Non-homologous end joining as a mechanism of DNA repair

DNA double-strand breaks: signaling, repair and the cancer connection

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Artemis, a Novel DNA Double-Strand Break Repair/V(D)J Recombination Protein, Is Mutated in Human Severe Combined Immune Deficiency

Moshous, D., Callebaut, I., de Chasseval, R., Corneo, B., Cavazzana, M., Deist, F. L., Tezcan, İ., Sanal, Ö., Bertrand, Y., Philippe, N., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00309-9 · Cited by 912 · see citing works

Partners and pathways

Haber, J. E. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(00)02022-9 · Cited by 564 · see citing works

DNA double strand break repair in mammalian cells

Karran, P. (2000) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00069-1 · Cited by 447 · see citing works

Binding of Inositol Phosphate to DNA-PK and Stimulation of Double-Strand Break Repair

Hanakahi, L. A., Bartlet‐Jones, M., Chappell, C., Pappin, D., & West, S. C. (2000) · Cell · doi:10.1016/s0092-8674(00)00061-1 · Cited by 263 · see citing works

Sterility of Drosophila with Mutations in the Bloom Syndrome Gene--Complementation by Ku70

Kusano, K., Johnson-Schlitz, D. M., & Engels, W. R. (2001) · Science · doi:10.1126/science.291.5513.2600 · Cited by 112 · see citing works

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

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Recombinational DNA repair and human disease

Thompson, L. H., & Schild, D. (2002) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/s0027-5107(02)00224-5 · Cited by 417 · see citing works

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

Mitra, J., Guerrero, E. N., Hegde, P. M., Liachko, N. F., Wang, H., Vasquez, V., Gao, J., Pandey, A., Taylor, J. P., Kraemer, B. C., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1818415116 · Cited by 305 · see citing works

The MRN complex: coordinating and mediating the response to broken chromosomes

van den Bosch, M., Bree, R. T., & Lowndes, N. F. (2003) · The EMBO Reports · doi:10.1038/sj.embor.embor925 · Cited by 289 · see citing works

Advances in therapeutic CRISPR/Cas9 genome editing

Savić, N., & Schwank, G. (2016) · Translational Research · doi:10.1016/j.trsl.2015.09.008 · Cited by 257 · see citing works

Focus on UV-Induced DNA Damage and Repair—Disease Relevance and Protective Strategies

Kciuk, M., Marciniak, B., Mojzych, M., & Kontek, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197264 · Cited by 168 · see citing works

Investigating the mechanism of chromosomal deletion: characterization of 39 deletion breakpoints in introns 47 and 48 of the human dystrophin gene

Toffolatti, L., Cardazzo, B., Nobile, C., Danieli, G. A., Gualandi, F., Muntoni, F., Abbs, S., Zanetti, P., Angelini, C., Ferlini, A., et al. (2002) · Genomics · doi:10.1006/geno.2002.6861 · Cited by 80 · see citing works

T7 RNA polymerase bypass of large gaps on the template strand reveals a critical role of the nontemplate strand in elongation

Zhou, W., Reines, D., & Doetsch, P. W. (1995) · Cell · doi:10.1016/0092-8674(95)90030-6 · Cited by 60 · see citing works

Probing DNA Binding, DNA Opening and Assembly of a Downstream Clamp During Transcription Initiation by E. coli RNA Polymerase at the λPR Promoter

Drennan, A. C., Gries, T. J., Heitkamp, S. E., et al. (2011) · Biophysical Journal · doi:10.1016/j.bpj.2010.12.557

A Mechanism of Nucleotide Misincorporation during Transcription due to Template-Strand Misalignment

Pomerantz, R. T., Temiakov, D., Anikin, M., Vassylyev, D. G., & McAllister, W. T. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.08.014 · Cited by 31 · see citing works

Structural origins of Escherichia coli RNA polymerase open promoter complex stability

Saecker, R. M., Chen, J., Chiu, C. E., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2112877118 · Cited by 43 · see citing works

Transcription Blockage by Bulky End Termini at Single-Strand Breaks in the DNA Template: Differential Effects of 5′ and 3′ Adducts

Neil, A. J., Belotserkovskii, B. P., & Hanawalt, P. C. (2012) · Biochemistry · doi:10.1021/bi301240y · Cited by 34 · see citing works