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The Crystal Structure of Coxsackievirus B3 RNA-Dependent RNA Polymerase in Complex with Its Protein Primer VPg Confirms the Existence of a Second VPg Binding Site on Picornaviridae Polymerases

Gruez, A., Selisko, B., Roberts, M. M., Bricogne, G., Bussetta, C., Jabafi, I., Coutard, B., Palma, A. M. D., Neyts, J. H., & Canard, B. (2008) · Journal of Virology · doi:10.1128/jvi.00631-08 · Cited by 87 · see citing works

Kinetic Mechanism of DNA Polymerases: Contributions of Conformational Dynamics and a Third Divalent Metal Ion

Raper, A. T., Reed, A. J., & Suo, Z. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00685 · Cited by 83 · see citing works

Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution

Zhao, C., & Pyle, A. M. (2016) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3224 · Cited by 83 · see citing works

Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication

Hsu, G. W., Huang, X., Luneva, N. P., Geacintov, N. E., & Beese, L. S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m411276200 · Cited by 82 · see citing works

Transient State Kinetics of Transcription Elongation by T7 RNA Polymerase

Anand, V. S., & Patel, S. S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m608180200 · Cited by 80 · see citing works

DNA Polymerase ε: A Polymerase of Unusual Size (and Complexity)

Pursell, Z. F., & Kunkel, T. A. (2008) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)00004-4 · Cited by 79 · see citing works

Loss of DNA Polymerase β Stacking Interactions with Templating Purines, but Not Pyrimidines, Alters Catalytic Efficiency and Fidelity

Beard, W. A., Shock, D. D., Yang, X., DeLauder, S. F., & Wilson, S. H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m107286200 · Cited by 74 · see citing works

Observing Translesion Synthesis of an Aromatic Amine DNA Adduct by a High-fidelity DNA Polymerase

Hsu, G. W., Kiefer, J. R., Burnouf, D., Bécherel, O. J., Fuchs, R. P., & Beese, L. S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m409224200 · Cited by 72 · see citing works

Inhibition of Reverse Transcription In Vivo by Elevated Manganese Ion Concentration

Bolton, E. C., Mildvan, A. S., & Boeke, J. D. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00495-1 · Cited by 72 · see citing works

Structural basis of error‐prone replication and stalling at a thymine base by human DNA polymerase ι

Kirouac, K. N., & Ling, H. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.122 · Cited by 71 · see citing works

Mechanistic Comparison of High-Fidelity and Error-Prone DNA Polymerases and Ligases Involved in DNA Repair

Showalter, A. K., Lamarche, B. J., Bakhtina, M., Su, M., Tang, K., & Tsai, M. (2006) · Chemical Reviews · doi:10.1021/cr040487k · Cited by 71 · see citing works

A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase

Chinnaswamy, S., Yarbrough, I., Palaninathan, S. K., Ranjith-Kumar, C. T., Vijayaraghavan, V., Demeler, B., Lemon, S. M., Sacchettini, J. C., & Kao, C. C. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801490200 · Cited by 68 · see citing works

Evolution of replication machines

Yao, N. Y., & O’Donnell, M. E. (2015) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2015.1125845 · Cited by 68 · see citing works

Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis

Malik, R., Kopylov, M., Gómez-Llorente, Y., Jain, R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena‐Belandia, I., & Aggarwal, A. K. (2020) · Nature Structural & Molecular Biology · doi:10.1038/s41594-020-0476-7 · Cited by 67 · see citing works

Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis

Dutta, S., Li, Y., Johnson, D. E., Dzantiev, L., Richardson, C. C., Romano, L. J., & Ellenberger, T. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406516101 · Cited by 66 · see citing works

Dpo4 is hindered in extending a G·T mismatch by a reverse wobble

Trincão, J., Johnson, R. E., Wolfle, W. T., Escalante, C. R., Prakash, S., Prakash, L., & Aggarwal, A. K. (2004) · Nature Structural & Molecular Biology · doi:10.1038/nsmb755 · Cited by 63 · see citing works

Structure–Function Studies of DNA Polymerase λ

Bębenek, K., Pedersen, L. C., & Kunkel, T. A. (2014) · Biochemistry · doi:10.1021/bi4017236 · Cited by 65 · see citing works

An Incoming Nucleotide Imposes an anti to syn Conformational Change on the Templating Purine in the Human DNA Polymerase-ι Active Site

Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S., & Aggarwal, A. K. (2006) · Structure · doi:10.1016/j.str.2006.01.010 · Cited by 65 · see citing works

The p12 Subunit of Human Polymerase δ Modulates the Rate and Fidelity of DNA Synthesis

Meng, X., Zhou, Y., Lee, E. Y. C., Lee, M., & Frick, D. N. (2010) · Biochemistry · doi:10.1021/bi100042b · Cited by 61 · see citing works

Investigation of the DNA-dependent cyclohexenyl nucleic acid polymerization and the cyclohexenyl nucleic acid-dependent DNA polymerization

Kempeneers, V. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki695 · Cited by 60 · see citing works

Techniques used to study the DNA polymerase reaction pathway

Joyce, C. M. (2009) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2009.07.021 · Cited by 60 · see citing works

Functional Evidence for a Small and Rigid Active Site in a High Fidelity DNA Polymerase

Kim, T. W., Brieba, L. G., Ellenberger, T., & Kool, E. T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m510744200 · Cited by 60 · see citing works

Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I

Markiewicz, R. P., Vrtis, K. B., Rueda, D., & Romano, L. J. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks523 · Cited by 59 · see citing works

Using the Hepatitis C Virus RNA-Dependent RNA Polymerase as a Model to Understand Viral Polymerase Structure, Function and Dynamics

Sesmero, E., & Thorpe, I. F. (2015) · Viruses · doi:10.3390/v7072808 · Cited by 59 · see citing works

The Mutational Specificity of the Dbh Lesion Bypass Polymerase and Its Implications

Potapova, O., Grindley, N. D. F., & Joyce, C. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202607200 · Cited by 59 · see citing works

Bumps in the road: how replicative DNA polymerases see DNA damage

Hogg, M., Wallace, S. S., & Doublié, S. (2005) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2005.01.014 · Cited by 58 · see citing works

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody fab fragment at 2.8 Å resolution

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Rational design of polymerase inhibitors as antiviral drugs

Öberg, B. F. (2006) · Antiviral Research · doi:10.1016/j.antiviral.2006.05.012 · Cited by 55 · see citing works

Structural Insights into Mechanisms of Catalysis and Inhibition in Norwalk Virus Polymerase

Zamyatkin, D. F., Parra, F., Martín-Alonso, J. M., Harki, D. A., Peterson, B. R., Grochulski, P., & Ng, K. K.-S. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709563200 · Cited by 139 · see citing works

The structure and functions of HIV-1 polymerase and the development of its inhibitors

Liu, X. (2006) · Zhongguo yaowu huaxue zazhi

HIV-1 Reverse Transcriptase: Structure Predictions for the Polymerase Domain

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