The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
A community-based, controlled study of the epidemiology and pathophysiology of dyspepsia
Open accessAbstract
Background & aims Dyspepsia is common in clinical practice and in the community. The relationship of the symptoms to meals and the pathophysiology in community dyspeptic patients is unclear. The purpose of this study was to measure symptoms, demographic features, and gastric motor and sensory functions associated with dyspepsia in the community.Methods A Modified Bowel Disease Questionnaire was mailed to a random sample of Olmsted County, MN, residents. Dyspeptic patients and healthy controls identified among community respondents completed further questionnaires, Helicobacter pylori serology, gastric emptying by scintigraphy, gastric accommodation by 99mTc-single-photon emission computed tomography imaging, and postprandial symptoms and satiation by a nutrient drink test.Results A total of 34.1% of community respondents reported dyspepsia within the past year, frequent (at least 25% of the time in the past year) in 17.5%, and 18.4% reported meal-related dyspepsia. Dyspepsia was frequent and related to meals in 10.8% of respondents. Compared with nondyspeptic controls, community dyspepsia was associated with higher aggregate symptom scores and bloating after a fully satiating meal. Community dyspepsia also was associated with higher somatization scores (P = .001), reporting of other somatic symptoms (P = .07), and general severity score on the symptom checklist 90 (P = .01), but not with disordered motor or sensory function. Gastric volumes, gastric emptying, and maximum tolerated volumes were not significantly different between community controls and dyspeptic patients.Conclusions Meal-related dyspepsia is an important component of dyspepsia in the community. Community dyspeptic patients have higher symptom scores after a fully satiating meal, consistent with gastric hypersensitivity. This is associated with higher somatization scores rather than disorders of gastric emptying or volumes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“However, we have shown, after a careful review, that there were no systematic differences between individuals who participated and non-participants, including in terms of age, gender, or SSC score in our earlier studies (17,35,36).”
From Psychosocial Distress and Somatic Symptoms in Community Subjects With Irritable Bowel Syndrome: A Psychological Component Is the Rule (2009) · cites this paper as [35]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Initial management strategies for dyspepsia
Delaney, B. C., Moayyedi, P., & Forman, D. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001961 · Cited by 181
RetractedPharmacological interventions for non-ulcer dyspepsia
Moayyedi, P., Shelly, S., Deeks, J. J., Delaney, B., Innes, M., & Forman, D. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001960.pub3 · Cited by 99
RetractedLocke, G. R., Talley, N. J., Fett, S. L., ZINSMEISTER, A. R., & Melton, L. J. (1997) · Gastroenterology · doi:10.1016/s0016-5085(97)70025-8 · Cited by 2,090
Self-citationHistory of the Rochester Epidemiology Project
Melton, L. J. (1996) · Mayo Clinic Proceedings · doi:10.4065/71.3.266 · Cited by 1,443
Role of impaired gastric accommodation to a meal in functional dyspepsia
Tack, J. F., Piessevaux, H. H., Coulie, B. J., Caenepeel, P., & Janssens, J. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70012-5 · Cited by 1,060
Agréus, L., Svärdsudd, K., Nyrén, O., & Tibblin, G. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90373-9 · Cited by 686
Dyspepsia and dyspepsia subgroups: A population-based study
Talley, N. J., Zinsmeister, A. R., Schleck, C. D., & Melton, L. J. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)90764-p · Cited by 663
Self-citationEpidemiology of colonic symptoms and the irritable bowel syndrome
Talley, N. J., Zinsmeister, A. R., van Dyke, C., & Melton, L. J. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90717-y · Cited by 648
Self-citationSingle photon-emission computed tomography
Holly, T. A., Abbott, B., Al-Mallah, M. H., Calnon, D. A., Cohen, M. C., DiFilippo, F. P., Ficaro, E. P., Freeman, M. R., Hendel, R. C., Jain, D., et al. (2010) · Journal of Nuclear Cardiology · doi:10.1007/s12350-010-9246-y · Cited by 603
Symptoms associated with hypersensitivity to gastric distention in functional dyspepsia
Tack, J. F., Caenepeel, P., Fischler, B., Piessevaux, H. H., & Janssens, J. (2001) · Gastroenterology · doi:10.1053/gast.2001.27180 · Cited by 568
Cited by
Sorted by citations
Functional Gastroduodenal Disorders
Tack, J., Talley, N. J., Camilleri, M., Holtmann, G., Hu, P., Malagelada, J.-R., & Stanghellini, V. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.059 · Cited by 2,418
Self-citationPathophysiology and treatment of functional dyspepsia
Tack, J. F., Bisschops, R., & Sarnelli, G. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.05.030 · Cited by 515
Functional dyspepsia, delayed gastric emptying, and impaired quality of life
Talley, N. J., Locke, G. R., Lahr, B. D., Zinsmeister, A. R., Tougas, G., Ligozio, G., Rojavin, M. A., & Tack, J. F. (2005) · Gut · doi:10.1136/gut.2005.078634 · Cited by 288
Self-citationFunctional dyspepsia—symptoms, definitions and validity of the Rome III criteria
Tack, J. F., & Talley, N. J. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.14 · Cited by 276
Camilleri, M., McKinzie, S., Busciglio, I. A., Low, P. A., Sweetser, S. R., Burton, D. D., Baxter, K. L., Ryks, M. D., & Zinsmeister, A. R. (2008) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2008.02.060 · Cited by 244
Self-citation
Metadata
- Authors
- Castillo, E. J., Camilleri, M., Locke, G. R., Burton, D. D., Stephens, D. A., Geno, D. M., & Zinsmeister, A. R.
- Affiliations
- Mayo Clinic (US)
- Corresponding author
- Camilleri, Michael
- Venue
- Clinical Gastroenterology and Hepatology
- Publisher
- Elsevier BV
- Published
- 2004-11
- Volume
- 2
- Issue
- 11
- Pages
- 985-996
- ISSN
- 1542-3565 (ISSN-L)
- OpenAlex
- W1971118578
- Cited by
- 150
- References
- 40
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 3 · 2022: 4 · 2021: 5 · 2020: 6 · 2019: 4 · 2018: 3 · 2017: 5 · 2016: 5 · 2015: 4 · 2014: 15 · 2013: 9 · 2012: 10
- FWCI
- 7.79
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Gastroenterology and Hepatology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (K24DK002638, R01DK054681)
- National Center for Research Resources (RR-00585, M01RR000585)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Helicobacter pylori-related gastroenterology studies
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Keywords
- dyspepsia, gastric hypersensitivity, gastric emptying, gastric accommodation, gastric motility, bloating, somatization, Helicobacter pylori, community prevalence, symptom severity
- MeSH terms
- Adult, Aged, Dyspepsia, Female, Gastric Emptying, Humans, Male, Middle Aged, Minnesota, Surveys and Questionnaires, Satiation, Body Mass Index, Prevalence, Helicobacter pylori, Helicobacter Infections, Patient Selection, Postprandial Period
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
