The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
The Women’s Health Initiative Memory Study (WHIMS)
Open accessAbstract
Evidence from animal, human cross-sectional, case-control, and prospective studies indicate that hormone replacement therapy (HRT) is a promising treatment to delay the onset of symptoms of dementia. The Women's Health Initiative Memory Study (WHIMS) is the first double-masked, randomized, placebo-controlled, long-term clinical trial designed to test the hypothesis that HRT reduces the incidence of all-cause dementia in women aged 65 and older. WHIMS, an ancillary study to the Women's Health Initiative (WHI) funded by the National Institutes of Health, will recruit a subgroup of women aged 65 and older from among those enrolling in the HRT trial of the WHI. The WHI clinical centers and 10 affiliated satellites plan to enroll approximately 8300 women into WHIMS over a 2-year period. Participants will be followed annually for 6 years, receiving cognitive assessments via the Modified Mini-Mental State (3MS) Examination. Women who screen positively for cognitive impairment on the basis of an educational and age-adjusted 3MS cutpoint proceed to more extensive neuropsychological testing and neurologic evaluation. Each woman suspected to have dementia then undergoes a series of laboratory tests that confirm the clinical diagnosis and classify the type of dementia. WHIMS is designed to provide more than 80% statistical power to detect a 40% reduction in the rate of all-cause dementia, an effect that could have profound public health implications for older women's health and functioning.
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Cites
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Regression Models and Life-Tables
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Cited by
Shumaker, S. A., Legault, C., Rapp, S. R., Thal, L., Wallace, R. B., Ockene, J. K., Hendrix, S. L., Jones III, B. N., Assaf, A. R., Jackson, R. D., et al. (2003) · JAMA · doi:10.1001/jama.289.20.2651 · Cited by 2,178
Self-citationEstrogen and cognitive functioning in women
Sherwin, B. B. (2003) · Endocrine Reviews · doi:10.1210/er.2001-0016 · Cited by 560
Reiman, E. M., Caselli, R. J., Chen, K., Alexander, G. E., Bandy, D., & Frost, J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061509598 · Cited by 467
Effects of Combination Estrogen Plus Progestin Hormone Treatment on Cognition and Affect
Resnick, S. M., Maki, P. M., Rapp, S. R., Espeland, M. A., Brunner, R., Coker, L. H., Granek, I. A., Hogan, P., Ockene, J. K., & Shumaker, S. A. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2097 · Cited by 310
Self-citationLongitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognition
Maki, P. M., & Resnick, S. M. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00123-8 · Cited by 289
Metadata
- Authors
- Shumaker, S. A., Reboussin, B. A., Espeland, M. A., Rapp, S. R., McBee, W. L., Dailey, M., Bowen, D., Terrell, T., & Jones, B. N.
- Venue
- Controlled Clinical Trials
- Publisher
- Elsevier BV
- Published
- 1998-12
- Volume
- 19
- Issue
- 6
- Pages
- 604-621
- ISSN
- 0197-2456 (ISSN-L)
- OpenAlex
- W1487246579
- Cited by
- 321
- References
- 62
- FWCI
- 7.44
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Shumaker, S. A., Reboussin, B. A., Espeland, M. A., Rapp, S. R., McBee, W. L., Dailey, M., Bowen, D., Terrell, T., & Jones, B. N. (1998). The Women’s Health Initiative Memory Study (WHIMS). Controlled Clinical Trials. https://doi.org/10.1016/s0197-2456(98)00038-5
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
