Cited by 221Oral Health Pathology and TreatmentHead and Neck Cancer StudiesGlobal Public Health Policies and Epidemiology

Defining a global research and policy agenda for betel quid and areca nut

Mehrtash, Hedieh, Duncan, Kalina, Parascandola, Mark, David, Annette, Gritz, Ellen R, Gupta, Prakash C, Mehrotra, Ravi, Amer Nordin, Amer Siddiq +5 more·2017·The Lancet Oncology

Abstract

Betel quid and areca nut are known risk factors for many oral and oesophageal cancers, and their use is highly prevalent in the Asia-Pacific region. Additionally, betel quid and areca nut are associated with health effects on the cardiovascular, nervous, gastrointestinal, metabolic, respiratory, and reproductive systems. Unlike tobacco, for which the WHO Framework Convention on Tobacco Control provides evidence-based policies for reducing tobacco use, no global policy exists for the control of betel quid and areca nut use. Multidisciplinary research is needed to address this neglected global public health emergency and to mobilise efforts to control betel quid and areca nut use. In addition, future research is needed to advance our understanding of the basic biology, mechanisms, and epidemiology of betel quid and areca nut use, to advance possible prevention and cessation programmes for betel quid and areca nut users, and to design evidence-based screening and early diagnosis programmes to address the growing burden of cancers that are associated with use.

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Crossref · 10.1016/s1470-2045(17)30460-6

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70 of 70 references verified0 citation errors · 0 not checkable

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  • Major risk factors for oral cancers are tobacco, alcohol and areca nut.

    “The major risk factors for oral cancers are tobacco, alcohol and areca nut (betel quid).[25][26][27]”

    From Oral diseases: a global public health challenge (2019) · cites this paper as [27]

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Authors
Mehrtash, H., Duncan, K., Parascandola, M., David, A., Gritz, E. R., Gupta, P. C., Mehrotra, R., Amer Nordin, A. S., Pearlman, P. C., Warnakulasuriya, S., Wen, C.-P., Zain, R. B., & Trimble, E. L.
Affiliations
  • National Institutes of Health (US)
  • The University of Texas MD Anderson Cancer Center (US)
  • Healis Sekhsaria Institute For Public Health (IN)
  • National Institute of Cancer Prevention and Research (IN)
  • King's College London (GB)
  • National Health Research Institutes (TW)
  • University of Malaya (MY)
Corresponding author
Mehrtash, Hedieh
Venue
The Lancet Oncology
Publisher
Elsevier BV
Published
2017-12
Volume
18
Issue
12
Pages
e767-e775
ISSN
1470-2045 (ISSN-L)
OpenAlex
W2773997905
Cited by
221
References
71
Citations by year
2026: 20 · 2025: 27 · 2024: 22 · 2023: 27 · 2022: 43 · 2021: 22 · 2020: 39 · 2019: 13 · 2018: 7
FWCI
2.26
Type
journal article
Language
en
Open access
closed
Locations
  • The Lancet Oncology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Dentistry › Periodontics › Oral Health Pathology and Treatment
  • Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
  • Social Sciences › Business, Management and Accounting › Organizational Behavior and Human Resource Management › Global Public Health Policies and Epidemiology
Keywords
betel quid, areca nut, oral cancer, esophageal cancer, oral submucous fibrosis, oral leukoplakia, oral cancer screening, early diagnosis, prevention programmes, health policy, Asia-Pacific region, tobacco control
MeSH terms
Areca, Asia, Esophageal Neoplasms, Female, Humans, Male, Mouth Neoplasms, Policy Making, Research Design, Smoking, Global Health, Practice Guidelines as Topic, Early Detection of Cancer

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