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Cited by 123Medication Adherence and ComplianceHIV/AIDS Research and InterventionsPharmacy and Medical Practices

A medication self-management program to improve adherence to HIV therapy regimens

Smith, Scott R, Rublein, John C, Marcus, Cheryl, Brock, Tina Penick, Chesney, Margaret A·2003·Patient Education and Counseling
DOI 10.1016/s0738-3991(02)00127-1
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Abstract

This study examined whether a self-management intervention based on feedback of adherence performance and principles of social cognitive theory improves adherence to antiretroviral dosing schedules. Forty-three individuals with HIV/AIDS who were starting or switching to a new protease inhibitor regimen were randomly assigned to be in a medication self-management program or usual care control group. The self-management program included skills development exercises, three monthly visits for medication consultations, and monthly feedback of adherence performance using electronic monitors on medication bottles. Participants also completed a 40-item questionnaire that measured self-efficacy to take medications, on schedule, in a variety of situations. Logistic regression analysis indicated that individuals in the self-management group were significantly more likely to take 80% or more of their doses each week than individuals in the control group (n=29, OR=7.8, 95% CI=2.2-28.1). Self-management training with feedback of adherence performance is a potentially useful model for improving adherence to complex regimens in HIV/AIDS care.

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Crossref · 10.1016/s0738-3991(02)00127-1

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  • Confidence in one's ability to pursue goals affects how well people adhere to medication across many long-term illnesses.

    “Self-efficacy or confidence in one’s ability to successfully engage in goal-directed behavior has been shown to influence medication adherence across many chronic illnesses.”

    From Reliability and validity of a self‐efficacy instrument for hepatitis C antiviral treatment regimens (2012) · cites this paper as [19]

  • The VIRAHEP-C self-efficacy measure was a 24-item self-report adapted from validated self-efficacy measures used in the Adult AIDS Clinical Trials Group.

    “The VIRAHEP-C self-efficacy measure was a 24-item self-report measure adapted from previously validated self-efficacy measures created for the Adult AIDS Clinical Trials Group (see Appendix A for the original VIRAHEP-C measure) (19;39) (personal communication, S. Smith, Nov. 11, 2010).”

    From Reliability and validity of a self‐efficacy instrument for hepatitis C antiviral treatment regimens (2012) · cites this paper as [19]

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Authors
Smith, S. R., Rublein, J. C., Marcus, C., Brock, T. P., & Chesney, M. A.
Affiliations
  • University of North Carolina at Chapel Hill (US)
  • University of California, San Francisco (US)
Corresponding author
Smith, Scott R
ORCID
Venue
Patient Education and Counseling
Publisher
Elsevier BV
Published
2003-06
Volume
50
Issue
2
Pages
187-199
ISSN
0738-3991 (ISSN-L)
DOI
10.1016/s0738-3991(02)00127-1
OpenAlex
W2014019173
Cited by
123
References
34
Citations by year
2024: 3 · 2022: 3 · 2021: 2 · 2020: 3 · 2019: 4 · 2018: 1 · 2017: 7 · 2016: 9 · 2015: 2 · 2014: 7 · 2013: 13 · 2012: 9
FWCI
5.69
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Patient Education and Counseling (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Center for Research Resources (RR00046, M01RR000046)
Topics
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
Keywords
medication adherence, HIV/AIDS, antiretroviral therapy, protease inhibitors, medication self-management, social cognitive theory, self-efficacy, electronic medication monitors, pharmaceutical consultation, complex medication regimens
MeSH terms
Adult, Drug Administration Schedule, Female, Humans, Health Knowledge, Attitudes, Practice, Male, Middle Aged, North Carolina, Patient Compliance, Patient Education as Topic, Surveys and Questionnaires, Self Administration, Program Evaluation, HIV Infections, Logistic Models, Models, Educational, HIV Protease Inhibitors, Anti-HIV Agents, Self Efficacy, Feedback, Psychological

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