The efficacy of a brief alcohol intervention combined with %CDT feedback in patients being treated for type 2 diabetes and/or hypertension
Abstract
OBJECTIVE: Alcohol biomarkers are being developed to improve a physician's ability to identify and intervene with patients with chronic medical problems adversely affected by heavy alcohol use. This article reports the findings of a brief intervention trial which included feedback to patients of their carbohydrate-deficient transferrin (CDT) test results. METHOD: A pilot study was conducted to test the efficacy of brief clinician advice to reduce alcohol use and improve health status in a sample of 151 patients being treated for Type 2 diabetes and hypertension. The intervention included informing patients of their CDT levels. The patients were randomized to a usual care or brief intervention group. RESULTS: There were no significant differences at baseline between the two groups in alcohol use, CDT levels, addiction rates, age, gender, socioeconomic status or health status measures. Following brief intervention, significant differences were observed in the intervention group in alcohol use and CDT: The proportion of heavy drinkers at the 12-month follow-up compared with baseline decreased from 35.8% to 24.7% in the intervention group, with no change in the control group (p < .044). CDT levels decreased as well from 2.79% to 2.41% (16% change) in the control group and 3.05% to 2.35% (28% change) in the intervention group, with significantly more intervention-group patients reducing their CDT level by at least 25% (p < .006). CONCLUSIONS: The study provides new information suggesting brief intervention, combined with feedback on CDT levels, can reduce alcohol use and %CDT in a sample of primary care patients being treated for Type 2 diabetes and hypertension.
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Efficacy/effectiveness scores ranged from 4.5 to 12.
“Efficacy/effectiveness scores ranged from 4.5 (Beckham 2007;Fleming 2004;Romelsjö 1989) to 12 (Lock 2006).”
From Effectiveness of brief alcohol interventions in primary care populations (2018) · cites this paper as Fleming 2004
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- Authors
- Fleming, M., Brown, R., & Brown, D.
- Affiliations
- University of Wisconsin–Madison (US)
- Venue
- Journal of Studies on Alcohol
- Publisher
- Alcohol Research Documentation, Inc.
- Published
- 2004-09
- Volume
- 65
- Issue
- 5
- Pages
- 631-637
- ISSN
- 0096-882X (ISSN-L)
- 1934-2683
- OpenAlex
- W2004465213
- Cited by
- 63
- References
- 0
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 4 · 2016: 2 · 2015: 2 · 2014: 4 · 2013: 5 · 2012: 3
- FWCI
- 2.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Studies on Alcohol (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01aa008512-04)
- National Institute on Alcohol Abuse and Alcoholism (R01 AA08512-03)
- National Eye Institute
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Keywords
- brief alcohol intervention, carbohydrate-deficient transferrin, alcohol biomarkers, alcohol consumption reduction, heavy drinking, type 2 diabetes, hypertension, patient feedback, primary care patients, alcohol-related health problems
- MeSH terms
- Adult, Alcoholism, Diabetes Mellitus, Type 2, Female, Follow-Up Studies, Humans, Hypertension, Male, Middle Aged, Pilot Projects, Transferrin, Feedback, Psychological
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