Mammalian Microsomal Cytochrome P450 Monooxygenase
Williams, Pamela A., Cosme, Jose, Sridhar, Vandana, Johnson, Eric F., McRee, Duncan E.·2000·Molecular Cell
Cited by (707)
Items 201–300 of 707
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- Hydroxylation of Limonene Enantiomers and Analogs by Recombinant (−)-Limonene 3- and 6-Hydroxylases from Mint (Mentha) Species: Evidence for Catalysis within Sterically Constrained Active SitesMatthias Wüst, Dawn B Little, Michel Schalk, Rodney Croteau · 2001 · Archives of Biochemistry and Biophysics
- Molecular analysis of two cytochrome P450 monooxygenase genes required for paxilline biosynthesis in Penicillium paxilli, and effects of paxilline intermediates on mammalian maxi-K ion channelsLisa McMillan, R. L. Carr, Carolyn A. Young, Jonathan W. Astin, Rohan G. T. Lowe, Emily J. Parker, Geoffrey B. Jameson, Sarah C. Finch, Christopher O. Miles, Owen B. McManus et al. · 2003 · Molecular Genetics and Genomics
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- CYP3A4 Gene Polymorphisms Influence Testosterone 6β-hydroxylationNorie Murayama, Takahiro Nakamura, Mayumi Saeki, Akiko Soyama, Yoshiro Saito, Kimie Sai, Seiichi Ishida, Osamu Nakajima, Masaya Itoda, Yasuo Ohno et al. · 2002 · Drug Metabolism and Pharmacokinetics
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- Identification of the Amino Acid Residue of CYP27B1 Responsible for Binding of 25-Hydroxyvitamin D3 Whose Mutation Causes Vitamin D-dependent Rickets Type 1Keiko Yamamoto, Eriko Uchida, Naoko Urushino, Toshiyuki Sakaki, Norio Kagawa, Natsumi Sawada, Masaki Kamakura, Shigeaki Kato, Kuniyo Inouye, Sachiko Yamada · 2005 · Journal of Biological Chemistry
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- Computational Identification and Systematic Classification of Novel Cytochrome P450 Genes in Salvia miltiorrhizaHaimei Chen, Bin Wu, David R. Nelson, Kai Wu, Chang Liu · 2014 · PLoS ONE
- Human Enzymes for Organic SynthesisMargit Winkler, Martina Geier, Steven Paul Hanlon, Bernd Nidetzky, Anton Glieder · 2018 · Angewandte Chemie International Edition
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- Structures of Cytochrome P450 EnzymesT.L. Poulos, Eric F. Johnson · 2007 · Springer eBooks
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- Molecular Modeling of Cytochrome P450 1A1: Enzyme-Substrate Interactions and Substrate Binding AffinitiesGrażyna D. Szklarz, Mark D. Paulsen · 2002 · Journal of Biomolecular Structure and Dynamics
- Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenaseJ.‐S. Chen, May R. Berenbaum, Mary A. Schuler · 2002 · Insect Molecular Biology
- Structure-Function Analysis of Vitamin D 24-Hydroxylase (CYP24A1) by Site-Directed Mutagenesis: Amino Acid Residues Responsible for Species-Based Difference of CYP24A1 between Humans and RatsHiromi Hamamoto, Tatsuya Kusudo, Naoko Urushino, Hiroyuki Masuno, Keiko Yamamoto, Sachiko Yamada, Masaki Kamakura, Miho Ohta, Kuniyo Inouye, Toshiyuki Sakaki · 2006 · Molecular Pharmacology
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- Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray CrystallographyPaul Ross Wilderman, Manish B. Shah, Tong Liu, Sheng Li, Simon Hsu, Arthur G. Roberts, David R. Goodlett, Qinghai Zhang, Virgil L. Woods, Charles David Stout et al. · 2010 · Journal of Biological Chemistry
- The endocrine disruptor effect of the herbicides atrazine and glyphosate on Biomphalaria alexandrina snailsNahla E. Omran, Wesam Mohamed Salama · 2013 · Toxicology and Industrial Health
- Interaction of Cytochrome P450 3A4 and UDP-Glucuronosyltransferase 2B7: Evidence for Protein-Protein Association and Possible Involvement of CYP3A4 J-Helix in the InteractionShuso Takeda, Yuji Ishii, Megumi Iwanaga, Arief Nurrochmad, Yuji Ito, Peter I. Mackenzie, Kiyoshi Nagata, Yasushi Yamazoe, Kazuta Oguri, Hideyuki Yamada · 2009 · Molecular Pharmacology
- Cholesterol-metabolizing cytochromes P450: implications for cholesterol loweringIrina A. Pikuleva · 2008 · Expert Opinion on Drug Metabolism & Toxicology
- Autoantibodies Against CYP2D6 and Other Drug-Metabolizing Enzymes in Autoimmune Hepatitis Type 2Takaharu Mizutani, Masakazu Shinoda, Yuta Tanaka, Takuya Kuno, Asuka Hattori, Toru Usui, Nayumi Kuno, Takashi Osaka · 2005 · Drug Metabolism Reviews
- Kinetic and Molecular Analysis of 5-Epiaristolochene 1,3-Dihydroxylase, a Cytochrome P450 Enzyme Catalyzing Successive Hydroxylations of SesquiterpenesShunji Takahashi, Yuxin Zhao, Paul E. O’Maille, Bryan T. Greenhagen, Joseph P. Noel, Robert M. Coates, Joe Chappell · 2004 · Journal of Biological Chemistry
- Novel Mutations in CYP21 Detected in Individuals with HyperandrogenismSvetlana Lajić, Séverine Clauin, Tiina Robins, Patrick Vexiau, Hélène Blanché, Christine Bellanné‐Chantelot, Anna Wedell · 2002 · The Journal of Clinical Endocrinology & Metabolism
- Transcriptome Assembly and Systematic Identification of Novel Cytochrome P450s in Taxus chinensisWeifang Liao, Shengying Zhao, Meng Zhang, Kaige Dong, Ying Chen, Chunhua Fu, Longjiang Yu · 2017 · Frontiers in Plant Science
- Engineering Plant Cytochrome P450s for Enhanced Synthesis of Natural Products: Past Achievements and Future PerspectivesYi Shang, Sanwen Huang · 2019 · Plant Communications
- Metabolism of coumarin by human P450s: A molecular modelling studyDavid F.V. Lewis, Yuko Ito, Brian G. Lake · 2005 · Toxicology in Vitro
- Functional characterisation of an engineered multidomain human P450 2E1 by molecular LegoM. Fairhead, Silva Giannini, Elizabeth M. J. Gillam, Gianfranco Gilardi · 2005 · JBIC Journal of Biological Inorganic Chemistry
- Thermodynamic and Biophysical Characterization of Cytochrome P450 BioI from Bacillus subtilisRachel J. Lawson, David Leys, Michael J. Sutcliffe, Carol A. Kemp, Myles R. Cheesman, Susan J. Smith, John Clarkson, W. Ewen Smith, Ihtshamul Haq, John B. Perkins et al. · 2004 · Biochemistry
- The molecular and enzyme kinetic basis for the diminished activity of the cytochrome P450 2D6.17 (CYP2D6.17) variantTashinga E. Bapiro, Julia A. Hasler, Marianne Ridderström, Collen Mutowembwa Masimirembwa · 2002 · Biochemical Pharmacology
- Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymesDavid F.V Lewis · 2002 · Archives of Biochemistry and Biophysics
- Analysis of Human Cytochrome P450 2C8 Substrate Specificity Using a Substrate Pharmacophore and Site-Directed MutantsArmelle Melet, Cristina Marques‐Soares, G. Schoch, Anne‐Christine Macherey, Maryse Jaouen, Patrick M. Dansette, Marie‐Agnès Sari, Eric F. Johnson, Daniel Mansuy · 2004 · Biochemistry
- A Bioinformatics Approach for the Phenotype Prediction of Nonsynonymous Single Nucleotide Polymorphisms in Human Cytochromes P450Linlin Wang, Yong Li, Shufeng Zhou · 2009 · Drug Metabolism and Disposition
- POSSIBLE PATHWAY(S) OF TESTOSTERONE EGRESS FROM THE ACTIVE SITE OF CYTOCHROME P450 2B1: A STEERED MOLECULAR DYNAMICS SIMULATIONWeihua Li, Hong Shu Liu, Emily E. Scott, Frauke Gräter, James R. Halpert, Xiaoming Luo, Jianhua Shen, Hualiang Jiang · 2005 · Drug Metabolism and Disposition
- Atomic-level description of protein–lipid interactions using an accelerated membrane modelJavier L. Baylon, Josh V. Vermaas, Melanie P. Muller, Mark J. Arcario, Taras V. Pogorelov, Emad Tajkhorshid · 2016 · Biochimica et Biophysica Acta (BBA) - Biomembranes
- CYP2J2 Molecular Recognition: A New Axis for Therapeutic DesignAditi Das, Austin T. Weigle, William R. Arnold, Justin S. Kim, Lauren N. Carnevale, Hannah C. Huff · 2020 · Pharmacology & Therapeutics
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- Recent advances in P450 researchJudy L. Raucy, Scott W. Allen · 2001 · The Pharmacogenomics Journal
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- Engineering and assaying of cytochrome P450 biocatalystsKersten S. Rabe, Valérie J. Gandubert, Mark Spengler, Michael Erkelenz, Christof M. Niemeyer · 2008 · Analytical and Bioanalytical Chemistry
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- Membrane-Protein Interactions Contribute to Efficient 27-Hydroxylation of Cholesterol by Mitochondrial Cytochrome P450 27A1Dilyara A. Murtazina, Andrei V. Puchkaev, Catherine H. Schein, Numan Oezguen, Werner A. Braun, Amit Nanavati, Irina A. Pikuleva · 2002 · Journal of Biological Chemistry
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- Mutation of Tyrosine 190 to Alanine Eliminates the Inactivation of Cytochrome P450 2B1 by PeroxynitriteHsia-lien Lin, Ute M. Kent, Haoming Zhang, Lucy A. Waskell, Paul F. Hollenberg · 2003 · Chemical Research in Toxicology
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- CYP2C8 Exists as a Dimer in Natural MembranesGang Hu, Eric F. Johnson, BYRON W. KEMPER · 2010 · Drug Metabolism and Disposition
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