Ubiquitination: RING for destruction?

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

Lorick, K. L., Jensen, J. P., Fang, S., Ong, A. M., Hatakeyama, S., & Weissman, A. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11364 · Cited by 1,151 · see citing works

The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase

Joazeiro, C. A. P., Wing, S. S., Huang, H.-K., Leverson, J. D., Hunter, T. R., & Liu, Y. (1999) · Science · doi:10.1126/science.286.5438.309 · Cited by 1,036 · see citing works

Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase

Kamura, T., Koepp, D. M., Conrad, M. N., Skowyra, D., Moreland, R. J., Iliopoulos, O., Lane, W. S., Kaelin, W. G., Elledge, S. J., Conaway, R. C., et al. (1999) · Science · doi:10.1126/science.284.5414.657 · Cited by 786 · see citing works

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

Wu, L. C., Wang, Z. W., Tsan, J. T., Spillman, M. A., Phung, A., Xu, X. L., Yang, M.-C. W., Hwang, L.-Y., Bowcock, A. M., & Baer, R. J. (1996) · Nature Genetics · doi:10.1038/ng1296-430 · Cited by 743 · see citing works

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

Jensen, D. E., Proctor, M. L., Marquis, S. T., Gardner, H. P., Ha, S. I., Chodosh, L. A., Ishov, A. M., Tommerup, N., Vissing, H., Sekido, Y., et al. (1998) · Oncogene · doi:10.1038/sj.onc.1201861 · Cited by 725 · see citing works

Association of p19ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53

Honda, R., & Yasuda, H. (1999) · The EMBO Journal · doi:10.1093/emboj/18.1.22 · Cited by 724 · see citing works

Does this have a familiar RING?

Saurin, A. J., Borden, K. L. B., Boddy, M. N., & Freemont, P. S. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)80017-x · Cited by 635 · see citing works

Reconstitution of G 1 Cyclin Ubiquitination with Complexes Containing SCF Grr1 and Rbx1

Skowyra, D., Koepp, D. M., Kamura, T., Conrad, M. N., Conaway, R. C., Conaway, J. W., Elledge, S. J., & Harper, J. W. (1999) · Science · doi:10.1126/science.284.5414.662 · Cited by 377 · see citing works

Ligand-induced Ubiquitination of the Epidermal Growth Factor Receptor Involves the Interaction of the c-Cbl RING Finger and UbcH7

Yokouchi, M., Kondo, T., Houghton, A., Bartkiewicz, M., Horne, W. C., Zhang, H., Yoshimura, A., & Baron, R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.44.31707 · Cited by 321 · see citing works

SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation

Duprez, E., Saurin, A. J., Desterro, J. M. P., et al. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.3.381 · Cited by 313 · see citing works

The RING Finger of c-Cbl Mediates Desensitization of the Epidermal Growth Factor Receptor

Waterman, H., Levkowitz, G., Alroy, I., & Yarden, Y. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.32.22151 · Cited by 306 · see citing works

Anatomy of TRAF2

Takeuchi, M., Rothe, M., & Goeddel, D. V. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.33.19935 · Cited by 301 · see citing works

Siah-1 N-Terminal RING Domain Is Required for Proteolysis Function, and C-Terminal Sequences Regulate Oligomerization and Binding to Target Proteins

Hu, G., & Fearon, E. R. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.724 · Cited by 241 · see citing works

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cyclePreprint

Freed, E., Lacey, K. R., Huie, P., et al. (1999) · Genes & Development · doi:10.1101/gad.13.17.2242 · Cited by 200 · see citing works

The E2–E3 interaction in the N‐end rule pathway: the RING‐H2 finger of E3 is required for the synthesis of multiubiquitin chain

Xie, Y., & Varshavsky, A. J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.23.6832 · Cited by 161 · see citing works

PRT1 of Arabidopsis thaliana encodes a component of the plant N-end rule pathway

Potuschak, T., Stary, S., Schlögelhofer, P., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.14.7904 · Cited by 126 · see citing works

Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 Inhibits Progression of Cells through Mitosis and from G 1 into S Phase of the Cell Cycle

Lomonte, P., & Everett, R. D. (1999) · Journal of Virology · doi:10.1128/jvi.73.11.9456-9467.1999 · Cited by 124 · see citing works

The Ubiquitin-conjugating Enzymes UbcH7 and UbcH8 Interact with RING Finger/IBR Motif-containing Domains of HHARI and H7-AP1

Moynihan, T. P., Ardley, H. C., Nuber, U. A., Rose, S. A., Jones, P. F., Markham, A. F., Scheffner, M., & Robinson, P. A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.43.30963 · Cited by 117 · see citing works

A RING‐H2 finger motif is essential for the function of Der3/Hrd1 in endoplasmic reticulum associated protein degradation in the yeast Saccharomyces cerevisiae

Bordallo, J., & Wolf, D. H. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00362-2 · Cited by 57 · see citing works

A family of structurally related RING finger proteins interacts specificallywith the ubiquitin‐conjugating enzyme UbcM41

Martínez-Noël, G., Niedenthal, R. K., Tamura, T., & Harbers, K. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00823-6 · Cited by 52 · see citing works

Identification of ubiquitin ligases required for skeletal muscle atrophy.

Bodine, S. C., Latres, E., Baumhueter, S., Lai, V. K.-M., Nunez, L., Clarke, B. A., Poueymirou, W. T., Panaro, F. J., Na, E., Dharmarajan, K., et al. (2001) · Science · doi:10.1126/science.1065874 · Cited by 3,521 · see citing works

RING Finger Proteins

Joazeiro, C. A. P., & Weissman, A. M. (2000) · Cell · doi:10.1016/s0092-8674(00)00077-5 · Cited by 1,249 · see citing works

Herpes Simplex Virus Type 1 Immediate-Early Protein ICP0 and Its Isolated RING Finger Domain Act as Ubiquitin E3 Ligases In Vitro

Boutell, C., Sadis, S., & Everett, R. D. (2002) · Journal of Virology · doi:10.1128/jvi.76.2.841-850.2002 · Cited by 386 · see citing works

Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function

James, L. C., Keeble, A. H., Khan, Z., Rhodes, D. A., & Trowsdale, J. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609174104 · Cited by 386 · see citing works

Limb-Girdle Muscular Dystrophy Type 2H Associated with Mutation in TRIM32, a Putative E3-Ubiquitin–Ligase Gene

Frosk, P., Weiler, T., Nylen, E., Sudha, T., Greenberg, C. R., Morgan, K., Fujiwara, T. M., & Wrogemann, K. (2002) · The American Journal of Human Genetics · doi:10.1086/339083 · Cited by 261 · see citing works

Time to recurrence and survival in serous ovarian tumors predicted from integrated genomic profiles

Mankoo, P. K., Shen, R., Schultz, N., Levine, D. A., & Sander, C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024709 · Cited by 104 · see citing works

Identification of Genes Induced in Peripheral Nerve after Injury

Araki, T., Nagarajan, R., & Milbrandt, J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104271200 · Cited by 76 · see citing works

The E3 ubiquitin ligases regulate inflammation in cardiovascular diseases

Chen, X., Ma, J., Wang, Z. P., et al. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.02.008 · Cited by 28 · see citing works

Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C

Paluda, A., Middleton, A. J., Roßig, C., Mace, P. D., & Day, C. L. (2022) · Nature Communications · doi:10.1038/s41467-022-28782-y · Cited by 32 · see citing works

Functional analysis of the ubiquitin ligase Hrd1p with the ubiquitin -conjugating enzyme Ubc7p

Bazirgan, O. A. (2007) · eScholarship (California Digital Library)

Analysis of ubiquitin E3 ligase activity using selective polyubiquitin binding proteins

Marblestone, J. G., LaRocque, J. P., Mattern, M. R., et al. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2012.06.013 · Cited by 18 · see citing works

Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains

Liu, S., Chen, Y., Li, J., Huang, T., Tarasov, S. G., King, A., Weissman, A. M., Byrd, R. A., & Das, R. (2012) · Structure · doi:10.1016/j.str.2012.09.020 · Cited by 31 · see citing works