The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Altered central sensorimotor processing in patients with complex regional pain syndrome
Abstract
Alterations in tactile sensitivity are common in patients with chronic pain. Recent brain imaging studies have indicated that brain areas activated by acute experimental pain partly overlap with areas processing innocuous tactile stimuli. However, the possible effect of chronic pain on central tactile processing has remained unclear. We have examined, both clinically and with whole-head magnetoencephalography, six patients suffering from complex regional pain syndrome (CRPS) of the upper limb. The cortical somatosensory responses were elicited by tactile stimuli applied to the fingertips and the reactivity of spontaneous brain oscillations was monitored as well. Tactile stimulation of the index finger elicited an initial activation at 65 ms in the contralateral SI cortex, followed by activation of the ipsi- and contralateral SII cortices at about 130 ms. The SI responses were 25-55% stronger to stimulation of the painful than the healthy side. The distance between SI representations of thumb and little finger was significantly shorter in the hemisphere contralateral than ipsilateral to the painful upper limb. In addition, reactivity of the 20-Hz motor cortex rhythm to tactile stimuli was altered in the CRPS patients, suggesting modified inhibition of the motor cortex. These results imply that chronic pain may alter central tactile and motor processing.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hämäläinen, M., Hari, R., Ilmoniemi, R. J., Knuutila, J., & Lounasmaa, O. V. (1993) · Reviews of Modern Physics · doi:10.1103/revmodphys.65.413 · Cited by 4,684
Self-citationHuskisson, E. C. (1974) · The Lancet · doi:10.1016/s0140-6736(74)90884-8 · Cited by 4,522
Increased Cortical Representation of the Fingers of the Left Hand in String Players
Elbert, T., Pantev, C., Wienbruch, C., Rockstroh, B., & Taub, E. (1995) · Science · doi:10.1126/science.270.5234.305 · Cited by 2,054
Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation
Flor, H., Elbert, T., Knecht, S., Wienbruch, C., Pantev, C., Birbaumers, N., Larbig, W., & Taub, E. (1995) · Nature · doi:10.1038/375482a0 · Cited by 1,845
Somatosensory cortical map changes following digit amputation in adult monkeys
Merzenich, M. M., Nelson, R. J., Stryker, M. P., Cynader, M. S., Schoppmann, A., & Zook, J. M. (1984) · Journal of Comparative Neurology · doi:10.1002/cne.902240408 · Cited by 1,328
Reflex sympathetic dystrophy: changing concepts and taxonomy
Stanton-Hicks, M., Jänig, W., Hassenbusch, S., Haddox, J. D., Boas, R., & Wilson, P. (1995) · Pain · doi:10.1016/0304-3959(95)00110-e · Cited by 1,109
The cortical representation of pain
Treede, R.-D., Kenshalo, D. R., Gracely, R. H., & Jones, A. K. P. (1999) · Pain · doi:10.1016/s0304-3959(98)00184-5 · Cited by 1,077
Multiple Representations of Pain in Human Cerebral Cortex
Talbot, J. D., Marrett, S., Evans, A. C., Meyer, E., Bushnell, M. C., & Duncan, G. H. (1991) · Science · doi:10.1126/science.2003220 · Cited by 971
Spatiotemporal characteristics of sensorimotor neuromagnetic rhythms related to thumb movement
Salmelin, R., & Hari, R. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90263-1 · Cited by 794
Self-citationExtensive reorganization of primary somatosensory cortex in chronic back pain patients
Flor, H., Braun, C., Elbert, T., & Birbaumer, N. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)13441-3 · Cited by 713
Cited by
Moseley, L. G. (2004) · Pain · doi:10.1016/j.pain.2004.01.006 · Cited by 681
Transcranial magnetic stimulation highlights the sensorimotor side of empathy for pain.
Avenanti, A., Bueti, D., Galati, G., & Aglioti, S. M. (2005) · Nature Neuroscience · doi:10.1038/nn1481 · Cited by 615
Patterns of cortical reorganization in complex regional pain syndrome
Maihöfner, C., Handwerker, H. O., Neundörfer, B., & Birklein, F. (2003) · Neurology · doi:10.1212/01.wnl.0000098939.02752.8e · Cited by 608
Graded motor imagery for pathologic pain: A randomized controlled trial
Moseley, G. L. (2006) · Neurology · doi:10.1212/01.wnl.0000249112.56935.32 · Cited by 608
Cortical reorganization during recovery from complex regional pain syndrome
Maihöfner, C., Handwerker, H. O., Neundörfer, B., & Birklein, F. (2004) · Neurology · doi:10.1212/01.wnl.0000134661.46658.b0 · Cited by 469
Metadata
- Authors
- Juottonen, K., Gockel, M., Silén, T., Hurri, H., Hari, R., & Forss, N.
- Venue
- Pain
- Published
- 2002-08
- Volume
- 98
- Issue
- 3
- Pages
- 315-323
- ISSN
- 0304-3959 (ISSN-L)
- OpenAlex
- W2045432647
- Cited by
- 366
- References
- 42
- FWCI
- 19.08
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Altered central sensorimotor processing in patients with complex regional pain syndrome. https://app.cochat.ai/papers/10.1016/s0304-3959(02)00119-7
- The paper
- Juottonen, K., Gockel, M., Silén, T., Hurri, H., Hari, R., & Forss, N. (2002). Altered central sensorimotor processing in patients with complex regional pain syndrome. Pain. https://doi.org/10.1016/s0304-3959(02)00119-7
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
