The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Long-Term Effect of Right Ventricular Pacing on Myocardial Perfusion and Function
Open accessAbstract
OBJECTIVES The purpose of this study was to investigate the effect of long-term ventricular pacing on myocardial perfusion and function in patients receiving such pacing. BACKGROUND The long-term effect of ventricular pacing on myocardial perfusion and function in humans is unclear, although animal studies have suggested that it may be adverse. METHODS Forty-three patients with complete heart block and dual-chamber rate-adaptive (DDDR) pacing were studied. All underwent thallium-201 (Tl-201) exercise myocardial scintigraphy to assess myocardial perfusion and radionuclide ventriculography to determine left ventricular function and regional wall motion. Coronary angiography was also performed in patients with abnormal findings on Tl-201 study. RESULTS There was no significant difference in mean age, gender, percent ventricular pacing, pacing threshold, ventricular pacing output and metabolic equivalents on exercise testing between patients with or without perfusion defects on exercise Tl-201 scintigraphy. However, the duration of pacing tended to be longer in patients with than in those without perfusion defects (43.9 +/- 49.7 vs. 20.1 +/- 9.8 months, p = 0.05). Tl-201 perfusion defects were noted in 28 (65%) of 43 of patients (inferior 78% [n = 22], apical 67% [n = 17], septal 21% [n = 6], anterior 7% [n = 2], lateral 3% [n = 1)]. Of 16 of 28 patients with abnormal Tl-201 findings who underwent coronary angiography, only 3 (19%) had significant coronary artery disease. Patients with an abnormal perfusion defect had a significantly lower left ventricular ejection fraction (48.5 +/- 9.9% vs. 59.6 +/- 8.9%, p < 0.001) and a higher percent of wall motion abnormalities (57% vs. 20%, p = 0.026), mainly over apical regions. CONCLUSIONS Long-term right ventricular apical pacing resulted in a high incidence of myocardial perfusion defects that increased with the duration of pacing. These myocardial perfusion abnormalities were associated with apical wall motion abnormalities and impaired global left ventricular function.
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Redistribution of myocardial fiber strain and blood flow by asynchronous activation
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A modified method for the in vivo labeling of red blood cells with Tc-99m: concise communication.
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Thallium-201 scintigraphy in complete left bundle branch block
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Right ventricular pacing reduces the rate of left ventricular relaxation and filling
Zile, M. R., Blaustein, A. S., Shimizu, G., & Gaasch, W. H. (1987) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(87)80215-2 · Cited by 191
Influence of pacing site on canine left ventricular contraction
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Deshmukh, P., Casavant, D. A., Romanyshyn, M., & Anderson, K. (2000) · Circulation · doi:10.1161/01.cir.101.8.869 · Cited by 770
Clinical Outcomes of His Bundle Pacing Compared to Right Ventricular Pacing
Abdelrahman, M., Subzposh, F. A., Beer, D., Durr, B., Naperkowski, A., Sun, H., Oren, J. W., Dandamudi, G., & Vijayaraman, P. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.02.048 · Cited by 589
Sharma, P. S., Dandamudi, G., Naperkowski, A., Oren, J. W., Storm, R. H., Ellenbogen, K. A., & Vijayaraman, P. (2015) · Heart Rhythm · doi:10.1016/j.hrthm.2014.10.021 · Cited by 388
Functional abnormalities in patients with permanent right ventricular pacing
Tse, H.-F., Yu, C., Wong, K.-K., Tsang, V., Leung, Y.-L., Ho, W.-Y., & Lau, C.-P. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02169-1 · Cited by 354
Self-citationZHANG, X., CHEN, H., SIU, C., YIU, K., CHAN, W., LEE, K. L., CHAN, H., LEE, S. W., FU, G., LAU, C., et al. (2008) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2007.01014.x · Cited by 260
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Metadata
- Authors
- Tse, H.-F., & Lau, C.-P.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 1997-03
- Volume
- 29
- Issue
- 4
- Pages
- 744-749
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W1991501639
- Cited by
- 462
- References
- 23
- FWCI
- 5.81
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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