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Piperine derived from black pepper increases the plasma levels of coenzyme q10 following oral supplementation
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“Piperine also enhances the bioavailability of several other compounds including phenytoin, coenzyme Q10, theophylline, and propranolol (Bano et al., 1991; Badmaev et al., 2000; Pattanaik et al., 2006).”
From Curcuminoids Inhibit Multiple Human Cytochromes P450, UDP-Glucuronosyltransferase, and Sulfotransferase Enzymes, whereas Piperine Is a Relatively Selective CYP3A4 Inhibitor (2008) · cites this paper as Badmaev et al., 2000
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Research works printed but not linked: 23
- Govindarajan, V.S. (1977). Pepper–chemistry, technology, and quality evaluation. CRC Crit. Rev. Food Sci. Nutr. 115–250 · DOI
- Atal, 1981, Scientific evidence of the role on Ayurvedic herbals on bioavailability of drugs, J. Ethnopharm., 4, 229, 10.1016/0378-8741(81)90037-4 · DOI
- Zutshi, 1985, Influence of piperine on rifampicin blood levels in patients of pulmonary tuberculosis, J. Assoc. Physicians India, 33, 223
- Bano, 1991, The effect of piperine on bioavailability and pharmacokinetics of propranololol and theophylline in healthy volunteers, Eur. J. Clin. Pharmacol., 41, 615, 10.1007/BF00314996 · DOI · Paper page
- Bano, 1987, The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers, Planta Med, 53, 568, 10.1055/s-2006-962814 · DOI
- Atal, 1985, Biochemical basis of enhanced drug bioavailability by piperine, J. Pharmacol. Exp. Ther., 232, 258
- Badmaev, 1999, Piperine, an alkaloid derived from black pepper increases serum response of beta-carotene during 14-days of oral beta-carotene supplementation, Nutr. Res., 19, 381, 10.1016/S0271-5317(99)00007-X · DOI
- Okamoto, 1985, High performance liquid chromatography of coenzyme Q-related compounds and its application to biological materials, J. Chromatography, 342, 35, 10.1016/S0378-4347(00)84487-4 · DOI
- Jolliet, 1998, Plasma coenzymeQ10 concentrations in breast cancer, Int. J. Clin. Pharmacol. Ther., 36, 506
- McDonnell, 1996, Plasma ubiquinol/cholesterol ratios in patients with hyperlipidemia, those with diabetes mellitus and in patients requiring dialysis, Clin. Chim. Acta, 253, 117, 10.1016/0009-8981(96)06357-7 · DOI
- Karlsson, 1992, Plasma ubiquinone, alpha-tocopherol and cholesterol in man, Int. J. Vitam. Nutr. Res., 62, 160
- Soja, 1997, Treatment of congestive heart failure with coenzyme Q10, Mol. Aspects Med., 19, S159, 10.1016/S0098-2997(97)00042-3 · DOI
- Neuzil, 1997, Alpha-tocopherol hydroquinone is an efficient multifunctional inhibitor of radical-initiated oxidation of low-density lipoprotein lipids, Proc. Natl. Acad. Sci. USA, 94, 7885, 10.1073/pnas.94.15.7885 · DOI
- Suzuki, 1998, The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation, Diabetologia, 41, 584, 10.1007/s001250050950 · DOI
- Schulz, 1995, Coenzyme Q10 and nicotinamide in neural disorders, Exp. Neurol., 135, 279, 10.1016/0014-4886(95)90033-0 · DOI · Paper page
- Lewin, 1997, The effect of coenzyme Q10 on sperm motility and function, Mol. Aspects Med., 18, S213, 10.1016/S0098-2997(97)00036-8 · DOI
- Johansen, 1991, Coenzyme Q10, alpha-tocopherol and free cholesterol in HDL and LDL fractions, Ann. Med., 23, 649, 10.3109/07853899109148098 · DOI
- Kaplan, 1996, Determination of coenzyme Q in human plasma, Physiol. Res., 45, 39
- Tomono, 1986, Pharmacokinetic study of deuterium-labeled coenzyme Q10 in man, Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 536
- Annamalai, 1990, Effect of “Trikatu” and its individual components and piperine on gastrointestinal tracts, Indian Drugs, 27, 595
- Johri, 1992, Piperine-mediated changes in the permeability of intestinal epithelial cells, Biochem. Pharmacol., 43, 1401, 10.1016/0006-2952(92)90195-O · DOI
- Kawada, 1988, Some pungent principles of spices cause the adrenal medulla to secrete catecholamine in anesthetized rats, Proc. Soc. Exp. Biol. Med., 188, 229, 10.3181/00379727-188-2-RC1 · DOI
- Reanmongkol, 1988, Effects of piperine on bioenergetic functions of isolated rat liver mitochondria, Biochem. Pharmacol., 37, 753, 10.1016/0006-2952(88)90151-7 · DOI
Cited by
Black Pepper and its Pungent Principle-Piperine: A Review of Diverse Physiological Effects
Srinivasan, K. (2007) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390601062054 · Cited by 821
Volak, L. P., Ghirmai, S., Cashman, J. R., & Court, M. H. (2008) · Drug Metabolism and Disposition · doi:10.1124/dmd.108.020552 · Cited by 214
Metadata
- Authors
- Badmaev, V., Majeed, M., & Prakash, L.
- Venue
- The Journal of Nutritional Biochemistry
- Publisher
- Elsevier BV
- Published
- 2000-02
- Volume
- 11
- Issue
- 2
- Pages
- 109-113
- ISSN
- 0955-2863
- Cited by
- 90
- References
- 0
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.