The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Structural and functional analysis of the BMP-4 promoter in early embryos of xenopus laevis.
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Dilution will diminish expression of age-elevated autoinducers and feedback will decrease their levels for a prolonged time.
“where dilution will diminish their expression and feedback will decrease the levels for a prolonged time [48–56].”
From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [53]
Section 2.4 reports a positive BMP-4 auto-regulatory loop and reduced promoter activity when BMP signaling is blocked, supporting the feedback component. The paper studies early Xenopus embryos; it does not show that dilution reduces expression of age-elevated autoinducers or that their levels remain low for a prolonged time. (LLM, conf=0.83)
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Francois, V, Solloway, M., O'Neill, J. W., Emery, J., & Bier, E. (1994) · Genes & Development · doi:10.1101/gad.8.21.2602 · Cited by 308
Conversion of Dorsal from an activator to a repressor by the global corepressor Groucho
Dubnicoff, T., Valentine, S. A., Chen, G., Shi, T., Lengyel, J. A., Paroush, Z., & Courey, A. J. (1997) · Genes & Development · doi:10.1101/gad.11.22.2952 · Cited by 155
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Research works printed but not linked: 46
- Bearer, 1994, Distribution of Xrel in the early Xenopus embryo: a cytoplasmic and nuclear gradient, Eur. J. Cell Biol., 63, 255
- Dale, 1992, Bone morphogenetic protein 4: a ventralizing factor in Xenopus development, Development, 115, 573, 10.1242/dev.115.2.573 · DOI
- De Robertis, 1996, A common plan for dorsoventral patterning in Bilateria, Nature, 380, 37, 10.1038/380037a0 · DOI · Paper page
- Dosch, 1997, Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus, Development, 124, 2325, 10.1242/dev.124.12.2325 · DOI
- Fainsod, 1994, On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo, EMBO J., 13, 5015, 10.1002/j.1460-2075.1994.tb06830.x · DOI
- Fainsod, 1997, The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4, Mech. Dev., 63, 39, 10.1016/S0925-4773(97)00673-4 · DOI
- Feng, 1995, The mouse bone morphogenetic protein-4 gene, J. Biol. Chem., 270, 28364, 10.1074/jbc.270.47.28364 · DOI
- Ferguson, 1992, Localized enhancement and repression of the activity of the TGF-β family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo, Development, 114, 583, 10.1242/dev.114.3.583 · DOI
- Graff, 1994, Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo, Cell, 79, 169, 10.1016/0092-8674(94)90409-X · DOI
- Graff, 1997, Embryonic patterning: to BMP or not to BMP, that is the question, Cell, 89, 171, 10.1016/S0092-8674(00)80196-8 · DOI
- Hammerschmidt, 1996, Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor, Genes Dev., 10, 2452, 10.1101/gad.10.19.2452 · DOI
- Hemmati-Brivanlou, 1995, Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4, Dev. Genet., 17, 78, 10.1002/dvg.1020170109 · DOI
- Hogan, 1996, Bone morphogenetic proteins: multifunctional regulators of vertebrate development, Genes Dev., 10, 1580, 10.1101/gad.10.13.1580 · DOI
- Holley, 1995, A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin, Nature, 376, 249, 10.1038/376249a0 · DOI
- Huang, 1993, The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression, Genes Dev., 7, 694, 10.1101/gad.7.4.694 · DOI · Paper page
- Huang, 1995, Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic, Genes Dev., 9, 3177, 10.1101/gad.9.24.3177 · DOI
- Irish, 1987, The decapentaplegic gene is required for dorsal-ventral patterning in the Drosophila embryo, Genes Dev., 1, 868, 10.1101/gad.1.8.868 · DOI
- Jackson, 1994, Embryonic expression patterns of the Drosophila decapentaplegic gene: separate regulatory elements control blastoderm expression and lateral ectodermal expression, Dev. Dyn., 199, 28, 10.1002/aja.1001990104 · DOI
- Jefferies, 1995, Dorsoventral axis inversion?, Nature, 374, 22, 10.1038/374022a0 · DOI
- Jiang, 1993, Conversion of a dorsal-dependent silencer into an enhancer: evidence for dorsal co-repressors, EMBO J., 12, 3201, 10.1002/j.1460-2075.1993.tb05989.x · DOI · Paper page
- Jones, 1992, DVR-4 (bone morphogenetic protein-4) as a postero-ventralizing factor in Xenopus mesoderm induction, Development, 115, 639, 10.1242/dev.115.2.639 · DOI
- Kao, 1991, Expression of a mRNA related to c-rel and dorsal in early Xenopus leavis embryos, Proc. Natl. Acad. Sci USA, 88, 2697, 10.1073/pnas.88.7.2697 · DOI
- Kirov, 1993, Conversion of a silencer into an enhancer: evidence for a co-repressor in dorsal-mediated repression in Drosophila, EMBO J., 12, 3193, 10.1002/j.1460-2075.1993.tb05988.x · DOI
- Kishimoto, 1997, The molecular nature of zebrafish swirl: BMP-2 function is essential during early dorsoventral patterning, Development, 124, 4457, 10.1242/dev.124.22.4457 · DOI
- Köster, 1991, Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity, Mech. Dev., 33, 191, 10.1016/0925-4773(91)90027-4 · DOI
- Kurihara, 1993, Murine bone morphogenetic protein-4 gene: existence of multiple promoters and exons for the 5′ untranslated region, Biochem. Biophys. Res. Commun., 192, 1049, 10.1006/bbrc.1993.1523 · DOI
- Nishimatsu, 1992, Genes for bone morphogenetic proteins are differentially transcribed in early amphibian embryos, Biochem. Biophys. Res. Commun., 186, 1487, 10.1016/S0006-291X(05)81574-8 · DOI
- Piccolo, 1996, Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4, Cell, 86, 589, 10.1016/S0092-8674(00)80132-4 · DOI
- Plessow, 1991, cDNA sequence of Xenopus laevis bone morphogenetic protein 2 (BMP-2), Biochim. Biophys. Acta, 1089, 280, 10.1016/0167-4781(91)90026-I · DOI
- Re'em-Kalma, 1995, Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development, Proc. Natl. Acad. Sci. USA, 92, 12141, 10.1073/pnas.92.26.12141 · DOI
- Richardson, 1994, XrelA, a Xenopus maternal and zygotic homologue of the p65 subunit of NF-kappa B. Characterisation of transcriptional properties in the developing embryo and identification of a negative interference mutant, Mech. Dev., 45, 173, 10.1016/0925-4773(94)90031-0 · DOI
- Richardson, 1995, Developmental effects of over-expression of normal and mutated forms of a Xenopus NF-kappa B homologue, Mech. Dev., 52, 165, 10.1016/0925-4773(95)00388-H · DOI
- Ryseck, 1992, RelB, a new rel family transcription activator that can interact with p50-NF-κB, Mol. Cell. Biol., 12, 674, 10.1128/MCB.12.2.674 · DOI
- Sasai, 1994, Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes, Cell, 79, 779, 10.1016/0092-8674(94)90068-X · DOI
- Schmidt, J., Francois, V., Bier, E., Kimelman, D., 1995a. Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning. Development 121, 4319–4328. · DOI
- Schmidt, J.E., Suzuki, A., Ueno, N., Kimelman, D., 1995b. Localized Bmp-4 mediates dorsal/ventral patterning in the early Xenopus embryo. Dev. Biol. 169, 37–50. · DOI
- Schulte-Merker, 1997, The zebrafish organizer requires chordino, Nature, 387, 862, 10.1038/43092 · DOI · Paper page
- Schwyter, 1995, The decapentaplegic core promoter region plays an integral role in the spatial control of transcription, Mol. Cell. Biol., 15, 3960, 10.1128/MCB.15.7.3960 · DOI
- Shoda, 1993, Presence of high molecular weight forms of BMP-2 in early Xenopus embryos, Growth Factors, 8, 165, 10.3109/08977199309011019 · DOI
- St. Johnston, 1990, Molecular organization of the decapentaplegic gene in Drosophila melanogaster, Genes Dev., 4, 1114, 10.1101/gad.4.7.1114 · DOI
- Suzuki, 1994, A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo, Proc. Natl. Acad. Sci. USA, 91, 10255, 10.1073/pnas.91.22.10255 · DOI
- Suzuki, 1995, Molecular cloning of cDNA encoding the Xenopus homolog of mammalian RelB, Nucleic Acids Res., 23, 4664, 10.1093/nar/23.22.4664 · DOI
- van den Wijngaard, 1996, Genomic organization of the human bone morphogenetic protein-4 gene: molecular basis for multiple transcripts, Biochem. Biophys. Res. Commun., 219, 789, 10.1006/bbrc.1996.0312 · DOI
- Wharton, 1993, An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo, Development, 117, 807, 10.1242/dev.117.2.807 · DOI
- Winnier, 1995, Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse, Genes Dev., 9, 2105, 10.1101/gad.9.17.2105 · DOI
- Zimmerman, 1996, The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein-4, Cell, 86, 599, 10.1016/S0092-8674(00)80133-6 · DOI
Cited by
Sorted by citations
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
Mehdipour, M., Skinner, C., Wong, N., Lieb, M., Liu, C., Etienne, J., Kato, C., Kiprov, D., Conboy, M. J., & Conboy, I. M. (2020) · Aging · doi:10.18632/aging.103418 · Cited by 115
Metadata
- Authors
- Metz, A., Knöchel, S., Büchler, P., Köster, M., & Knöchel, W.
- Venue
- Mechanisms of Development
- Publisher
- Elsevier BV
- Published
- 1998-06
- Volume
- 74
- Issue
- 1-2
- Pages
- 29-39
- ISSN
- 0925-4773
- Cited by
- 42
- References
- 2
- Language
- en
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