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Cited by 2,410

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances

Open access
Volpe, Joseph J·2009·The Lancet Neurology

Abstract

Brain injury in premature infants is of enormous public health importance because of the large number of such infants who survive with serious neurodevelopmental disability, including major cognitive deficits and motor disability. This type of brain injury is generally thought to consist primarily of periventricular leukomalacia (PVL), a distinctive form of cerebral white matter injury. Important new work shows that PVL is frequently accompanied by neuronal/axonal disease, affecting the cerebral white matter, thalamus, basal ganglia, cerebral cortex, brain stem, and cerebellum. This constellation of PVL and neuronal/axonal disease is sufficiently distinctive to be termed “encephalopathy of prematurity”. The thesis of this Review is that the encephalopathy of prematurity is a complex amalgam of primary destructive disease and secondary maturational and trophic disturbances. This Review integrates the fascinating confluence of new insights into both brain injury and brain development during the human premature period.

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Crossref · 10.1016/s1474-4422(08)70294-1

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Metadata

Authors
Volpe, J. J.
Venue
The Lancet Neurology
Publisher
Elsevier BV
Published
2009-01
Volume
8
Issue
1
Pages
110-124
ISSN
1474-4422 (ISSN-L)
OpenAlex
W2158698668
Cited by
2,410
References
15
FWCI
62.80
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. https://app.cochat.ai/papers/10.1016/s1474-4422(08)70294-1
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Volpe, J. J. (2009). Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. The Lancet Neurology. https://doi.org/10.1016/s1474-4422(08)70294-1

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.