The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Effects of smoking during pregnancy
Abstract
BACKGROUND The purpose of this study was to estimate, using meta-analysis, pooled odds ratios for the effects of smoking on five pregnancy complications: placenta previa, abruptio placenta, ectopic pregnancy, preterm premature rupture of the membrane (PPROM), and pre-eclampsia. METHODS Published articles were identified through computer search and literature review. Five criteria were applied to those studies initially identified to determine those eligible for the meta-analysis. A random effects model was applied to derive pooled odds ratios for the eligible studies for each pregnancy complication. Meta-analyses were repeated on subsets of the studies to confirm the overall results. RESULTS Smoking was found to be strongly associated with an elevated risk or placenta previa, abruptio placenta, ectopic pregnancy, and PPROM, and a decreased risk of pre-eclampsia. All pooled odds ratios were statistically significant. The pooled ratios ranged from 1.58 for placenta previa to 1.77 for ectopic pregnancy. The pooled odds ratio for pre-eclampsia was 0.51 and all subset analyses confirmed this seemingly protective effect. CONCLUSIONS Smoking during pregnancy is a significant and preventable factor affecting ectopic pregnancy, placental abruption, placenta previa, and PPROM. The findings of smoking's apparently protective effect on pre-eclampsia should be balanced with these harmful effects. In addition, the biological linkage between smoking and pre-eclampsia is not yet well understood. Pregnant women should be advised to stop smoking in order to reduce the overall risk of pregnancy complications as well as any risk of adverse impact on the unborn child.
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Cites
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Effect of Maternal Cigarette Smoking on Pregnancy Complications and Sudden Infant Death Syndrome
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Risk factors for preterm premature rupture of fetal membranes: A multicenter case-control study
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Cited by
Bellamy, L., Casas, J.-P., Hingorani, A. D., & Williams, D. J. (2007) · BMJ · doi:10.1136/bmj.39335.385301.be · Cited by 2,552
Mercer, B. M., Goldenberg, R. L., Meis, P. J., Moawad, A. H., Shellhaas, C., Das, A., Menard, M. K., Caritis, S. N., Thurnau, G. R., Dombrowski, M. P., et al. (2000) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2000.106766 · Cited by 360
Epidemiology of prenatal smoking and perinatal outcomes
Salihu, H. M., & Wilson, R. E. (2007) · Early Human Development · doi:10.1016/j.earlhumdev.2007.08.002 · Cited by 343
McCowan, L. M. E., Dekker, G. A., Chan, E., Stewart, A., Chappell, L. C., Hunter, M., Moss-Morris, R., North, R. A., & On behalf of the SCOPE consortium (2009) · BMJ · doi:10.1136/bmj.b1081 · Cited by 284
“A causal and dose dependent relationship has been established between smoking during pregnancy and the risk of having a small for gestational age infant and of spontaneous preterm birth.”
BackgroundACOG Committee Opinion No. 762: Prepregnancy counseling
(2019) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000003013 · Cited by 272
Metadata
- Authors
- Castles, A., Adams, E. K., Melvin, C. L., Kelsch, C., & Boulton, M. L.
- Venue
- American Journal of Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 1999-04
- Volume
- 16
- Issue
- 3
- Pages
- 208-215
- ISSN
- 0749-3797 (ISSN-L)
- OpenAlex
- W1975018846
- Cited by
- 425
- References
- 48
- FWCI
- 10.43
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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