The DOI matches its Crossref record; 41 of the 42 references it cites were found in a registry or an index.
Bone tissue engineering: from bench to bedside
Open accessAbstract
The drive to develop bone grafts for the filling of major gaps in the skeletal structure has led to a major research thrust towards developing biomaterials for bone engineering. Unfortunately, from a clinical perspective, the promise of bone tissue engineering which was so vibrant a decade ago has so far failed to deliver the anticipated results of becoming a routine therapeutic application in reconstructive surgery. Here we describe our bench to bedside concept, the first clinical results and a detailed analysis of long-term bone regeneration studies in preclinical animal models, exploiting methods of micro- and nano analysis of biodegradable composite scaffolds.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Langer, R., & Vacanti, J. P. (1993) · Science · doi:10.1126/science.8493529 · Cited by 9,893
Scaffolds in tissue engineering bone and cartilage
Hutmacher, D. W. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00121-6 · Cited by 5,061
Self-citationThe return of a forgotten polymer—Polycaprolactone in the 21st century
Woodruff, M. A., & Hutmacher, D. W. (2010) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2010.04.002 · Cited by 4,033
Self-citationGrowth Factors, Matrices, and Forces Combine and Control Stem Cells
Discher, D. E., Mooney, D. J., & Zandstra, P. W. (2009) · Science · doi:10.1126/science.1171643 · Cited by 2,666
Tissue Engineering--Current Challenges and Expanding Opportunities
Griffith, L. G., & Naughton, G. K. (2002) · Science · doi:10.1126/science.1069210 · Cited by 2,348
Fused deposition modeling of novel scaffold architectures for tissue engineering applications
Zein, I., Hutmacher, D. W., Tan, K. C., & Teoh, S. H. (2002) · Biomaterials · doi:10.1016/s0142-9612(01)00232-0 · Cited by 1,874
Self-citationGee, G. (1972) · Polymer · doi:10.1016/0032-3861(72)90025-0 · Cited by 1,367
Animal models for implant biomaterial research in bone: A review
AO Research Institute, A. F., Pearce, A., Richards, R., Milz, S., Schneider, E., & Pearce, S. (2007) · European Cells and Materials · doi:10.22203/ecm.v013a01 · Cited by 1,289
Additive manufacturing of tissues and organs
Melchels, F. P. W., Domingos, M. A. N., Klein, T. J., Malda, J., Bártolo, P., & Hutmacher, D. W. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.11.007 · Cited by 1,223
Self-citationHutmacher, D. W., Schantz, J. T., Lam, C. X. F., Tan, K. C., & Lim, T. C. (2007) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.24 · Cited by 1,007
Self-citation
Research works printed but not linked: 4
- Schantz, 2003, Mary Ann Liebert Inc Publ, S127
- Schantz, 2003, Mary Ann Liebert Inc Publ, S113
- Berner, 2011, Cells and Tissue Research
- Abbah, 2008, Mary Ann Liebert Inc, OP3
Cited by
Sorted by citations
Materials design for bone-tissue engineering
Koons, G. L., Diba, M., & Mikos, A. G. (2020) · Nature Reviews Materials · doi:10.1038/s41578-020-0204-2 · Cited by 1,769
Bone Regeneration Based on Tissue Engineering Conceptions — A 21st Century Perspective
Henkel, J., Woodruff, M. A., Epari, D. R., Steck, R., Glatt, V., Dickinson, I. C., Choong, P., Schuetz, M., & Hutmacher, D. W. (2013) · Bone Research · doi:10.4248/br201303002 · Cited by 910
Self-citationHierarchical Structures of Bone and Bioinspired Bone Tissue Engineering
Liu, Y., Luo, D., & Wang, T. (2016) · Small · doi:10.1002/smll.201600626 · Cited by 482
Hierarchically designed bone scaffolds: From internal cues to external stimuli
Du, Y., Guo, J. L., Wang, J., Mikos, A. G., & Zhang, S. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119334 · Cited by 253
Melt Electrospinning and Its Technologization in Tissue Engineering
Muerza-Cascante, M. L., Haylock, D. N., Hutmacher, D. W., & Dalton, P. D. (2014) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2014.0347 · Cited by 215
Self-citation
Metadata
- Authors
- Woodruff, M. A., Lange, C., Reichert, J., Berner, A., Chen, F., Fratzl, P., Schantz, J.-T., & Hutmacher, D. W.
- Affiliations
- Queensland University of Technology (AU)
- Max Planck Society (DE)
- University of Würzburg (DE)
- University of Regensburg (DE)
- Air Force Medical University (CN)
- TUM Klinikum (DE)
- Georgia Institute of Technology (US)
- Corresponding author
- Hutmacher, Dietmar W.
- Venue
- Materials Today
- Publisher
- Elsevier BV
- Published
- 2012-10
- Volume
- 15
- Issue
- 10
- Pages
- 430-435
- ISSN
- 1369-7021 (ISSN-L)
- OpenAlex
- W2089789987
- Cited by
- 182
- References
- 42
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 11 · 2023: 12 · 2022: 14 · 2021: 17 · 2020: 20 · 2019: 12 · 2018: 11 · 2017: 23 · 2016: 15 · 2015: 9 · 2014: 12 · 2013: 10
- FWCI
- 5.65
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Materials Today (publishedVersion, cc-by-nc-nd)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion, other-oa)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Keywords
- bone tissue engineering, bone grafting, biomaterials, bone regeneration, preclinical animal models, clinical translation, reconstructive surgery
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
