The DOI matches its Crossref record; 75 of the 81 references it cites were found in a registry or an index.
Historical aspects of the dichotomy between manic-depressive disorders and schizophrenia
Abstract
The history of psychiatric classification is highly complex and this presentation must be restricted to a simplified overview. Guislain [Guislain, J., 1833. Traité des phrénopathies ou doctrine nouvelle des maladies mentales. Etablissement Encyclopédique, Brussels] and Zeller [Beil. Med. Corresp.-Bl. Würtemb. Arztl. Ver. 7 (1837) 321] established a unitarian concept of psychiatric disorder, permutations of which have survived until the present day. Kraepelin's [Kraepelin, E., 1899. Psychiatrie. Ein Lehrbuch für Studierende und Arzte (6th edn.). Johann Ambrosius Barth, Leipzig] dichotomy between "manic-depressive insanity" and dementia praecox was built mainly on Kahlbaum's [Kahlbaum, K., 1863. Die Gruppirung der Psychischen Krankheiten und die Eintheilung der Seelenstörungen. AW Kafemann, Danzig] classification, which took clinical symptoms, course and outcome into account. Kraepelin's well-accepted approach sought to provide a basis for diagnosis, prognosis, choice of treatment and causal research. Kraepelin's dichotomy came to be questioned on several grounds: (1) doubts about his unification of bipolar disorder [Gaz. Hôp. 24 (1851) 18] with melancholia, (2) doubts about the significance of Kraepelin's diagnostic groups for causal research [Z. Gesamte Neurol. Psychiatr. 12 (1912) 540], illustrated best by the work of Bonhoeffer [Bonhoefferm, K., 1912. Die symptomatischen Psychosen im Gefolge akuter Infektionen, Allgemeinerkrankungen und innerer Krankheiten. In: Aschaffenburg, G. (Ed.), Handbuch der Psychiatrie, 3. Abt., 1. Hälfte. Deuticke, Leipzig Wien], (3) the complex psychopathological descriptions and classifications of numerous subgroups of psychoses by Kleist [Monatsschr. Psychiatr. Neurol. 125 (1953) 526] and Leonhard [Leonhard, K., 1968. Aufteilung der endogenen Psychosen (4th edn.). Akademie Verlag, Berlin] and (4) description of the psychoses between affective and schizophrenic disorders (intermediate psychoses, mixed psychoses, schizo-affective psychoses) beginning with Kehrer and Kretschmer [Kehrer, F., Kretschmer, E., 1924. Die Veranlagung zu seelischen Störungen. (Monographien aus dem Gesamtgebiete der Neurologie 40) Springer, Berlin] and persisting up to the modern findings of a continuum between the two major groups of psychiatric disorders. Kraepelin's simplification has so far been more successful than the Kleist-Leonhard approach, but the modern and more descriptive trend in psychiatric classification favours the syndromal concept of Hoche and the concepts of continua between affective and schizophrenic disorders and between normal and pathological behaviour.
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“Kraepelin's dichotomization proved later not to be entirely true because some patients with schizophrenia recovered completely”
From Excess early mortality in schizophrenia. (2014) · cites this paper as Angst 2002
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“Thus, this key feature of the dichotomization still applies for today’s patients.”
From Life expectancy and death by diseases of the circulatory system in patients with bipolar disorder or schizophrenia in the Nordic countries. (2013) · cites this paper as [30]
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Cites
Negative v Positive Schizophrenia
Andreasen, N. C. (1982) · Archives of General Psychiatry · doi:10.1001/archpsyc.1982.04290070025006 · Cited by 2,008
A Family Study of Schizoaffective, Bipolar I, Bipolar II, Unipolar, and Normal Control Probands
Gershon, E. S. (1982) · Archives of General Psychiatry · doi:10.1001/archpsyc.1982.04290100031006 · Cited by 987
(1970) · Annals of Internal Medicine · doi:10.7326/0003-4819-72-6-971_2 · Cited by 708
Psychiatrie: Ein Lehrbuch für Studierende und Ärzte
Kraepelin, E. (1939) · JAMA · doi:10.1001/jama.1939.02800520075036 · Cited by 686
The Early Symptoms of Schizophrenia
Chapman, J. (1966) · British Journal of Psychiatry · doi:10.1192/bjp.112.484.225 · Cited by 675
THE ACUTE SCHIZOAFFECTIVE PSYCHOSES
KASANIN, J. (1933) · American Journal of Psychiatry · doi:10.1176/ajp.90.1.97 · Cited by 524
Aufteilung der endogenen Psychosen
Leonhard, K. (1957) · De Gruyter eBooks · doi:10.1515/9783112765913 · Cited by 500
Zur Ätiologie und Nosologie endogener depressiver psychosen
Angst, J. (1966) · Monographien aus dem Gesamtgebiete der Neurologie und Psychiatrie · doi:10.1007/978-3-642-88741-3 · Cited by 385
Self-citationContinuity and Discontinuity of Affective Disorders and Schizophrenia
Maier, W. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820230041004 · Cited by 384
Die erscheinungsformen des Irreseins
Kraepelin, E. (1920) · Zeitschrift für die gesamte Neurologie und Psychiatrie · doi:10.1007/bf02887354 · Cited by 344
Research works printed but not linked: 14
- Bumke, 1909, Über die Umgrenzung manisch-depressiven Irreseins, Zentralbl. Nervenheilkd. Psychiatr, N.F., 20, 381
- Falret, 1851, Marche de la folie, Gaz. Hôp., 24, 18
- Flemming, 1844, Über Classification der Seelenstörungen nebst einem neuen Versuche derselben mit besonderer Rücksicht auf gerichtliche Psychologie, Allg. Z. Psychiatr., 1, 97
- Haustgen, 1993, Jean-Pierre Falret ou les débuts de la clinique psychiatrique moderne, Synapse, 95
- Heimann, 1986, Spezifität und Unspezifität bei psychischen Erkrankungen, Schweiz. Arch. Neurol. Neurochir. Psychiatr., 137, 67
- Huber, 1966, Reine Defektsyndrome und Basisstadien endogener Psychosen, Fortschr. Neurol. Psychiatr., 34, 409
- Kahlbaum, 1882, Über cyklisches Irresein, Irrenfreund, 24, 145
- Kick, 1981, Die Dichotomie der idiopathischen Psychosen im Syndromprofil-vergleich der Kraepelinschen Krankheitsbeschreibungen, Nervenarzt, 52, 522
- Kraepelin, 1897, Ziele und Wege der klinischen Psychiatrie (3. Sitzung, 19.9.1996), Allg. Z. Psychiatr., 53, 840
- Perris, 1966, A study of bipolar (manic–depressive) and unipolar recurrent depressive psychoses, Acta Psychiatr. Scand.,, 194, 1
- Rennert, 1965, Die Universalgenese der endogenen Psychosen. Ein Beitrag zum Problem “Einheitspsychose”, Fortschr. Neurol. Psychiatr., 33, 251
- Smith, 1925, Atypical psychoses and heterologous hereditary taints, J. Nerv. Ment. Dis., 62, 1
- Zeller, 1837, Bericht über die Wirksamkeit der Heilanstalt Winnenthal von ihrer Eröffnung den 1. März 1834 bis zum 28. February 1837, Beil. Med. Corresp.-Bl. Würtemb. Ärztl. Ver., 7, 321
- Zendig, 1909, Beiträge zur Differentialdiagnose des manisch-depressiven Irreseins und der Dementia praecox, Allg. Z. Psychiatr., 66, 932
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Morra, D., Ficca, G., & Barbato, G. (2026) · ALPHA PSYCHIATRY · doi:10.31083/ap52900
Ruby, E., Gonen, O., Lotan, E., Tal, A., Rusinek, H., Clemente, J. C., Robinson‐Papp, J., Karlsgodt, K. H., & Malaspina, D. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.04.27.721016
Metadata
- Authors
- Angst, J.
- Affiliations
- University of Zurich (CH)
- Corresponding author
- Angst, Jules
- ORCID
- Angst, Jules
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2002-09
- Volume
- 57
- Issue
- 1
- Pages
- 5-13
- ISSN
- 0920-9964 (ISSN-L)
- OpenAlex
- W2090250370
- Cited by
- 127
- References
- 81
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 6 · 2022: 2 · 2021: 10 · 2020: 17 · 2019: 3 · 2018: 2 · 2017: 7 · 2016: 8 · 2015: 2 · 2014: 4 · 2013: 4 · 2012: 10
- FWCI
- 7.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Historical Psychiatry and Medical Practices
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Keywords
- manic-depressive insanity
- MeSH terms
- Bipolar Disorder, Diagnosis, Differential, Humans, Psychotic Disorders, Schizophrenia, History, 19th Century, History, 20th Century
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