Mammalian Microsomal Cytochrome P450 Monooxygenase

Cited by (707)

Items 301–400 of 707

1. Methods for Predicting Human Drug Metabolism
   Larry J. Jolivette, Sean Ekins · 2006 · Advances in clinical chemistry
2. Structural evidence for a functionally relevant second camphor binding site in P450cam: Model for substrate entry into a P450 active site
   Huili Yao, Christopher McCullough, Aurora D. Costache, Phani Kumar Pullela, Daniel S. Sem · 2007 · Proteins Structure Function and Bioinformatics
3. Molecular modelling of human CYP1B1 substrate interactions and investigation of allelic variant effects on metabolism
   David F.V. Lewis, Elizabeth M. J. Gillam, Steven Albert Everett, Tsutomu Shimada · 2003 · Chemico-Biological Interactions
4. Influence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6
   Graham P. Hayhurst, Jacky HARLOW, Joey CHOWDRY, Esme GROSS, Emma N. Hilton, Martin S Lennard, Geoffrey T. Tucker, S. Wynne Ellis · 2001 · Biochemical Journal
5. Importance of amine pKa and distribution coefficient in the metabolism of fluorinated propranolol derivatives. Preparation, identification of metabolite regioisomers, and metabolism by CYP2D6.
   Alana L. Upthagrove, Wendel Lane Nelson · 2001 · PubMed
6. Cluster Formation of Anchored Proteins Induced by Membrane-Mediated Interaction
   Shuangyang Li, Xianren Zhang, Wenchuan Wang · 2010 · Biophysical Journal
7. The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen
   Marie Stiborová, Bruno Sopko, Petr Hodek, Eva Frei, Heinz H. Schmeiser, Jiřı́ Hudeček · 2005 · Cancer Letters
8. Charge-Dependent Sidedness of Cytochrome P450 Forms Studied by Quartz Crystal Microbalance and Atomic Force Microscopy
   John B. Schenkman, Ingela Jansson, YURI M. LVOV, James F. Rusling, Salah Boussaad, Nongjian J. Tao · 2001 · Archives of Biochemistry and Biophysics
9. Incorporation of charged residues in the CYP2J2 F-G loop disrupts CYP2J2–lipid bilayer interactions
   Daniel R. McDougle, Javier L. Baylon, Daryl D. Meling, Amogh Kambalyal, Yelena V. Grinkova, Jared Hammernik, Emad Tajkhorshid, Aditi Das · 2015 · Biochimica et Biophysica Acta (BBA) - Biomembranes
10. Picturing the Membrane‐assisted Choreography of Cytochrome P450 with Lipid Nanodiscs
    Carlo Barnaba, Ayyalusamy Ramamoorthy · 2018 · ChemPhysChem
11. CYP2C9 Structure−Metabolism Relationships: Substrates, Inhibitors, and Metabolites
    Marie M. Ahlström, Marianne Ridderström, Ismael Zamora · 2007 · Journal of Medicinal Chemistry
12. 2D SMARTCyp Reactivity-Based Site of Metabolism Prediction for Major Drug-Metabolizing Cytochrome P450 Enzymes
    Ruifeng Liu, Jin Liu, GJ Tawa, Anders Wallqvist · 2012 · Journal of Chemical Information and Modeling
13. Membrane Binding and Substrate Access Merge in Cytochrome P450 7A1, a Key Enzyme in Degradation of Cholesterol
    Kazuo Nakayama, Andrei V. Puchkaev, Irina A. Pikuleva · 2001 · Journal of Biological Chemistry
14. Contradictory effects of mitochondria‐ and non‐mitochondria‐targeted antioxidants on hepatocarcinogenesis by altering DNA repair in mice
    Bibo Wang, Jing Fu, Ting Yu, An Xu, Wenhao Qin, Zhishi Yang, Yao Chen, Hongyang Wang · 2017 · Hepatology
15. Crystal structure of CYP76AH1 in 4-PI-bound state from Salvia miltiorrhiza
    Mingyue Gu, Mingzhu Wang, Juan Guo, Chao Shi, Jie Deng, Luqi Huang, Lixin Huang, Zhenzhan Chang · 2019 · Biochemical and Biophysical Research Communications
16. p.H62L, a Rare Mutation of the CYP21 Gene Identified in Two Forms of 21-Hydroxylase Deficiency
    Rita Menassa, Véronique Tardy, F Despert, Claire Morel Bouvattier, J. P. Brossier, Maryse Cartigny, Yves Morel · 2008 · The Journal of Clinical Endocrinology & Metabolism
17. Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions
    D.F.V Lewis, Brian G. Lake, Michael G. Bird, George D. Loizou, Maurice Dickins, Peter S. Goldfarb · 2003 · Toxicology in Vitro
18. Characterization of the CYP3A4 Active Site by Homology Modeling
    Toshimasa Tanaka, Teruaki Okuda, Yoshio Yamamoto · 2004 · Chemical and Pharmaceutical Bulletin
19. Effects of Membrane Mimetics on Cytochrome P450-Cytochrome b5 Interactions Characterized by NMR Spectroscopy
    Meng Zhang, Rui Huang, Sang‐Choul Im, Lucy A. Waskell, Ayyalusamy Ramamoorthy · 2015 · Journal of Biological Chemistry
20. Computational Solvent Mapping Reveals the Importance of Local Conformational Changes for Broad Substrate Specificity in Mammalian Cytochromes P450
    Karl H. Clodfelter, David J. Waxman, Sándor Vajda · 2006 · Biochemistry
21. Role of the conserved threonine 309 in mechanism of oxidation by cytochrome P450 2D6
    Peter H. J. Keizers, Loek H.M. Schraven, Chris de Graaf, Mats Hidestrand, Magnus Ingelman‐Sundberg, Ben R. van Dijk, Nico P.E. Vermeulen, Jan N. M. Commandeur · 2005 · Biochemical and Biophysical Research Communications
22. Homology modeling of the three membrane proteins of the dhurrin metabolon: Catalytic sites, membrane surface association and protein–protein interactions
    Kenneth Jensen, Sarah A. Osmani, Thomas Hamann, Peter Naur, Birger Lindberg Møller · 2011 · Phytochemistry
23. Genome‐wide association study for feedlot average daily gain in Nellore cattle ( Bos indicus )
    Miguel Henrique de Almeida Santana, Yuri Tani Utsunomiya, Haroldo Henrique de Rezende Neves, Rodrigo da Costa Gomes, José Fernando Garcia, Heidge Fukumasu, Saulo da Luz e Silva, Paulo Roberto Leme, Luiz Lehmann Coutinho, Joanir Pereira Eler et al. · 2014 · Journal of Animal Breeding and Genetics
24. Genome-Wide Identification and Analyses of Drought/Salt-Responsive Cytochrome P450 Genes in Medicago truncatula
    Yaying Xia, Junfeng Yang, Lin Ma, Yan Su, Yongzhen Pang · 2021 · International Journal of Molecular Sciences
25. Molecular Similarity and Xenobiotic Metabolism
    Sam Adams · 2010
26. Expression of human cytochrome P450 46A1 in Escherichia coli: effects of N- and C-terminal modifications
    Natalia Mast, Ulla Andersson, Kazuo Nakayama, Ingemar Björkhem, Irina A. Pikuleva · 2004 · Archives of Biochemistry and Biophysics
27. Understanding CYP2D6 interactions
    Marcel John de Groot, Florian Wakenhut, Gavin A. Whitlock, Ruth Hyland · 2009 · Drug Discovery Today
28. Structural characterization of human cholesterol 7α-hydroxylase
    W. Tempel, Irina P. Grabovec, Farrell MacKenzie, Yaroslav V. Dichenko, Sergey A. Usanov, Andrei A. Gilep, Hee‐Won Park, Natallia V. Strushkevich · 2014 · Journal of Lipid Research
29. Mechanism-Based Inactivation of Cytochromes P450 2E1 and 2E1 T303A by tert-Butyl Acetylenes: Characterization of Reactive Intermediate Adducts to the Heme and Apoprotein
    Anna Louise Blobaum, Ute M. Kent, William L. Alworth, Paul F. Hollenberg · 2002 · Chemical Research in Toxicology
30. Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies
    園子 増田, David E. Prosser, Yu-Ding Guo, Martin Kaufmann, Glenville Jones · 2006 · Archives of Biochemistry and Biophysics
31. Fluorescent Probes for Cytochrome P450 Structural Characterization and Inhibitor Screening
    Alexander R. Dunn, Anna‐Maria A. Hays, David B. Goodin, Charles David Stout, Richard Chiu, Jay R. Winkler, Harry B. Gray · 2002 · Journal of the American Chemical Society
32. Functional role of residues in the helix B′ region of cytochrome P450 2B1
    Wataru Honma, Weihua Li, Hong Shu Liu, Emily E. Scott, James R. Halpert · 2004 · Archives of Biochemistry and Biophysics
33. ALLENE OXIDE SYNTHASE and HYDROPEROXIDE LYASE, Two Non-Canonical Cytochrome P450s in Arabidopsis thaliana and Their Different Roles in Plant Defense
    Sachin Rustgi, Armin Springer, ChulHee Kang, Diter von WETTSTEIN, Christiane Reinbothe, Steffen Reinbothe, Stephan Pollmann · 2019 · International Journal of Molecular Sciences
34. THE 2002 BERNARD B. BRODIE AWARD LECTURE
    Eric F. Johnson · 2003 · Drug Metabolism and Disposition
35. High-throughput x-ray crystallography for structure-based drug design
    Kenneth E. Goodwill, Michael G. Tennant, Raymond C. Stevens · 2001 · Drug Discovery Today
36. Selective Inhibition of Dog Hepatic CYP2B11 and CYP3A12
    Ping Lü, Suresh B. Singh, Brian Carr, Yulin Fang, Cathie Dong Xiang, Thomas H. Rushmore, A. David Rodrigues, Magang Shou · 2005 · Journal of Pharmacology and Experimental Therapeutics
37. Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket.
    Kazuto Ohkura, Yuki Kawaguchi, Yasuko Watanabe, Yasuhiro Masubuchi, Yasuo Shinohara, Hitoshi Hori · 2009 · PubMed
38. Amino Acid Residues Critical for Differential Inhibition of CYP2B4, CYP2B5, and CYP2B1 by Phenylimidazoles
    Margit Spatzenegger, Qinmi Wang, You He, Michael R. Wester, Eric F. Johnson, James R. Halpert · 2001 · Molecular Pharmacology
39. Mechanism-based Inhibition Profiles of Erythromycin and Clarithromycin with Cytochrome P450 3A4 Genetic Variants
    Takeshi Akiyoshi, Marie Ito, Saori Murase, Mitsue Miyazaki, Frederick Peter Guengerich, Katsunori Nakamura, Koujirou Yamamoto, Hisakazu Ohtani · 2013 · Drug Metabolism and Pharmacokinetics
40. QSAR of cytochrome inhibitors
    Kunal Roy, Partha Pratim Roy · 2009 · Expert Opinion on Drug Metabolism & Toxicology
41. The Catalytic Mechanism of Steroidogenic Cytochromes P450 from All-Atom Simulations: Entwinement with Membrane Environment, Redox Partners, and Post-Transcriptional Regulation
    Angelo Spinello, Ida Ritacco, Alessandra Magistrato · 2019 · Catalysts
42. Multiple molecular recognition mechanisms. Cytochrome P450—A case study
    Rebecca C. Wade, Domantas Motiejunas, Karin Schleinkofer, sudarko sudarko, Peter J. Winn, Amit Banerjee, Andrei Kariakin, Christiane Jung · 2005 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
43. Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis
    Benjamin C. Lewis, Peter I. Mackenzie, John O. Miners · 2007 · Archives of Biochemistry and Biophysics
44. Solution structure and topology of the N-terminal membrane anchor domain of a microsomal cytochrome P450: prostaglandin I2 synthase
    Ke‐He Ruan, Shui‐Ping So, Weida Zheng, Jiaxin Wu, Dawei Li, Jennifer KUNG · 2002 · Biochemical Journal
45. MECHANISM-BASED INACTIVATION AND REVERSIBILITY: IS THERE A NEW TREND IN THE INACTIVATION OF CYTOCHROME P450 ENZYMES?
    Anna Louise Blobaum · 2005 · Drug Metabolism and Disposition
46. Conformational Mobility in Cytochrome P450 3A4 Explored by Pressure-Perturbation EPR Spectroscopy
    Dmitri R. Davydov, Zhongyu Yang, Nadezhda Y. Davydova, James R. Halpert, Wayne L. Hubbell · 2016 · Biophysical Journal
47. Watermelon (Citrullus lanatus) Hydroperoxide Lyase Greatly Increases C6Aldehyde Formation in Transgenic Leaves
    Hirotada Fukushige, David F. Hildebrand · 2005 · Journal of Agricultural and Food Chemistry
48. Mechanistic Basis of Electron Transfer to Cytochromes P450 by Natural Redox Partners and Artificial Donor Constructs
    Peter Hlavica · 2015 · Advances in experimental medicine and biology
49. Effect of Cholesterol on the Structure of Membrane-Attached Cytochrome P450 3A4
    Veronika Navrátilová, Markéta Paloncýová, Michaela Kajšová, Karel Berka, Michal Otyepka · 2015 · Journal of Chemical Information and Modeling
50. Extending the capabilities of nature’s most versatile catalysts: Directed evolution of mammalian xenobiotic-metabolizing P450s
    Elizabeth M. J. Gillam · 2007 · Archives of Biochemistry and Biophysics
51. Structure and Function of Cytochromes P450 2B: From Mechanism-Based Inactivators to X-Ray Crystal Structures and Back
    James R. Halpert · 2011 · Drug Metabolism and Disposition
52. Impact of six fruits—banana, guava, mangosteen, pineapple, ripe mango and ripe papaya—on murine hepatic cytochrome P450 activities
    Waranya Chatuphonprasert, Kanokwan Jarukamjorn · 2012 · Journal of Applied Toxicology
53. Glucuronides as Potential Anionic Substrates of Human Cytochrome P450 2C8 (CYP2C8)
    Yong Ma, Yue Fu, Siamak Cyrus Khojasteh, Deepak Dalvie, Donglu Zhang · 2017 · Journal of Medicinal Chemistry
54. The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners
    Francisco Esteves, Diana Campelo, Bruno Costa Gomes, Philippe Urban, Sophie Bozonnet, Thomas Lautier, José Rueff, Gilles Truan, Michel Kranendonk · 2020 · Frontiers in Pharmacology
55. Purification and crystallization of N-terminally truncated forms of microsomal cytochrome P450 2C5
    Michael R. Wester, Charles David Stout, Eric F. Johnson · 2002 · Methods in enzymology on CD-ROM/Methods in enzymology
56. Molecular modeling of mammalian cytochrome P450s
    R. Dai, Matthew R. Pincus, Fred K. Friedman · 2000 · Cellular and Molecular Life Sciences
57. Designing and Creating a Synthetic Omega Oxidation Pathway in Saccharomyces cerevisiae Enables Production of Medium-Chain α, ω-Dicarboxylic Acids
    Li Han, Yanfeng Peng, Yuangyuan Zhang, Wujiu Chen, Yuping Lin, Qinhong Wang · 2017 · Frontiers in Microbiology
58. A NEW CLASS OF CYP2C9 INHIBITORS: PROBING 2C9 SPECIFICITY WITH HIGH-AFFINITY BENZBROMARONE DERIVATIVES
    Charles W. Locuson, Jan L. Wahlstrom, Denise A. Rock, Dan A. Rock, Jeffrey P. Jones · 2003 · Drug Metabolism and Disposition
59. From structure and functions of steroidogenic enzymes to new technologies of gene engineering
    Ludmila A. Novikova, Yaroslav V. Faletrov, Irina E. Kovaleva, Stephan Mauersberger, Valentin N. Luzikov, V. M. Shkumatov · 2009 · Biochemistry (Moscow)
60. Physical Studies of P450–P450 Interactions: Predicting Quaternary Structures of P450 Complexes in Membranes from Their X-ray Crystal Structures
    James Robert Reed, Wayne L. Backes · 2017 · Frontiers in Pharmacology
61. New findings in studies of cytochromes P450
    Ksenia N. Myasoedova · 2008 · Biochemistry (Moscow)
62. Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: Insights into substrate specificity and membrane bound structure–function
    Andrew J. Annalora, Ekaterina Bobrovnikov-Marjon, Rita Elena Serda, Andrzej Pastuszyn, Sandra E. Graham, Craig B. Marcus, John L. Omdahl · 2006 · Archives of Biochemistry and Biophysics
63. Three Novel <i>CYP11B1</i> Mutations in Congenital Adrenal Hyperplasia due to Steroid 11Beta-Hydroxylase Deficiency in a Moroccan Population
    Chabraoui, L., Abid, F., Menassa, R., Gaouzi, A., El Hessni, A., Morel, Y. · 2010 · Hormone Research in Paediatrics
64. The challenges of in silico contributions to drug metabolism in lead optimization
    Roy J. Vaz, Ismael Zamora, Yi Li, Stephan Reiling, Jian Shen, Gabriele Cruciani · 2010 · Expert Opinion on Drug Metabolism & Toxicology
65. Identification of 17-α-Ethynylestradiol-Modified Active Site Peptides and Glutathione Conjugates Formed during Metabolism and Inactivation of P450s 2B1 and 2B6
    Ute M. Kent, Hsia-lien Lin, Danielle E. Mills, Kelly A. Regal, Paul F. Hollenberg · 2006 · Chemical Research in Toxicology
66. Role of conserved Asp293 of cytochrome P450 2C9 in substrate recognition and catalytic activity
    Jack U. Flanagan, Lesley A. McLaughlin, Mark J. I. Paine, Michael J. Sutcliffe, Gordon C. K. Roberts, C. Roland Wolf · 2003 · Biochemical Journal
67. The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins
    Tammy L. Domanski, You-Qun He, Emily E. Scott, Qinmi Wang, James R. Halpert · 2001 · Archives of Biochemistry and Biophysics
68. The Effect of Force-Field Parameters on Cytochrome P450-Membrane Interactions: Structure and Dynamics
    Ghulam Mustafa, Prajwal Prabhakarrao Nandekar, Goutam Mukherjee, Neil J. Bruce, Rebecca C. Wade · 2020 · Scientific Reports
69. Dioxin impacts on lipid metabolism of soil microbes: towards effective detection and bioassessment strategies
    Sabrin Mahfouz, Ghaytha Mansour, Denis J. Murphy, Abdulsamie Hanano · 2020 · Bioresources and Bioprocessing
70. Molecular Dynamics Simulation Framework to Probe the Binding Hypothesis of CYP3A4 Inhibitors
    Yusra Sajid Kiani, Kara E. Ranaghan, Ishrat Jabeen, Adrian John Mulholland · 2019 · International Journal of Molecular Sciences
71. Orientation of Caffeine within the Active Site of Human Cytochrome P450 1A2 Based on NMR Longitudinal (T1) Relaxation Measurements
    Kelly A. Regal, Sidney D. Nelson · 2000 · Archives of Biochemistry and Biophysics
72. Species differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactions
    D. F. V. Lewis, Brian G. Lake · 2002 · Xenobiotica
73. Apo-cytochrome b5 as an indicator of changes in heme accessability:
    Andrei A. Gilep, Oleg L. Guryev, Sergey A. Usanov, Ronald W. Estabrook · 2001 · Journal of Inorganic Biochemistry
74. Why human cytochrome P450c21 is a progesterone 21-hydroxylase
    Mizrachi, Dario, Wang, Zhu, Sharma, Kamalesh K., Gupta, Manisha K., Xu, Keliang, Dwyer, Christopher R., Auchus, Richard J. · 2011 · Biochemistry
75. Elucidating Substrate Promiscuity in the Human Cytochrome 3A4
    Christina Hayes, Daniel Ansbro, Maria Kontoyianni · 2014 · Journal of Chemical Information and Modeling
76. Evaluation of the binding orientations of testosterone in the active site of homology models for CYP2C11 and CYP2C13
    Hongwu Wang, Jemmie Cheng, Diana L. Montgomery, K.-C. Cheng · 2009 · Biochemical Pharmacology
77. Characterization of Cytochrome P450 Enzymes and Their Applications in Synthetic Biology
    Laura N. Jeffreys, Hazel M. Girvan, Kirsty J. McLean, Andrew W. Munro · 2018 · Methods in enzymology on CD-ROM/Methods in enzymology
78. Anticancer Activity of Samarium-Coated Magnesium Implants for Immunocompromised Patients
    Kannan Saranya, Nallaiyan Rajendran · 2020 · ACS Applied Bio Materials
79. The Diversity and Importance of Microbial Cytochromes P450
    Steven L. Kelly, Diane E Kelly, Colin J. Jackson, Andrew G. S. Warrilow, David C. Lamb · 2007 · Springer eBooks
80. Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure
    D. F. V. Lewis, Brian G. Lake, Maurice Dickins, Yune‐Fang Ueng, Peter S. Goldfarb · 2003 · Xenobiotica
81. Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity
    D. F. V. Lewis, Yuko Ito · 2009 · Xenobiotica
82. Samarium enriches antitumor activity of ZnO nanoparticles via downregulation of CXCR4 receptor and cytochrome P450
    Asmaa I. Nabeel · 2020 · Tumor Biology
83. Molecular Modeling on Inhibitor Complexes and Active-Site Dynamics of Cytochrome P450 C17, a Target for Prostate Cancer Therapy
    Shozeb M Haider, Jagdish Suresh Patel, Chetan Poojari, Stephen Neidle · 2010 · Journal of Molecular Biology
84. The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system
    Su‐Jun Lee, L. Perera, Sherry J. Coulter, Harvey W. Mohrenweiser, Anton M. Jetten, Joyce A. Goldstein · 2007 · Pharmacogenetics and Genomics
85. Classification and characterization of putative cytochrome P450 genes from Panax ginseng C. A. Meyer
    Balusamy Sri Renuka Devi, Yu-Jin Kim, Subramaniyum Sathiyamoorthy, Altanzul Khorolragchaa, Sathiyaraj Gayathri, Shohana Parvin, Dong‐Uk Yang, Senthil Kalai Selvi, Ok Ran Lee, Sungyoung Lee et al. · 2011 · Biochemistry (Moscow)
86. Homology modeling of human 25-hydroxyvitamin D3 1α-hydroxylase (CYP27B1) based on the crystal structure of rabbit CYP2C5
    Keiko Yamamoto, Hiroyuki Masuno, Natsumi Sawada, Toshiyuki Sakaki, Kuniyo Inouye, Masaji Ishiguro, Sachiko Yamada · 2004 · The Journal of Steroid Biochemistry and Molecular Biology
87. Stereospecific Deuterium Substitution Attenuates the Tumorigenicity and Metabolism of the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
    John R. Jalas, Edward J. McIntee, Patrick M. J. Kenney, Pramod Upadhyaya, Lisa A. Peterson, Stephen S. Hecht · 2003 · Chemical Research in Toxicology
88. Le métabolisme des xénobiotiques : effets bénéfiques, effets néfastes
    Daniel Mansuy · 2013 · Biologie Aujourd hui
89. Mutagenesis and molecular dynamics suggest structural and functional roles for residues in the N-terminal portion of the cytochrome P450 2B1 I helix
    Emily E. Scott, Hong Liu, You He, Weihua Li, James R. Halpert · 2004 · Archives of Biochemistry and Biophysics
90. Putative F–G loop is involved in association with the membrane in P450scc (P450 11A1)
    Irina A. Pikuleva · 2004 · Molecular and Cellular Endocrinology
91. Thermodynamic Fidelity of the Mammalian Cytochrome P450 2B4 Active Site in Binding Substrates and Inhibitors
    Bilikallahalli K. Muralidhara, Ling Sun, Surendra S. Negi, James R. Halpert · 2008 · Journal of Molecular Biology
92. Polymorphisms of CYP51A1 from Cholesterol Synthesis: Associations with Birth Weight and Maternal Lipid Levels and Impact on CYP51 Protein Structure
    Monika Lewińska, Urška Zelenko, Franci Merzel, Simona Golič Grdadolnik, Jeffrey Clark Murray, Damjana Rozman · 2013 · PLoS ONE
93. Change in enantioselectivity in bufuralol 1?-hydroxylation by the substitution of phenylalanine-120 by alanine in cytochrome P450 2D6
    Kazufumi Masuda, Keietsu Tamagake, Yukie Okuda, Fumihiro Torigoe, Daisuke Tsuzuki, Takashi Isobe, Hiroyuki Hichiya, Nobumitsu Hanioka, Shigeo Yamamoto, Shizuo Narimatsu · 2004 · Chirality
94. Catalytic roles of CYP2D6.10 and CYP2D6.36 enzymes in mexiletine metabolism: In vitro functional analysis of recombinant proteins expressed in Saccharomyces cerevisiae
    Nobumitsu Hanioka, Yoshihito Okumura, Yoshiro Saito, Hiroyuki Hichiya, Akiko Soyama, Keita Saito, Kazuyuki Ueno, Jun-ichi Sawada, Shizuo Narimatsu · 2006 · Biochemical Pharmacology
95. Defining Targets for Investigating the Pharmacogenomics of Adverse Drug Reactions to Antifungal Agents
    Joseph Meletiadis, Stephen Jacob Chanock, Thomas J. Walsh · 2008 · Pharmacogenomics
96. SINGLE NUCLEOTIDE POLYMORPHISMS OF THE HUMAN CYP2A13 GENE: EVIDENCE FOR A NULL ALLELE
    Xiuling Zhang, Ying Chen, Yiqin Liu, Xiang Shan Ren, Qing-Yu Zhang, Michele Caggana, Xinxin Ding · 2003 · Drug Metabolism and Disposition
97. The planetary biology of cytochrome P450 aromatases
    Eric A. Gaucher, Logan G Graddy, Tang Li, Rosalia C.M. Simmen, Frank A. Simmen, David Schreiber, David A. Liberles, Christine M. Janis, Steven A. Benner · 2004 · BMC Biology
98. Functional evaluation of cytochrome P450 2D6 with Gly42Arg substitution expressed in Saccharomyces cerevisiae
    Daisuke Tsuzuki, Chie Takemi, Shigeo Yamamoto, Keietsu Tamagake, Susumu Imaoka, Yoshihiko Funae, Hiroyuki Kataoka, Sumió Shinoda, Shizuo Narimatsu · 2001 · Pharmacogenetics
99. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
    Eric F. Johnson, John Patrick Connick, James Robert Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence, Emily E. Scott · 2013 · Drug Metabolism and Disposition
100. Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences
     Dmitri R. Davydov, Nadezhda Y. Davydova, John T. Rodgers, Thomas H. Rushmore, Jeffrey P. Jones · 2017 · Biochemical Journal