The DOI matches its Crossref record; 73 of the 74 references it cites were found in a registry or an index.
Functional (psychogenic) movement disorders: merging mind and brain
Abstract
Functional (psychogenic) movement disorders (FMD) are part of the wide spectrum of functional neurological disorders, which together account for over 16% of patients referred to neurology clinics. FMD have been described as a "crisis for neurology" and cause major challenges in terms of diagnosis and treatment. As with other functional disorders, a key issue is the absence of pathophysiological understanding. There has been an influential historical emphasis on causation by emotional trauma, which is not supported by epidemiological studies. The similarity between physical signs in functional disorders and those that occur in feigned illness has also raised important challenges for pathophysiological understanding and has challenged health professionals' attitudes toward patients with these disorders. However, physical signs and selected investigations can help clinicians to reach a positive diagnosis, and modern pathophysiological research is showing an appreciation of the importance of both physical and psychological factors in FMD.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Citations
Cites
Human volition: towards a neuroscience of will
Haggard, P. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2497 · Cited by 1,134
Who is referred to neurology clinics?—The diagnoses made in 3781 new patients
Stone, J., Carson, A. J., Duncan, R., Roberts, R., Warlow, C., Hibberd, C., Coleman, R. J., Cull, R. E., Murray, G. D., Pelosi, A. J., et al. (2010) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2010.05.011 · Cited by 538
Psychological Mechanisms of Medically Unexplained Symptoms: An Integrative Conceptual Model.
Brown, R. J. (2004) · Psychological Bulletin · doi:10.1037/0033-2909.130.5.793 · Cited by 498
Psychogenic movement disorders
Gupta, A., & Lang, A. E. (2009) · Current Opinion in Neurology · doi:10.1097/wco.0b013e32832dc169 · Cited by 440
How many patients with psychogenic nonepileptic seizures also have epilepsy?
Benbadis, S. R., Agrawal, V. K., & Tatum, W. O. (2001) · Neurology · doi:10.1212/wnl.57.5.915 · Cited by 365
Emotional stimuli and motor conversion disorder
Voon, V., Brezing, C., Gallea, C., Ameli, R., Roelofs, K., LaFrance, W. C., & Hallett, M. (2010) · Brain · doi:10.1093/brain/awq054 · Cited by 353
The syndrome of fixed dystonia: an evaluation of 103 patients
Schrag, A. E., Trimble, M., Quinn, N. P., & Bhatia, K. P. (2004) · Brain · doi:10.1093/brain/awh262 · Cited by 351
Self-citationWhat should we say to patients with symptoms unexplained by disease? The “number needed to offend”
Stone, J., Wojcik, W., Durrance, D., Carson, A., Lewis, S. C., MacKenzie, L., Warlow, C. P., & Sharpe, M. (2002) · BMJ · doi:10.1136/bmj.325.7378.1449 · Cited by 336
The involuntary nature of conversion disorder
Voon, V., Gallea, C., Hattori, N., Bruno, M., Ekanayake, V., & Hallett, M. (2010) · Neurology · doi:10.1212/wnl.0b013e3181ca00e9 · Cited by 335
Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons
Ginsberg, S. D., Hemby, S. E., Lee, V. M. ‐., Eberwine, J. H., & Trojanowski, J. Q. (2000) · Annals of Neurology · doi:10.1002/1531-8249(200007)48:1 · Cited by 315
Psychogenic movement disorders: frequency, clinical profile, and characteristics.
Factor, S. A., Podskalny, G. D., & Molho, E. (1995) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.59.4.406 · Cited by 313
Intrathecal Baclofen for the Treatment of Dystonia in Patients with Reflex Sympathetic Dystrophy
van Hilten, B. J., van de Beek, W. T., Hoff, J. I., Voormolen, J. H. C., & Delhaas, E. M. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008313430905 · Cited by 300
Diagnostic and pathophysiological aspects of psychogenic tremors
Deuschl, G., Köster, B., Lücking, C. H., & Scheidt, C. E. (1998) · Movement Disorders · doi:10.1002/mds.870130216 · Cited by 283
The symptom of functional weakness: a controlled study of 107 patients
Stone, J., Warlow, C. P., & Sharpe, M. (2010) · Brain · doi:10.1093/brain/awq068 · Cited by 273
Carson, A. J., Stone, J., Hibberd, C., Murray, G. D., Duncan, R., Coleman, R. J., Warlow, C., ROBERTS, R. C., Pelosi, A. J., Cavanagh, J., et al. (2011) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2010.220640 · Cited by 273
Phenomenology and psychopathology related to psychogenic movement disorders.
Williams, D. T., Ford, B., & Fahn, S. (1995) · PubMed · Cited by 243
Voon, V., Brezing, C., Gallea, C., & Hallett, M. (2011) · Movement Disorders · doi:10.1002/mds.23890 · Cited by 237
Guided self-help for functional (psychogenic) symptoms
Sharpe, M., Walker, J., Williams, C. M., Stone, J., Cavanagh, J., Murray, G. D., Butcher, I., Duncan, R., Smith, S., & Carson, A. J. (2011) · Neurology · doi:10.1212/wnl.0b013e318228c0c7 · Cited by 213
The causalgia—dystonia syndrome
Bhatia, K. P., Bhatt, M. H., & MARSDEN, C. D. (1993) · Brain · doi:10.1093/brain/116.4.843 · Cited by 208
Self-citationPsychopathology and psychogenic movement disorders
Kranick, S. M., Ekanayake, V., Martinez, V., Ameli, R., Hallett, M., & Voon, V. (2011) · Movement Disorders · doi:10.1002/mds.23830 · Cited by 207
Obeso, J. A., Rothwell, J. C., & MARSDEN, C. D. (1981) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.44.8.735 · Cited by 183
Functional movement disorders: Successful treatment with a physical therapy rehabilitation protocol
LaFaver, K., Thompson, J. M., Seime, R. J., Geda, Y. E., Duffy, J. R., & Ahlskog, J. E. (2011) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2011.10.011 · Cited by 182
Abnormal sensorimotor plasticity in organic but not in psychogenic dystonia
Quartarone, A., Rizzo, V., Terranova, C., Morgante, F., Schneider, S. A., Ibrahim, N. M., Girlanda, P., Bhatia, K. P., & Rothwell, J. C. (2009) · Brain · doi:10.1093/brain/awp213 · Cited by 182
Self-citationBelieving is perceiving: mismatch between self-report and actigraphy in psychogenic tremor
Pareés, I., Saifee, T. A., Kassavetis, P., Kojović, M., Rubio‐Agusti, I., Rothwell, J. C., Bhatia, K. P., & Edwards, M. J. (2011) · Brain · doi:10.1093/brain/awr292 · Cited by 178
Self-citationThe cost of somatisation among the working-age population in England for the year 2008-2009.
(2010) · PubMed Central · Cited by 174
Antidepressant Treatment Outcomes of Psychogenic Movement Disorder
Voon, V., & Lang, A. E. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n1206 · Cited by 163
Espay, A. J., Goldenhar, L. M., Voon, V., Schrag, A. E., Burton, N., & Lang, A. E. (2009) · Movement Disorders · doi:10.1002/mds.22618 · Cited by 160
Hysteria — a neurologist's view
MARSDEN, C. D. (1986) · Psychological Medicine · doi:10.1017/s0033291700009090 · Cited by 157
Anderson, K. E., Gruber‐Baldini, A. L., Vaughan, C. G., Reich, S. G., Fishman, P. S., Weiner, W. J., & Shulman, L. M. (2007) · Movement Disorders · doi:10.1002/mds.21687 · Cited by 152
How to identify psychogenic disorders of stance and gait
Lempert, T., Brandt, T. H., Dieterich, M., & Huppert, D. (1991) · Journal of Neurology · doi:10.1007/bf00319680 · Cited by 151
Moving toward “laboratory‐supported” criteria for psychogenic tremor
Schwingenschuh, P., Katschnig, P., Seiler, S., Saifee, T. A., Aguirregomozcorta, M., Cordivari, C., Schmidt, R., Rothwell, J. C., Bhatia, K. P., & Edwards, M. J. (2011) · Movement Disorders · doi:10.1002/mds.23922 · Cited by 139
Self-citationElectrophysiological aids to the diagnosis of psychogenic jerks, spasms, and tremor
Brown, P., & Thompson, P. D. (2001) · Movement Disorders · doi:10.1002/mds.1145 · Cited by 136
Psychogenic movement disorders in children: A report of 15 cases and a review of the literature
Schwingenschuh, P., Pont‐Sunyer, C., Surtees, R. A. H., Edwards, M. J., & Bhatia, K. P. (2008) · Movement Disorders · doi:10.1002/mds.22280 · Cited by 133
Self-citationPsychogenic Dystonia: a Review of 18 Cases
Lang, A. E. (1995) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s031716710004021x · Cited by 127
Long-term prognosis of patients with psychogenic movement disorders
Thomas, M., Vuong, K. D., & Jankovic, J. J. (2006) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2006.03.005 · Cited by 126
In the psychiatrist's chair: how neurologists understand conversion disorder
Kanaan, R., Armstrong, D., Barnes, P., & Wessely, S. C. (2009) · Brain · doi:10.1093/brain/awp060 · Cited by 126
Accelerometry to distinguish psychogenic from essential or parkinsonian tremor
Zeuner, K. E., Shoge, R. O., Goldstein, S. R., Dambrosia, J. M., & Hallett, M. (2003) · Neurology · doi:10.1212/01.wnl.0000076183.34915.cd · Cited by 126
Single-blind clinical trial of psychotherapy for treatment of psychogenic movement disorders
Hinson, V. K., Weinstein, S. L., Bernard, B. A., Leurgans, S. E., & Goetz, C. G. (2005) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2005.10.006 · Cited by 120
Cortical excitability is abnormal in patients with the “fixed dystonia” syndrome
Avanzino, L., Martino, D., van de Warrenburg, B. P. C., Schneider, S. A., Abbruzzese, G., Defazio, G., Schrag, A. E., Bhatia, K. P., & Rothwell, J. C. (2008) · Movement Disorders · doi:10.1002/mds.21801 · Cited by 116
Self-citationEvaluation of clinical diagnostic criteria for psychogenic movement disorders
Shill, H. A., & Gerber, P. (2006) · Movement Disorders · doi:10.1002/mds.20921 · Cited by 116
Gait abnormalities in psychogenic movement disorders
Baik, J. S., & Lang, A. E. (2007) · Movement Disorders · doi:10.1002/mds.21283 · Cited by 115
Keane, J. R. (1989) · Neurology · doi:10.1212/wnl.39.4.586 · Cited by 114
Fahn, S., & Williams, D. T. (1988) · PubMed · Cited by 108
Cohort study on somatoform disorders in Parkinson disease and dementia with Lewy bodies
ONOFRJ, M. C., Bonanni, L., Manzoli, L., & Thomas, A. (2010) · Neurology · doi:10.1212/wnl.0b013e3181df09dd · Cited by 105
Intrathecal baclofen for dystonia of complex regional pain syndrome
van Rijn, Munts, A. G., Marinus, J., Voormolen, J. H. C., de Boer, K. S., Teepe‐Twiss, I. M., van Dasselaar, N. T., Delhaas, E. M., & van Hilten, J. J. (2009) · Pain · doi:10.1016/j.pain.2009.01.014 · Cited by 105
Abnormal sense of intention preceding voluntary movement in patients with psychogenic tremor
Edwards, M. J., Moretto, G., Schwingenschuh, P., Katschnig, P., Bhatia, K. P., & Haggard, P. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.05.021 · Cited by 101
Self-citationPsychogenic movement disorders: A crisis for neurology
Hallett, M. (2006) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-006-0015-x · Cited by 94
Distinguishing psychogenic and essential tremor
Kenney, C., Diamond, A. L., Mejia, N. I., Davidson, A. L., Hunter, C., & Jankovic, J. J. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2007.06.008 · Cited by 91
Psychogenic Tremor: Long-Term Outcome
Jankovic, J. J., Vuong, K. D., & Thomas, M. (2006) · CNS Spectrums · doi:10.1017/s1092852900013535 · Cited by 82
Benaderette, S., Zanotti‐Fregonara, P., Apartis, E., Nguyen, C., Trocello, J., Rémy, P., Devaux, J., Askienazy, S., & Vidailhet, M. (2005) · Movement Disorders · doi:10.1002/mds.20720 · Cited by 82
Axial jerks: a clinical spectrum ranging from propriospinal to psychogenic myoclonus
der Salm, S. M. A. V., Koelman, J. H. T. M., Henneke, S., van Rootselaar, A., & Tijssen, M. A. J. (2010) · Journal of Neurology · doi:10.1007/s00415-010-5531-6 · Cited by 77
Psychogenic dyskinesias in patients with organic movement disorders
Ranawaya, R., Riley, D. E., & Lang, A. E. (1990) · Movement Disorders · doi:10.1002/mds.870050206 · Cited by 76
Movement Disorders on YouTube — Caveat Spectator
Stamelou, M., Edwards, M. J., Espay, A. J., Fung, V. S. C., Hallett, M., Lang, A. E., Tijssen, M. A. J., & Bhatia, K. P. (2011) · New England Journal of Medicine · doi:10.1056/nejmc1107673 · Cited by 75
Self-citationThe effects of physical activity on psychogenic movement disorders
Dallocchio, C., Arbasino, C., Klersy, C., & Marchioni, E. (2010) · Movement Disorders · doi:10.1002/mds.22952 · Cited by 75
Transient arrest of psychogenic tremor induced by contralateral ballistic movements
Kumru, H., Valls‐Solé, J., Valldeoriola, F., Martı́, M. J., Sanegre, M. T., & TOLOSA, E. S. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.08.009 · Cited by 68
Esposito, M., Edwards, M. J., Bhatia, K., Brown, P., & Cordivari, C. (2009) · Movement Disorders · doi:10.1002/mds.22812 · Cited by 63
Self-citationThe treatment of psychogenic movement disorders with suggestion is ethically justified
Shamy, M. C. F. (2010) · Movement Disorders · doi:10.1002/mds.22911 · Cited by 61
Attention to self in psychogenic tremor
van Poppelen, D., Saifee, T. A., Schwingenschuh, P., Katschnig, P., Bhatia, K. P., Tijssen, M. A. J., & Edwards, M. J. (2011) · Movement Disorders · doi:10.1002/mds.23911 · Cited by 61
Self-citationDiagnostic agreement in patients with psychogenic movement disorders
Morgante, F., Edwards, M. J., Espay, A. J., Fasano, A. A., Mir, P., Martino, D., & on behalf of the DISMOV‐SIN study group on psychogenic movement disorders (2012) · Movement Disorders · doi:10.1002/mds.24903 · Cited by 60
Self-citationHow “psychogenic” are psychogenic movement disorders?
Stone, J., & Edwards, M. J. (2011) · Movement Disorders · doi:10.1002/mds.23882 · Cited by 59
Self-citationWhat should we say to patients with symptoms unexplained by disease
Stone, J., Wojcik, W., Durrance, D. Y., Carson, A. J., Lewis, S. C., MacKenzie, L., Warlow, C. P., & Sharpe, M. (2002) · Cited by 55
Immediate response to botulinum toxin injections in patients with fixed dystonia
Edwards, M. J., Bhatia, K. P., & Cordivari, C. (2011) · Movement Disorders · doi:10.1002/mds.23562 · Cited by 55
Self-citationTrimble, M. (1982) · BMJ · doi:10.1136/bmj.285.6357.1768 · Cited by 50
Limb amputations in fixed dystonia: A form of body integrity identity disorder?
Edwards, M. J., Cánovas, A. A., Schrag, A. E., Bloem, B. R., Thompson, P. D., & Bhatia, K. P. (2011) · Movement Disorders · doi:10.1002/mds.23671 · Cited by 49
Self-citationMental rotation of body parts and sensory temporal discrimination in fixed dystonia
Katschnig, P., Edwards, M. J., Schwingenschuh, P., Aguirregomozcorta, M., Kägi, G., Rothwell, J. C., & Bhatia, K. P. (2010) · Movement Disorders · doi:10.1002/mds.23047 · Cited by 36
Self-citationDual task interference in psychogenic tremor
Kumru, H., Begeman, M., TOLOSA, E. S., & Valls‐Solé, J. (2007) · Movement Disorders · doi:10.1002/mds.21670 · Cited by 31
Der Einsatz der transkraniellen Magnetstimulation beim psychogenen Tremor - eine Pilotstudie
Dafotakis, M., Ameli, M., Vitinius, F., Weber, R. A., Albus, C., Fink, G. R., & Nowak, D. A. (2011) · Fortschritte der Neurologie · Psychiatrie · doi:10.1055/s-0029-1246094 · Cited by 26
Identifying patterns of psychogenic gait by video-recording
Jordbru, A., Smedstad, L. M., Moen, V. P., & Martinsen, E. W. (2012) · Journal of Rehabilitation Medicine · doi:10.2340/16501977-0888 · Cited by 23
Bereitschaftspotential in tic disorders: a preliminary observation.
Duggal, H. S., & Nizamie, S. H. (2002) · PubMed · Cited by 21
Diagnosing psychogenic movement disorders—which criteria should be used in clinical practice?
Voon, V., Lang, A. E., & Hallett, M. (2007) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0408 · Cited by 18
Psychopathology and Psychogenic Movement Disorders
Kranick, S. M., Ekanayake, V., & Martinez, V. (2012) · Medical Entomology and Zoology · Cited by 7
Dystonia: a clinical approach.
Edwards, M. J. (2008) · PubMed · Cited by 5
Self-citationDas, S. K., Chowdhury, S., & Sen, A. (2009) · Jaypee Brothers Medical Publishers (P) Ltd. eBooks · doi:10.5005/jp/books/10538_20 · Cited by 2
Cited by
Sorted by citations
Physiotherapy for functional motor disorders: a consensus recommendation
Nielsen, G., Stone, J., Matthews, A., Brown, M., Sparkes, C., Farmer, R., Masterton, L., Duncan, L., Winters, A., Daniell, L., et al. (2014) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2014-309255 · Cited by 427
Self-citationThe prognosis of functional (psychogenic) motor symptoms: a systematic review
Gelauff, J., Stone, J., Edwards, M., & Carson, A. (2014) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2013-305321 · Cited by 368
Self-citationStructure and neural mechanisms of catatonia
Walther, S., Stegmayer, K., Wilson, J. E., & Heckers, S. (2019) · The Lancet Psychiatry · doi:10.1016/s2215-0366(18)30474-7 · Cited by 331
Loss of sensory attenuation in patients with functional (psychogenic) movement disorders
Pareés, I., Brown, H., Nuruki, A., Adams, R. A., Davare, M., Bhatia, K. P., Friston, K., & Edwards, M. J. (2014) · Brain · doi:10.1093/brain/awu237 · Cited by 155
“Secondly, most patients in our sample suffered from functional fixed dystonia, which is the second most common FMD (Edwards and Bhatia, 2012).”
BackgroundSelf-citationPathogenesis and pathophysiology of functional (psychogenic) movement disorders
Baizabal-Carvallo, J. F., Hallett, M., & Jankovic, J. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.02.013 · Cited by 163
Metadata
- Authors
- Edwards, M. J., & Bhatia, K. P.
- Affiliations
- UCL Queen Square Institute of Neurology (GB)
- Corresponding author
- Bhatia, Kailash P
- Venue
- The Lancet Neurology
- Publisher
- Elsevier BV
- Published
- 2012-03
- Volume
- 11
- Issue
- 3
- Pages
- 250-260
- ISSN
- 1474-4422 (ISSN-L)
- OpenAlex
- W2103595952
- Cited by
- 314
- References
- 74
- Citations by year
- 2026: 16 · 2025: 26 · 2024: 12 · 2023: 23 · 2022: 36 · 2021: 19 · 2020: 30 · 2019: 21 · 2018: 19 · 2017: 19 · 2016: 24 · 2015: 17 · 2014: 24 · 2013: 19 · 2012: 8
- FWCI
- 2.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet Neurology (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- National Institute for Health and Care Research
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Keywords
- functional movement disorders, psychogenic movement disorders, conversion disorder, pathophysiology, feigned illness, psychological trauma, diagnosis, treatment, mind-brain relationship, psychological factors
- MeSH terms
- Brain, Humans, Movement Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review