The DOI matches its Crossref record; 172 of the 176 references it cites were found in a registry or an index.
Effects of Cyclic GMP on Smooth Muscle Relaxation
Abstract
Cyclic GMP levels within smooth muscle are affected then by a number of different pathways. Physiologically NO and ANF are probably the two most important regulators for smooth muscle function, but a variety of other mediators and pharmacological agents may also influence this system. Because of the important role that cyclic GMP plays in the control of smooth muscle tone, which clearly includes vascular smooth muscle, it is now and will continue to be in the future an important physiological and biochemical target for research and a pharmacological target for therapeutic agents.
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“Like XO and AO, the molybdopterin cofactor of sulfite oxidase is able to catalyze nitrite reduction to produce NO (Table 4) (990).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [990]
In the citing paper
“Subsequently, several reports have shown that all mammalian Mo-containing enzymes [XO, aldehyde oxidase (AO), sulfite oxidase, and the mitochondrial amidoxime-reducing component (mARC)] are able to reduce nitrite at different intrinsic rates (Table 4) (575, 880, 990).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [990]
Citations
Cites
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Self-citation
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Fujita, S., Yoshida, Y., Islam, O., Ma, X., Fujioka, M., Ito, M., Nakano, T., Aizawa, Y., Imai, S., & Higuchi, H. (1999) · Journal of Vascular Research · doi:10.1159/000025658 · Cited by 1
El‐Sehemy, A. (2014) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3mt2g · Cited by 1
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Ahn, E., & Bae, J. (2026) · Natural Product Sciences · doi:10.20307/nps.2026.32.1.1
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Metadata
- Authors
- Warner, T. D., Mitchell, J. A., Sheng, H., & Murad, F.
- Affiliations
- St Bartholomew's Hospital (GB)
- University of California, Los Angeles (US)
- Venue
- Advances in Pharmacology
- Publisher
- Elsevier
- Published
- 1994
- Volume
- 26
- Pages
- 171-194
- ISSN
- 1054-3589 (ISSN-L)
- OpenAlex
- W1437168237
- Cited by
- 117
- References
- 176
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 6 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 4 · 2017: 6 · 2016: 2 · 2015: 4 · 2014: 3 · 2013: 3 · 2012: 5
- FWCI
- 3.34
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Advances in pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phosphodiesterase function and regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Keywords
- cyclic GMP, smooth muscle relaxation, guanylate cyclase, nitric oxide, atrial natriuretic peptide, smooth muscle tone, second messengers
- MeSH terms
- Animals, Cyclic GMP, Guanylate Cyclase, Humans, Isoenzymes, Muscle Relaxation, Muscle, Smooth
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