The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Role of oxidative stress and mitochondrial changes in cyanobacteria-induced apoptosis and hepatotoxicity
Abstract
Microcystins produced by cyanobacteria are potent and specific hepatotoxins; however, the mechanisms of microcystin-induced hepatotoxicity have not been fully elucidated. The induction of free radical formation and mitochondrial alterations are two major events found in microcystin-treated cultured rat hepatocytes. The mitochondrial alterations, i.e. loss of mitochondrial membrane potential and mitochondria permeability transition are now recognized as key steps in apoptosis. The activation of calpain and Ca(2+)/calmodulin-dependent protein kinase II is believed to be critical in the microcystin-induced apoptotic process.
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Liver Failure and Death after Exposure to Microcystins at a Hemodialysis Center in Brazil
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Inhibition of protein phosphatases by microcystis and nodularin associated with hepatotoxicity
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Cited by
Genotoxicity and potential carcinogenicity of cyanobacterial toxins – a review
Žegura, B., Štraser, A., & Filipič, M. (2011) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2011.01.002 · Cited by 324
Toxins produced in cyanobacterial water blooms - toxicity and risks
Bláha, L., Babica, P., & Maršálek, B. (2009) · Interdisciplinary Toxicology · doi:10.2478/v10102-009-0006-2 · Cited by 316
Oxidative stress generation by microcystins in aquatic animals: Why and how
Amado, L. L., & Monserrat, J. M. (2010) · Environment International · doi:10.1016/j.envint.2009.10.010 · Cited by 314
Toxicity of statins on rat skeletal muscle mitochondria
Kaufmann, P., Török, M., Zahno, A., Waldhauser, K. M., Brecht, K., & Krähenbühl, S. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-006-6235-z · Cited by 263
Metadata
- Authors
- Ding, W.-X., & Nam Ong, C.
- Venue
- FEMS Microbiology Letters
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-03
- Volume
- 220
- Issue
- 1
- Pages
- 1-7
- ISSN
- 0378-1097 (ISSN-L)
- 1574-6968
- OpenAlex
- W2112683748
- Cited by
- 263
- References
- 30
- FWCI
- 11.85
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ding, W.-X., & Nam Ong, C. (2003). Role of oxidative stress and mitochondrial changes in cyanobacteria-induced apoptosis and hepatotoxicity. FEMS Microbiology Letters. https://doi.org/10.1016/s0378-1097(03)00100-9
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
