The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Mitochondria and Apoptosis
Abstract
REVIEW A variety of key events in apoptosis focus on mitochondria, including the release of caspase activators (such as cytochrome c), changes in electron transport, loss of mitochondrial transmembrane potential, altered cellular oxidation-reduction, and participation of pro- and antiapoptotic Bcl-2 family proteins. The different signals that converge on mitochondria to trigger or inhibit these events and their downstream effects delineate several major pathways in physiological cell death.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Toward the molecular structure of the mitochondrial channel, VDAC
Mannella, C. A., Forte, M., & Colombini, M. (1992) · Journal of Bioenergetics and Biomembranes · doi:10.1007/bf00769525 · Cited by 150
Research works printed but not linked: 51
- Margulis L., Proc. Natl. Acad. Sci. U.S.A. 93, 1071 (1996). · DOI · Paper page
- Blackstone N. W., Evolution 49, 785 (1995).
- Frade J. M., Michaelidis T. M., Bioessays 19, 827 (1997). · DOI
- Kroemer G., Cell Death Differ. 4, 443 (1997). · DOI
- Jacobson M. D., et al., Nature 361, 365 (1993). · DOI · Paper page
- McCarthy N. J., Whyte M. K. B., Gilbert C. S., Evan G. I., J. Cell Biol. 136, 215 (1997). · DOI · Paper page
- Brunet C. L., et al., Cell Death Differ. 5, 107 (1998). · DOI
- Hirsch T., et al., Oncogene 15, 1573 (1997). · DOI · Paper page
- Xiang J., Chao D. T., Korsmeyer S. J., Proc. Natl. Acad. Sci. U.S.A. 93, 14559 (1996). · DOI · Paper page
- Scaife J. F., Can. J. Biochem. 44, 433 (1966). · DOI
- Garcı́a-Ruiz C., Colell A., Marı́ M., Morales A., Fernández-Checa J. C., J. Biol. Chem. 272, 11369 (1997). · DOI · Paper page
- Bossy-Wetzel E., Newmeyer D. D., Green D. R., EMBO J. 17, 37 (1998). · DOI · Paper page
- Eguchi Y., Shimizu S., Tsujimoto Y., Cancer Res. 57, 1835 (1997).
- 10.1016/0092-8674(94)90203-8 · DOI · Paper page
- Liu X., Kim C. N., Yang J., Jemmerson R., Wang X., ibid. 86, 147 (1996).
- 10.1126/science.275.5303.1129 · DOI · Paper page
- 10.1016/S0092-8674(00)80434-1 · DOI · Paper page
- Jurgensmeier J. M., et al., Proc. Natl. Acad. Sci. U.S.A. 95, 4997 (1998). · DOI · Paper page
- Kuwana T., et al., J. Biol. Chem. 273, 16589 (1998). · DOI · Paper page
- Mancini M., et al., J. Cell Biol. 140, 1485 (1998). · DOI · Paper page
- 10.1038/384368a0 · DOI · Paper page
- Susin S. A., et al., J. Exp. Med. 184, 1331 (1996). · DOI · Paper page
- Susin S., et al., ibid. 186, 25 (1997).
- Bredesen D. E., Ann. Neurol. 38, 839 (1995). · DOI · Paper page
- Jacobson M. D., Raff M. C., Nature 374, 814 (1995). · DOI · Paper page
- Degli Esposti M., McLennan H., FEBS Lett. 430, 338 (1998). · DOI
- Petit P. X., Susin S.-A., Zamzami N., Mignotte B., Kroemer G., ibid. 396, 7 (1996).
- Qian T., Herman B., Lemasters J., Cell Vision 4, 166 (1997).
- Bernardi P., Broekemeier K. M., Pfeiffer D. R., J. Bioenerg. Biomembr. 26, 509 (1994). · DOI · Paper page
- Zamzami N., et al., FEBS Lett. 384, 53 (1996). · DOI · Paper page
- Zamzami N., et al., J. Exp. Med. 183, 1533 (1996). · DOI · Paper page
- Xiang J., Chao D. T., Korsmeyer S. J., Proc. Natl. Acad. Sci. U.S.A. 93, 14559 (1996). · DOI · Paper page
- Marzo I., et al., J. Exp. Med. 187, 1261 (1998). · DOI · Paper page
- Ichas F., Jouaville L. S., Mazat J.-P., Cell 89, 1145 (1997). · DOI · Paper page
- Metivier D., et al., Immunol. Lett. 61, 157 (1998). · DOI
- Wyllie A. H., Kerr J. F. R., Currie A. R., Int. Rev. Cytol. 68, 251 (1980). · DOI · Paper page
- Krajewski S., et al., Cancer Res. 53, 4701 (1993).
- 10.1016/0092-8674(94)90506-1 · DOI · Paper page
- Marchetti P., et al., J. Exp. Med. 184, 1155 (1996). · DOI · Paper page
- Shimizu S., et al., Oncogene 13, 21 (1996).
- 10.1126/science.8235659 · DOI
- Shimizu S., et al., Cancer Res. 56, 2161 (1996).
- Hurt K. J., et al., J. Neurochem. 65, 2432 (1995). · DOI
- Baffy G., Miyashita T., Williamson J. R., Reed J. C., J. Biol. Chem. 268, 6511 (1993). · DOI · Paper page
- Shimizu S., et al., Proc. Natl. Acad. Sci. U.S.A. 95, 1455 (1998). · DOI · Paper page
- Muchmore S. W., et al., Nature 381, 335 (1996). · DOI · Paper page
- Schendel S. L., et al., Proc. Natl. Acad. Sci. U.S.A. 94, 5113 (1997). · DOI · Paper page
- Minn A. J., et al., Nature 385, 353 (1997). · DOI · Paper page
- Antonsson B., et al., Science 277, 370 (1997). · DOI · Paper page
- Schlesinger P., et al., Proc. Natl. Acad. Sci. U.S.A. 94, 11357 (1997). · DOI · Paper page
- Matsuyama S., Xu Q., Velours J., Reed J. C., Mol. Cell 1, 327 (1998). · DOI · Paper page
Cited by
Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219
Hengartner, M. O. (2000) · Nature · doi:10.1038/35037710 · Cited by 5,779
Cellular survival: a play in three Akts
Datta, S. R., Brunet, A., & Greenberg, M. E. (1999) · Genes & Development · doi:10.1101/gad.13.22.2905 · Cited by 4,216
Molecular characterization of mitochondrial apoptosis-inducing factor
Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., Brothers, G. M., Mangion, J., Jacotot, E., Costantini, P., Loeffler, M., et al. (1999) · Nature · doi:10.1038/17135 · Cited by 4,060
The Bcl2 family: regulators of the cellular life-or-death switch
Cory, S., & Adams, J. M. (2002) · Nature Reviews Cancer · doi:10.1038/nrc883 · Cited by 4,032
Metadata
- Authors
- Green, D. R., & Reed, J. C.
- Venue
- Science
- Published
- 1998-08-28
- Volume
- 281
- Issue
- 5381
- Pages
- 1309-1312
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2113999599
- Cited by
- 8,965
- References
- 1
- FWCI
- 177.27
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Mitochondria and Apoptosis. https://app.cochat.ai/papers/10.1126/science.281.5381.1309
- The paper
- Green, D. R., & Reed, J. C. (1998). Mitochondria and Apoptosis. Science. https://doi.org/10.1126/science.281.5381.1309
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.