The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
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Cites
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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
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Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck
Brizel, D. M., Sibley, G. S., Prosnitz, L. R., Scher, R. L., & Dewhirst, M. W. (1997) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(97)00101-6 · Cited by 1,068
Self-citationNordsmark, M., Overgaard, M., & Overgaard, J. (1996) · Radiotherapy and Oncology · doi:10.1016/s0167-8140(96)91811-3 · Cited by 942
Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix
Höckel, M., Knoop, C., Schlenger, K., Vorndran, B., Bauβnann, E., Mitze, M., Knapstein, P. G., & Vaupel, P. (1993) · Radiotherapy and Oncology · doi:10.1016/0167-8140(93)90025-4 · Cited by 809
Oxygenation predicts radiation response and survival in patients with cervix cancer
Fyles, A. W., Milosevic, M., Wong, R., Kavanagh, M.-C., Pintilie, M., Sun, A., Chapman, W., Levin, W., Manchul, L., Keane, T. J., et al. (1998) · Radiotherapy and Oncology · doi:10.1016/s0167-8140(98)00044-9 · Cited by 597
Cited by
Why Do Cancers Have High Aerobic Glycolysis?
Gatenby, R. A., & Gillies, R. J. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1478 · Cited by 4,784
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Sonveaux, P., Végran, F., Schroeder, T., Wergin, M. C., Verrax, J., Rabbani, Z. N., De Saedeleer, C. J., Kennedy, K. M., Diepart, C., Jordan, B. F., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci36843 · Cited by 1,624
Self-citationThe Science and Translation of Lactate Shuttle Theory
Brooks, G. A. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.03.008 · Cited by 1,486
Acidic extracellular microenvironment and cancer
Kato, Y., Ozawa, S., Miyamoto, C., Maehata, Y., Suzuki, A., Maeda, T., & Baba, Y. (2013) · Cancer Cell International · doi:10.1186/1475-2867-13-89 · Cited by 1,300
Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches
de la Cruz-López, K. G., Castro-Muñoz, L. J., Reyes-Hernández, D. O., García-Carrancá, A., & Manzo-Merino, J. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.01143 · Cited by 940
“It has been shown that high concentrations of lactate in biopsies of cervical, lung, head and neck, colorectal and breast cancers are associated with an increased risk for developing metastasis, and such levels of lactate indicate a bad prognosis for survival in cancer patients (30, 31, 35, 167) (Table 1).”
Background
Metadata
- Authors
- Brizel, D. M., Schroeder, T., Scher, R. L., Walenta, S., Clough, R. W., Dewhirst, M. W., & Mueller-Klieser, W.
- Venue
- International Journal of Radiation Oncology*Biology*Physics
- Publisher
- Elsevier BV
- Published
- 2001-10
- Volume
- 51
- Issue
- 2
- Pages
- 349-353
- ISSN
- 0360-3016 (ISSN-L)
- OpenAlex
- W2046687522
- Cited by
- 586
- References
- 22
- FWCI
- 3.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer. https://app.cochat.ai/papers/10.1016/s0360-3016(01)01630-3
- The paper
- Brizel, D. M., Schroeder, T., Scher, R. L., Walenta, S., Clough, R. W., Dewhirst, M. W., & Mueller-Klieser, W. (2001). Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer. International Journal of Radiation Oncology*Biology*Physics. https://doi.org/10.1016/s0360-3016(01)01630-3
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
