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Cited by 51Genomics and Chromatin DynamicsT-cell and B-cell ImmunologyDNA Repair Mechanisms

ETS Protein–Dependent Accessibility Changes at the Immunoglobulin μ Heavy Chain Enhancer

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Nikolajczyk, Barbara S, Sanchez, J.Aquiles, Sen, Ranjan·1999·Immunity
DOI 10.1016/s1074-7613(00)80077-1
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  • PU.1 has chromatin opening activity in B cells, can eject nucleosomes in macrophage lines, and causes rapid increases in ATAC accessibility at sites it occupies when introduced into Scid.adh.2C2 cells.

    “This is consistent with PU.1's activity as a site-specific chromatin opening factor in B cells (96, 97), with the ability of PU.1 to eject nucleosomes from sites where it binds in macrophage lines (12), and with its ability to cause rapid increases in ATAC accessibility at the sites it occupies when introduced into Scid.adh.2C2 cells (85).”

    From Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development (2019) · cites this paper as [96]

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Research works printed but not linked: 20

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Cited by

Sorted by citations

Authors
Nikolajczyk, B. S., Sanchez, J. A., & Sen, R.
Affiliations
Brandeis University (US)
Corresponding author
Sen, Ranjan
ORCID
Venue
Immunity
Publisher
Elsevier BV
Published
1999-07
Volume
11
Issue
1
Pages
11-20
ISSN
1074-7613 (ISSN-L)
DOI
10.1016/s1074-7613(00)80077-1
OpenAlex
W2017606650
Cited by
51
References
2
Citations by year
2025: 1 · 2024: 1 · 2021: 1 · 2020: 1 · 2019: 1 · 2017: 2 · 2014: 1 · 2012: 2
FWCI
1.14
Type
journal article
Language
en
Open access
Licence
Locations
  • Immunity (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of General Medical Sciences (GM-38925)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
  • Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
Keywords
chromatin accessibility, ETS1, PU.1, V(D)J recombination, pro-T cells, IGH locus, transcriptional regulation
MeSH terms
Proto-Oncogene Protein Spi-1, Animals, Chromatin, DNA Restriction Enzymes, Enhancer Elements, Genetic, Gene Expression Regulation, Immunoglobulin Heavy Chains, Immunoglobulin mu-Chains, Protein Binding, Proto-Oncogene Proteins, Receptors, Antigen, B-Cell, Stem Cells, T-Lymphocytes, Transcription Factors, Transcription, Genetic, Xenopus, Gene Rearrangement, B-Lymphocyte, Heavy Chain, Trans-Activators, 3T3 Cells, Proto-Oncogene Proteins c-ets, Proto-Oncogene Protein c-ets-1, Mice

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