and Adaptation on Evolution in Digitalia
Wagenaar, D. A., & Adami, C. (2000) · The MIT Press eBooks · doi:10.7551/mitpress/1432.003.0029 · Cited by 7 · see citing works
Self-citation
Flagged first, then by citations
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Sorted by citations
The evolutionary origin of complex features
Lenski, R. E., Ofria, C., Pennock, R. T., & Adami, C. (2003) · Nature · doi:10.1038/nature01568 · Cited by 754 · see citing works
Self-citationRobustness can evolve gradually in complex regulatory gene networks with varying topology
Ciliberti, S., Martin, O. C., & Wagner, A. (2007) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0030015 · Cited by 390 · see citing works
Adami, C. (2002) · BioEssays · doi:10.1002/bies.10192 · Cited by 397 · see citing works
Self-citationThe population genetics and evolutionary epidemiology of RNA viruses
Moyá, A., Holmes, E. C., & Gónzález‐Candelas, F. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro863 · Cited by 389 · see citing works
Avida: A Software Platform for Research in Computational Evolutionary Biology
Ofria, C., & Wilke, C. O. (2004) · Artificial Life · doi:10.1162/106454604773563612 · Cited by 378 · see citing works
Self-citationSimulation as experiment: a philosophical reassessment for biological modeling
Peck, S. L. (2004) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2004.07.019 · Cited by 300 · see citing works
Fundamentals of natural computing: an overview
DECASTRO, L. (2006) · Physics of Life Reviews · doi:10.1016/j.plrev.2006.10.002 · Cited by 295 · see citing works
Life is Physics: Evolution as a Collective Phenomenon Far From Equilibrium
Goldenfeld, N. D., & Woese, C. R. (2011) · Annual Review of Condensed Matter Physics · doi:10.1146/annurev-conmatphys-062910-140509 · Cited by 278 · see citing works
A Life‐History Perspective on Short‐ and Long‐Term Consequences of Compensatory Growth
Mangel, M., & Munch, S. B. (2005) · The American Naturalist · doi:10.1086/444439 · Cited by 245 · see citing works
Towards an evolutionary ecology of life in soil
Crawford, J. W., HARRIS, J., Ritz, K., & Young, I. M. (2004) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2004.11.014 · Cited by 165 · see citing works
Digital genetics: unravelling the genetic basis of evolution
Adami, C. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1771 · Cited by 136 · see citing works
Self-citationEvolution of mutational robustness
Wilke, C. O., & Adami, C. (2003) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(02)00307-x · Cited by 136 · see citing works
Self-citationAdaptive Radiation from Resource Competition in Digital Organisms
Chow, S. S., Wilke, C. O., Ofria, C., Lenski, R. E., & Adami, C. (2004) · Science · doi:10.1126/science.1096307 · Cited by 132 · see citing works
Self-citationSexual reproduction reshapes the genetic architecture of digital organisms
Misevic, D., Ofria, C., & Lenski, R. E. (2005) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2005.3338 · Cited by 120 · see citing works
EFFECTS OF POPULATION SIZE AND MUTATION RATE ON THE EVOLUTION OF MUTATIONAL ROBUSTNESS
Elena, S. F., Wilke, C. O., Ofria, C., & Lenski, R. E. (2007) · Evolution · doi:10.1111/j.1558-5646.2007.00064.x · Cited by 73 · see citing works
Self-citationSelective pressures on genomes in molecular evolution
Ofria, C., Adami, C., & Collier, T. C. (2003) · Journal of Theoretical Biology · doi:10.1016/s0022-5193(03)00062-6 · Cited by 60 · see citing works
Self-citationEcological Specialization and Adaptive Decay in Digital Organisms
Ostrowski, E. A., Ofria, C., & Lenski, R. E. (2006) · The American Naturalist · doi:10.1086/510211 · Cited by 50 · see citing works
Adaptive Phenotypic Plasticity Stabilizes Evolution in Fluctuating Environments
Lalejini, A., Ferguson, A. J., Grant, N. A., & Ofria, C. (2021) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2021.715381 · Cited by 49 · see citing works
Speth, E. B., Long, T. M., Pennock, R. T., & Ebert‐May, D. (2009) · Evolution Education and Outreach · doi:10.1007/s12052-009-0154-z · Cited by 49 · see citing works
Dorn, E. D., Nealson, K. H., & Adami, C. (2011) · Journal of Molecular Evolution · doi:10.1007/s00239-011-9429-4 · Cited by 52 · see citing works
Self-citationde Vladar, H. P., Mauro Santos, A., & Szathmáry, E. (2017) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2017.01.008 · Cited by 42 · see citing works
Modeling post-depositional mixing of archaeological deposits
Brantingham, P. J., Surovell, T. A., & Waguespack, N. M. (2007) · Journal of Anthropological Archaeology · doi:10.1016/j.jaa.2007.08.003 · Cited by 40 · see citing works
Sequence complexity in Darwinian evolution
Adami, C. (2002) · Complexity · doi:10.1002/cplx.10071 · Cited by 40 · see citing works
Self-citationAdaptation in Simple and Complex Fitness Landscapes
Jain, K., & Krug, J. (2007) · Biological and medical physics series · doi:10.1007/978-3-540-35306-5_14 · Cited by 35 · see citing works
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Solé, R., Kempes, C. P., Corominas-Murtra, B., De Domenico, M., Kolchinsky, A., Lachmann, M., Libby, E., Saavedra, S., Smith, E., & Wolpert, D. (2024) · Interface Focus · doi:10.1098/rsfs.2024.0010 · Cited by 34 · see citing works
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Adami, C. (2015) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-015-9439-0 · Cited by 31 · see citing works
Self-citationDigital natures: New ontologies, new politics?
Luque‐Ayala, A., Machen, R., & Nost, E. (2024) · Digital Geography and Society · doi:10.1016/j.diggeo.2024.100081 · Cited by 27 · see citing works
Ofria, C., Bryson, D., & Wilke, C. O. (2009) · Springer eBooks · doi:10.1007/978-1-84882-285-6_1 · Cited by 26 · see citing works
Self-citationYedid, G., Ofria, C., & Lenski, R. E. (2008) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2008.01564.x · Cited by 25 · see citing works
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Comas, I., Moyá, A., & Gónzález‐Candelas, F. (2005) · BMC Evolutionary Biology · doi:10.1186/1471-2148-5-5 · Cited by 25 · see citing works
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Johnson, T. J., & Wilke, C. O. (2004) · Artificial Life · doi:10.1162/106454604773563577 · Cited by 24 · see citing works
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LaBar, T., & Adami, C. (2016) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005066 · Cited by 24 · see citing works
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Macal, C. M. (2009) · Encyclopedia of Complexity and Systems Science · doi:10.1007/978-0-387-30440-3_7 · Cited by 24 · see citing works
Experiments with Digital Organisms on the Origin and Maintenance of Sex in Changing Environments
Misevic, D., Ofria, C., & Lenski, R. E. (2010) · Journal of Heredity · doi:10.1093/jhered/esq017 · Cited by 23 · see citing works
Lalejini, A., Dolson, E. L., Vostinar, A. E., & Zaman, L. (2022) · eLife · doi:10.7554/elife.79665 · Cited by 22 · see citing works
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NORTH, M. J., & Macal, C. M. (2006) · Springer eBooks · doi:10.1007/1-84628-214-4_6 · Cited by 21 · see citing works
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Guttenberg, N., & Goldenfeld, N. D. (2008) · Physical Review Letters · doi:10.1103/physrevlett.100.058102 · Cited by 20 · see citing works
O’Donnell, D. R., Fish, J. A., Parigi, A. A., Dworkin, I. M., & Wagner, A. P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100163 · Cited by 20 · see citing works
Prospects of a Computational Origin of Life Endeavor
Shenhav, B., & Lancet, D. (2003) · Origins of Life and Evolution of Biospheres · doi:10.1023/b:orig.0000009839.53483.42 · Cited by 17 · see citing works
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Wilke, C. O., Forster, R., & Novella, I. S. (2006) · Springer eBooks · doi:10.1007/3-540-26397-7_2 · Cited by 17 · see citing works
Self-citationO’Neill, B. (2003) · PLoS Biology · doi:10.1371/journal.pbio.0000018 · Cited by 16 · see citing works
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Adami, C., & Wilke, C. O. (2004) · Artificial Life · doi:10.1162/106454604773563540 · Cited by 16 · see citing works
Self-citationFortuna, M. A., Zaman, L., Wagner, A., & Bascompte, J. (2017) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2016.0431 · Cited by 15 · see citing works
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Peacor, S. D., Stefano Allesina, A., Riolo, R., & Hunter, T. S. (2007) · Ecological Modelling · doi:10.1016/j.ecolmodel.2007.01.026 · Cited by 14 · see citing works
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Shao, J., & Ray, T. S. (2010) · Cited by 13 · see citing works
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Egri-Nagy, A., & Nehaniv, C. L. (2003) · Lecture notes in computer science · doi:10.1007/978-3-540-39432-7_26 · Cited by 13 · see citing works
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Li, Y., & Wilke, C. O. (2004) · Artificial Life · doi:10.1162/106454604773563559 · Cited by 13 · see citing works
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Liu, Y., & Sumpter, D. J. T. (2017) · Journal of The Royal Society Interface · doi:10.1098/rsif.2016.0816 · Cited by 11 · see citing works
Banzhaf, W., & Hu, T. (2019) · Oxford University Press eBooks · doi:10.1093/obo/9780199941728-0122 · Cited by 11 · see citing works
Maruyama, H. (2013) · International Conference on Dependable Systems and Networks workshops · doi:10.1109/dsnw.2013.6615532 · Cited by 8 · see citing works
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Lenski, R. E. (2004) · Cited by 7 · see citing works
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Scientifi c Fictions as Rules of Inference
Suárez, M. (2008) · Routledge eBooks · doi:10.4324/9780203890103-14 · Cited by 6 · see citing works
Maruyama, H., & Minami, K. (2013) · Innovation and supply chain management · doi:10.14327/iscm.7.105 · Cited by 5 · see citing works
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Wilke, C. O. (2003) · Lecture notes in computer science · doi:10.1007/978-3-540-39432-7_43 · Cited by 5 · see citing works
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Ofria, C., & Wilke, C. O. (2005) · Springer eBooks · doi:10.1007/1-84628-214-4_1 · Cited by 5 · see citing works
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Hang, D., Ofria, C., Schmidt, T. M., & Torng, E. K. (2003) · Lecture notes in computer science · doi:10.1007/3-540-45105-6_2 · Cited by 5 · see citing works
PHYSICAL COMPLEXITY AND COGNITIVE EVOLUTION
Jedlička, P. (2007) · doi:10.1142/9789812707420_0014 · Cited by 6 · see citing works
The Scope of Evolutionary Thinking
Reydon, T. A. C. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009181839 · Cited by 4 · see citing works
Evaluating resilience strategies based on an evolutionary multi-agent system
Minami, K., Tanjo, T., & Maruyama, H. (2013) · IEEE International Conference on Cybernetics and Computational Intelligence (CyberneticsCom) · doi:10.1109/cyberneticscom.2013.6865776 · Cited by 4 · see citing works
Ling, M. H. (2017) · MOJ Proteomics & Bioinformatics · doi:10.15406/mojpb.2017.06.00193 · Cited by 3 · see citing works
Simulating Evolution’s First Steps
Hutton, T. J. (2003) · Lecture notes in computer science · doi:10.1007/978-3-540-39432-7_6 · Cited by 4 · see citing works
Exploring Evolved Multicellular Life Histories in a Open-Ended Digital Evolution System
Moreno, M. A., & Ofria, C. (2022) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2022.750837 · Cited by 5 · see citing works
Universal biosignatures for the detection of life
Dorn, E. D. (2005) · CaltechTHESIS (California Institute of Technology) · doi:10.7907/08b9-8q96 · Cited by 4 · see citing works
Parke, E. C. (2023) · doi:10.1002/9781119555568.ch2 · Cited by 4 · see citing works
The Genetic Coding Style of Digital Organisms
Gerlee, P., & Lundh, T. (2005) · Lecture notes in computer science · doi:10.1007/11553090_86 · Cited by 3 · see citing works
The Role of Pleiotropy and Epistasis on Evolvability and Robustness in a Two-Peak Fitness Landscape
Mehra, P., & Hintze, A. (2024) · Biology · doi:10.3390/biology13121003 · Cited by 2 · see citing works
Cost of resistance to parasites in digital organisms
Kraaijeveld, A. R. (2007) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2007.01319.x · Cited by 2 · see citing works
Nutrient Availability Impacts Intracellular Metabolic Profiles in Digital Organisms
Kannan, K. S. S., Patil, T., Vij, R., Loh, B. J., & Ling, M. H. (2022) · ACTA SCIENTIFIC MICROBIOLOGY · doi:10.31080/asmi.2022.05.1076 · Cited by 1 · see citing works
Virtual Worlds: The Role of Simulation in Ecology
Green, D. G., Klomp, N. I., Rimmington, G., & Sadedin, S. (2020) · Landscape series · doi:10.1007/978-3-030-46773-9_9 · Cited by 2 · see citing works
Simple rules for simple models
Messé, A., Hilgetag, C. C., & Hütt, M. ‐. (2025) · Physics of Life Reviews · doi:10.1016/j.plrev.2025.10.006 · Cited by 1 · see citing works
Biological Complexity and Cognitive Evolution
Jedlička, P., Varchola, J., & Betinsky, J. (2026) · Biological Theory · doi:10.1007/s13752-026-00532-z · Cited by 1 · see citing works
Evaluating the sustainability of an ecological system based on evolutionary multi-agent simulations
Minami, K., Legaspi, R., Tanjo, T., Maruyama, H., & Yamagata, Y. (2014) · Cited by 1 · see citing works
Agent Based Modeling and Artificial Life
Macal, C. M. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1800-9_3 · Cited by 1 · see citing works
Genetic distance in sequence space of evolving populations
Manffra, E. F., Kantz, H., & Ragwitz, M. (2003) · Complexity · doi:10.1002/cplx.10088
Self-protection maintains diversity of artificial self-replicators evolving in cellular automata
Sayama, H. (2003) · NASA/DoD Conference on Evolvable Hardware · doi:10.1109/eh.2003.1217673
Thesis Speciation in Digital Organisms
Chow, S. S., & Chow, S. S. (2005)
Personal Informatics and Evolution in the Digital Universe
John, J. L. (2014) · Synthese Library/Synthese library · doi:10.1007/978-3-319-07121-3_13
Host-symbiont coevolution in digital and microbial systems
Zaman, L. (2014) · Michigan State University Libraries · doi:10.25335/m5n39d
Digital Evolution in Time-Dependent Fitness
Li, Y., & Wilke, C. O. (2004)
Self-citationComplexity of a Phenotype with Greater Plasticity for Digital Evolvable HardwarePreprint
Salvadeo, P. A., Veca, A., & Castro-Lopez, R. (2017)
The epistemic role of fiction in scientific models
Katic, A. (2020) · Theoria Beograd · doi:10.2298/theo2003005k
Experimenting the Unexperimentable With Digital Organisms
Maitra, A., Lim, J. J. H., Ho, C. J. Y., Tang, A. Y., Teo, W., Alejado, E. L. C., & Ling, M. H. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95502-7.00069-5
From valleys to peaks: The role of evolvability in fitness landscape navigation.
Mehra, P., & Hintze, A. (2025) · PubMed Central · doi:10.1093/pnasnexus/pgaf221
- Authors
- Wilke, C. O., & Adami, C.
- Affiliations
- California Institute of Technology (US)
- Corresponding author
- Wilke, Claus O.
- Venue
- Trends in Ecology & Evolution
- Publisher
- Elsevier BV
- Published
- 2002-11
- Volume
- 17
- Issue
- 11
- Pages
- 528-532
- ISSN
- 0169-5347 (ISSN-L)
- OpenAlex
- W2159830634
- Cited by
- 103
- References
- 54
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 4 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 4 · 2019: 1 · 2017: 6 · 2016: 1 · 2015: 2 · 2014: 5 · 2013: 4
- FWCI
- 1.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Ecology & Evolution (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Physical Sciences › Computer Science › Artificial Intelligence › Evolutionary Algorithms and Applications
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Keywords
- digital organisms, artificial life, self-replicating programs, computer viruses, selective breeding, adaptive evolution, complexity growth, epistasis
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