Cited by 198T-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesDiabetes and associated disorders

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Abstract

The establishment and maintenance of immunological tolerance entails both central and peripheral mechanisms. The latter have been highlighted in the past several years, mostly because of great interest in the activities of regulatory T cells. However, an important role for central tolerance mechanisms has been reemphasized by recent results on human autoimmune diseases, including APECED and type 1 diabetes.

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Metadata

Authors
Mathis, D., & Benoist, C.
Affiliations
Brigham and Women's Hospital (US)
Corresponding author
Benoist, Christophe
Venue
Immunity
Publisher
Elsevier BV
Published
2004-05
Volume
20
Issue
5
Pages
509-516
ISSN
1074-7613 (ISSN-L)
OpenAlex
W2047784036
Cited by
198
References
0
Citations by year
2026: 1 · 2024: 2 · 2023: 4 · 2022: 3 · 2021: 4 · 2020: 4 · 2019: 3 · 2018: 4 · 2017: 1 · 2016: 5 · 2015: 2 · 2014: 9 · 2013: 11 · 2012: 11
FWCI
2.27
Type
journal article
Language
en
Open access
Locations
  • Immunity (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
  • Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
Keywords
central tolerance, peripheral tolerance, immune tolerance, regulatory T cells, autoimmune disease, APECED, type 1 diabetes, autoimmunity
MeSH terms
AIRE Protein, Animals, Autoimmune Diseases, Cell Differentiation, Humans, Immune Tolerance, Lymphocyte Activation, T-Lymphocytes, Thymus Gland, Transcription Factors

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