Alcohol and illicit drug use in people with diabetes
Abstract
As the prevalence of type 1 and type 2 diabetes increases and population-level patterns of alcohol and illicit drug use evolve, clinicians will continue to encounter people with diabetes whose substance use is affecting health outcomes. Substance use contributes substantially to the population-level prevalence of cardiovascular events, cerebrovascular events, cancers, mental health conditions, road trauma, and domestic violence. Alcohol and drug use also have a measurable effect on diabetes incidence and the development of both acute and chronic diabetes-related complications. In this Review, we examine the effect of alcohol and illicit drug use on people with type 1 or type 2 diabetes. We describe evidence for substance use as a risk factor for new-onset diabetes, prevalence of use in people with diabetes, evidence linking substance use with diabetes-related health outcomes, and evidence on the management of these co-occurring conditions.
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An association between recent recreational cannabis consumption and a more than twofold increased risk of DKA has been reported from countries where cannabis has been legalized.
“An association between recent recreational cannabis consumption and a more than twofold increased risk of DKA has been reported from countries where cannabis has been legalized, possibly related to the emergence of higher potency formulations of cannabis and other synthetic cannabinoids (138).”
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- Authors
- Pastor, A., Conn, J., MacIsaac, R. J., & Bonomo, Y.
- Affiliations
- The University of Melbourne (AU)
- The Royal Melbourne Hospital (AU)
- Corresponding author
- Pastor, Adam
- Venue
- The Lancet Diabetes & Endocrinology
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 8
- Issue
- 3
- Pages
- 239-248
- ISSN
- 2213-8587 (ISSN-L)
- OpenAlex
- W3000372339
- Cited by
- 53
- References
- 9
- Citations by year
- 2026: 7 · 2025: 17 · 2024: 10 · 2023: 5 · 2022: 5 · 2021: 7 · 2020: 1 · 2019: 1
- FWCI
- 3.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet Diabetes & Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- AstraZeneca
- Novo Nordisk
- Bayer
- Servier
- Medtronic
- Sanofi Australia
- Boehringer Ingelheim
- Juvenile Diabetes Research Foundation International
- Rebecca L. Cooper Medical Research Foundation
- National Health and Medical Research Council
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- alcohol consumption, illicit drug use, substance use, type 1 diabetes, type 2 diabetes, new-onset diabetes, diabetes complications, cardiovascular risk, mental health, substance use management, comorbidities
- MeSH terms
- Adult, Aged, Alcohol Drinking, Australia, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Humans, Male, Prognosis, Risk Factors, Smoking, Illicit Drugs, Incidence, Substance-Related Disorders, Diabetes Complications
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