The DOI matches its Crossref record.
Hypothalamic orexin-A binding sites are downregulated by chronic nicotine treatment in the rat
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“However, the hypothalamic density of the NPY Y1 receptor is reduced by chronic nicotine treatment (Kane et al., 2001).”
From Cigarette Smoking and Brain Regulation of Energy Homeostasis (2012) · cites this paper as Kane et al., 2001
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 20
- Allen, 1983, Neuropeptide Y distribution in the rat brain, Science, 221, 877, 10.1126/science.6136091 · DOI
- Chansel, 1994, Differential regulation of angiotensin II and losartan binding sites in glomeruli and mesangial cells, Am. J. Physiol., 266, F384
- de Lecea, 1998, The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity, Proc. Natl. Acad. Sci. USA, 95, 322, 10.1073/pnas.95.1.322 · DOI · Paper page
- Di Scala-Guenot, 1995, Downregulation of the oxytocin receptor on cultured astroglial cells, Am. J. Physiol., 268, C413, 10.1152/ajpcell.1995.268.2.C413 · DOI
- Grady, 1997, Turning off the signal: mechanisms that attenuate signaling by G protein-coupled receptors, Am. J. Physiol., 273, G586
- Hiremagalur, 1995, Nicotine elicits changes in expression of adrenal catecholamine biosynthetic enzymes, neuropeptide Y and immediate early genes by injection but not continuous administration, Brain Res. Mol. Brain Res., 32, 109, 10.1016/0169-328X(95)00068-4 · DOI
- Jam, 2000, Evidence that NPY Y1 receptors are involved in stimulation of feeding by orexins (hypocretins) in sated rats, Regul. Pept., 87, 19, 10.1016/S0167-0115(99)00102-0 · DOI
- Kane, 2000, Nicotine up-regulates expression of orexin and its receptors in rat brain, Endocrinology, 141, 3623, 10.1210/en.141.10.3623 · DOI
- Kane, 2000, Sensitivity of orexin-A binding to phospholipase C inhibitors, neuropeptide Y, and secretin, Biochem. Biophys. Res. Commun., 272, 959, 10.1006/bbrc.2000.2880 · DOI
- Kastin, 1999, Nonsaturable entry of neuropeptide Y into brain, Am. J. Physiol., 276, E479
- Kastin, 1999, Orexin A but not orexin B rapidly enters brain from blood by simple diffusion, J. Pharmacol. Exp. Ther., 289, 219
- Li, 2000, Nicotine administration enhances NPY expression in the rat hypothalamus, Brain Res., 867, 157, 10.1016/S0006-8993(00)02283-6 · DOI
- Li, 2001, Regulation of feeding and feeding-associated peptides and receptors by nicotine, Mol. Neurobiol.
- Mondal, 1999, Characterization of orexin-A and orexin-B in the microdissected rat brain nuclei and their contents in two obese rat models, Neurosci. Lett., 273, 45, 10.1016/S0304-3940(99)00624-2 · DOI
- Parker, 1998, Characterization of G-protein and phospholipase C - coupled agonist binding to the Y1 neuropeptide Y receptor in rat brain. Sensitivity to G-protein activators and inhibitors and to inhibitors of phospholipase C, J. Pharmacol. Exp. Ther., 286, 1
- Parker, 2000, FMRFamides exert a unique modulation of rodent pancreatic polypeptide sensitive neuropeptide Y (NPY) receptors, Can. J. Physiol. Pharmacol., 78, 150, 10.1139/y99-126 · DOI
- Parker, 2001, Decreased neuropeptide Y (NPY) Y1 receptors in hypothalamus of rats treated with nicotine: evidence for downregulation of a specific population of sites, Brain Res.
- Sakurai, 1998, Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior, Cell, 92, 573, 10.1016/S0092-8674(00)80949-6 · DOI · Paper page
- Smart, 1999, Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR, Br. J. Pharmacol., 128, 1, 10.1038/sj.bjp.0702780 · DOI
- Yamanaka, 1999, Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight, Brain Res., 849, 248, 10.1016/S0006-8993(99)01905-8 · DOI
Cited by
Smoking cessation and weight gain
Filozof, C., Fernández Pinilla, M. C., & Fernández‐Cruz, A. (2004) · Obesity Reviews · doi:10.1111/j.1467-789x.2004.00131.x · Cited by 519
The dorsomedial hypothalamic nucleus and its role in ingestive behavior and body weight regulation
Bellinger, L. L., & Bernardis, L. L. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(02)00756-4 · Cited by 228
Multiple roles for orexin/hypocretin in addiction
Mahler, S. V., Smith, R. J., Moorman, D. E., Sartor, G. C., & Aston-Jones, G. (2012) · Progress in Brain Research · doi:10.1016/b978-0-444-59489-1.00007-0 · Cited by 215
Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse
Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148
The role of neuropeptide Y (NPY) in alcohol and drug abuse disorders
Robinson, S. L., & Thiele, T. E. (2017) · International Review of Neurobiology · doi:10.1016/bs.irn.2017.06.005 · Cited by 75
Metadata
- Authors
- Kane, J. K., Parker, S. L., & Li, M. D.
- Venue
- Neuroscience Letters
- Publisher
- Elsevier BV
- Published
- 2001-01
- Volume
- 298
- Issue
- 1
- Pages
- 1-4
- ISSN
- 0304-3940
- Cited by
- 54
- References
- 0
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Hypothalamic orexin-A binding sites are downregulated by chronic nicotine treatment in the rat. https://app.cochat.ai/papers/10.1016/s0304-3940(00)01730-4
- The paper
- Kane, J. K., Parker, S. L., & Li, M. D. (2001). Hypothalamic orexin-A binding sites are downregulated by chronic nicotine treatment in the rat. Neuroscience Letters. https://doi.org/10.1016/s0304-3940(00)01730-4
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
