The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
PDMAEMA based gene delivery materials
Open accessAbstract
Gene transfection is the transfer of genetic material like DNA into cells. Cationic polymers which form nanocomplexes with DNA, so-called non-viral gene vectors, are a highly promising platform for efficient gene transfection. Despite intensive research efforts and some of the on-going clinical trials on gene transfection, none of the existing cationic polymer systems are generally acceptable for human gene therapy. Since the process of gene transfection is complex and puts different challenges and demands on the delivery system, there is a strong requirement for the design and development of a multifunctional system in a simple way. This review will discuss recent efforts in design, synthesis, and performance of poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) nanocomplexes with DNA.
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Cited by
Karimi, M., Sahandi Zangabad, P., Ghasemi, A., Amiri, M., Bahrami, M., Malekzad, H., Ghahramanzadeh Asl, H., Mahdieh, Z., Bozorgomid, M., Ghasemi, A., et al. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b00371 · Cited by 500
Recent progress in biomedical applications of pluronic (PF127): Pharmaceutical perspectives
Akash, M. S. H., & Rehman, K. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.04.032 · Cited by 394
Polymeric Delivery of Therapeutic Nucleic Acids
Kumar, R., Santa Chalarca, C. F., Bockman, M. R., Bruggen, C. V., Grimme, C. J., Dalal, R. J., Hanson, M. G., Hexum, J. K., & Reineke, T. M. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00997 · Cited by 365
Hyaluronic acid and albumin based nanoparticles for drug delivery
Lei, C., Liu, X.-R., Chen, Q.-B., Li, Y., Zhou, J.-L., Zhou, L.-Y., & Zou, T. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.01.033 · Cited by 266
pH-Responsive PDMS- b -PDMAEMA Micelles for Intracellular Anticancer Drug Delivery
Car, A., Baumann, P., Duskey, J. T., Chami, M., Bruns, N., & Meier, W. (2014) · Biomacromolecules · doi:10.1021/bm500919z · Cited by 113
Metadata
- Authors
- Agarwal, S., Zhang, Y., Maji, S., & Greiner, A.
- Venue
- Materials Today
- Publisher
- Elsevier BV
- Published
- 2012-09
- Volume
- 15
- Issue
- 9
- Pages
- 388-393
- ISSN
- 1369-7021 (ISSN-L)
- OpenAlex
- W2067923079
- Cited by
- 342
- References
- 51
- FWCI
- 5.34
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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