The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Temporal Prediction Errors in a Passive Learning Task Activate Human Striatum
Open accessAbstract
Functional MRI experiments in human subjects strongly suggest that the striatum participates in processing information about the predictability of rewarding stimuli. However, stimuli can be unpredictable in character (what stimulus arrives next), unpredictable in time (when the stimulus arrives), and unpredictable in amount (how much arrives). These variables have not been dissociated in previous imaging work in humans, thus conflating possible interpretations of the kinds of expectation errors driving the measured brain responses. Using a passive conditioning task and fMRI in human subjects, we show that positive and negative prediction errors in reward delivery time correlate with BOLD changes in human striatum, with the strongest activation lateralized to the left putamen. For the negative prediction error, the brain response was elicited by expectations only and not by stimuli presented directly; that is, we measured the brain response to nothing delivered (juice expected but not delivered) contrasted with nothing delivered (nothing expected).
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In the citing paper
“Research suggests that to make this choice, the brain uses representations of reward-expectancy and effort/risk requirement from prior experiences to optimize cost/benefit”
From Food reward, hyperphagia, and obesity (2011) · cites this paper as [111]
In the citing paper
“This is consistent with many previous accounts (McClure et al., 2003; O’Doherty et al., 2003; Seymour et al., 2004).”
From States versus Rewards: Dissociable Neural Prediction Error Signals Underlying Model-Based and Model-Free Reinforcement Learning (2010) · cites this paper as McClure et al., 2003
In the citing paper
“These changes in striatum BOLD activity coincide with the process of learning how to predict rewards 15, 16 – an observation supported by electrophysiological properties of its dopaminergic afferents.”
From The social brain and reward: Social information processing in the human striatum (2014) · cites this paper as [16]
In the citing paper
“and that this region may not be selective for the learning and prediction of rewarding outcomes (McClure et al., 2003; O’Doherty et al., 2004; 2003).”
From Neural correlates of social exclusion across ages: A coordinate-based meta-analysis of functional MRI studies (2017) · cites this paper as McClure et al., 2003
Citations
Cites
AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages
Cox, R. W. (1996) · Computers and Biomedical Research · doi:10.1006/cbmr.1996.0014 · Cited by 10,913
Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688
A neural substrate of prediction and reward
Schultz, W., Dayan, P., & Montague, P. R. (1997) · Science · doi:10.1126/science.275.5306.1593 · Cited by 9,388
Self-citationPredictive reward signal of dopamine neurons
Schultz, W. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.1.1 · Cited by 4,564
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127
Analysis of fMRI Time-Series Revisited
Friston, K. J., Holmes, A. P., Poline, J., Grasby, P. M., Williams, S., Frackowiak, R. S. J., & Turner, R. (1995) · NeuroImage · doi:10.1006/nimg.1995.1007 · Cited by 2,504
Anticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens
Knutson, B., Adams, C. M., Fong, G. W., & Hommer, D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-16-j0002.2001 · Cited by 2,244
A framework for mesencephalic dopamine systems based on predictive Hebbian learning
Montague, P., Dayan, P., & Sejnowski, T. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-05-01936.1996 · Cited by 2,066
Self-citationAbstract reward and punishment representations in the human orbitofrontal cortex
O'Doherty, J., Kringelbach, M. L., Rolls, E. T., Hornak, J., & Andrews, C. (2001) · Nature Neuroscience · doi:10.1038/82959 · Cited by 2,003
Wise, R. A., & Rompre, P.-P. (1989) · Annual Review of Psychology · doi:10.1146/annurev.ps.40.020189.001203 · Cited by 1,968
Cited by
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The reward circuit: linking primate anatomy and human imaging
Haber, S. N., & Knutson, B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.129 · Cited by 3,718
Separate neural systems value immediate and delayed monetary rewards
McClure, S. M., Laibson, D. I., Loewenstein, G., & Cohen, J. D. (2004) · Science · doi:10.1126/science.1100907 · Cited by 3,089
Self-citationCortical substrates for exploratory decisions in humans
Daw, N. D., O'Doherty, J. P., Dayan, P., Seymour, B., & Dolan, R. J. (2006) · Nature · doi:10.1038/nature04766 · Cited by 2,224
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning
O'Doherty, J., Dayan, P., Schultz, J., Deichmann, R., Friston, K., & Dolan, R. J. (2004) · Science · doi:10.1126/science.1094285 · Cited by 2,088
Balleine, B. W., & O'Doherty, J. P. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.131 · Cited by 1,775
Metadata
- Authors
- McClure, S. M., Berns, G. S., & Montague, P. R.
- Affiliations
- Baylor College of Medicine (US)
- Emory University (US)
- Corresponding author
- Montague, P.Read
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2003-04
- Volume
- 38
- Issue
- 2
- Pages
- 339-346
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2157088567
- Cited by
- 917
- References
- 32
- Citations by year
- 2026: 11 · 2025: 15 · 2024: 18 · 2023: 23 · 2022: 23 · 2021: 32 · 2020: 18 · 2019: 28 · 2018: 31 · 2017: 36 · 2016: 47 · 2015: 39 · 2014: 50 · 2013: 52 · 2012: 77
- FWCI
- 16.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- National Institutes of Health (5r01mh061010-02)
- National Institute of Mental Health (R01 MH61010, R01MH52797, R01MH052797)
- National Institute on Drug Abuse (K08 DA00367, K08DA000367, R01-DA11723, R01DA011723)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- prediction error, striatum, putamen, reward anticipation, temporal prediction, expectation errors, BOLD signal
- MeSH terms
- Adult, Conditioning, Classical, Corpus Striatum, Cues, Female, Humans, Learning, Magnetic Resonance Imaging, Male, Nucleus Accumbens, Photic Stimulation, Reaction Time, Reference Values, Regression Analysis, Taste, Time Factors, Time Perception
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