The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Confronting the avian influenza threat: vaccine development for a potential pandemic
Open accessAbstract
Summary Sporadic human infection with avian influenza viruses has raised concern that reassortment between human and avian subtypes could generate viruses of pandemic potential. Vaccination is the principal means to combat the impact of influenza. During an influenza pandemic the immune status of the population would differ from that which exists during interpandemic periods. An emerging pandemic virus will create a surge in worldwide vaccine demand and new approaches in immunisation strategies may be needed to ensure optimum protection of unprimed individuals when vaccine antigen may be limited. The manufacture of vaccines from pathogenic avian influenza viruses by traditional methods is not feasible for safety reasons as well as technical issues. Strategies adopted to overcome these issues include the use of reverse genetic systems to generate reassortant strains, the use of baculovirusexpressed haemagglutinin or related non-pathogenic avian influenza strains, and the use of adjuvants to enhance immunogenicity. In clinical trials, conventional surfaceantigen influenza virus vaccines produced from avian viruses have proved poorly immunogenic in immunologically naive populations. Adjuvanted or whole-virus preparations may improve immunogenicity and allow sparing of antigen.
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Belshe, R. B., Mendelman, P. M., Treanor, J., King, J., Gruber, W. C., Piedra, P., Bernstein, D. I., Hayden, F. G., Kotloff, K., Zangwill, K., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199805143382002 · Cited by 916
Cheung, C., Poon, L., Lau, A., Luk, W., Lau, Y., Shortridge, K., Gordon, S., Guan, Y., & Peiris, J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11772-7 · Cited by 889
Re-emergence of fatal human influenza A subtype H5N1 disease
Peiris, J., Yu, W., Leung, C., Cheung, C., Ng, W., Nicholls, J., Ng, T., Chan, K., Lai, S., Lim, W., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)15595-5 · Cited by 812
Origin and evolution of the 1918 “Spanish” influenza virus hemagglutinin gene
Reid, A. H., Fanning, T. G., Hultin, J. V., & Taubenberger, J. K. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.4.1651 · Cited by 607
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Cellular immune correlates of protection against symptomatic pandemic influenza
Sridhar, S., Begom, S., Bermingham, A., Hoschler, K., Adamson, W., Carman, W., Bean, T., Barclay, W., Deeks, J. J., & Lalvani, A. (2013) · Nature Medicine · doi:10.1038/nm.3350 · Cited by 862
Influenza: lessons from past pandemics, warnings from current incidents
Horimoto, T., & Kawaoka, Y. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1208 · Cited by 696
Murray, C. J., Lopez, A. D., Chin, B., Feehan, D., & Hill, K. H. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69895-4 · Cited by 605
Quan, F.-S., Huang, C., Compans, R. W., & Kang, S.-M. (2007) · Journal of Virology · doi:10.1128/jvi.02052-06 · Cited by 313
Stephenson, I., Bugarini, R., Nicholson, K. G., Podda, A., Wood, J. M., Zambon, M. C., & Katz, J. M. (2005) · The Journal of Infectious Diseases · doi:10.1086/428948 · Cited by 285
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Metadata
- Authors
- Stephenson, I., Nicholson, K. G., Wood, J. M., Zambon, M. C., & Katz, J. M.
- Venue
- The Lancet Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2004-08
- Volume
- 4
- Issue
- 8
- Pages
- 499-509
- ISSN
- 1473-3099 (ISSN-L)
- OpenAlex
- W2107487305
- Cited by
- 173
- References
- 4
- FWCI
- 15.31
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Stephenson, I., Nicholson, K. G., Wood, J. M., Zambon, M. C., & Katz, J. M. (2004). Confronting the avian influenza threat: vaccine development for a potential pandemic. The Lancet Infectious Diseases. https://doi.org/10.1016/s1473-3099(04)01105-3
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
