Cited by 429Diabetes, Cardiovascular Risks, and LipoproteinsObesity, Physical Activity, DietAdipokines, Inflammation, and Metabolic Diseases

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Ethnicity-specific BMI cutoffs for obesity based on type 2 diabetes risk in England: a population-based cohort study

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Abstract

BACKGROUND: ). METHODS: and complete ethnicity data, were registered with a general practitioner practice in England at any point between Sept 1, 1990, and Dec 1, 2018, and had at least 1 year of follow-up data. Patients with type 2 diabetes were identified by use of a CALIBER phenotyping algorithm. Self-reported ethnicity was collapsed into five main categories. Age-adjusted and sex-adjusted negative binomial regression models, with fractional polynomials for BMI, were fitted with incident type 2 diabetes and ethnicity data. FINDINGS: (26·5-27·0) in Arab populations. INTERPRETATION: Revisions of ethnicity-specific BMI cutoffs are needed to ensure that minority ethnic populations are provided with appropriate clinical surveillance to optimise the prevention, early diagnosis, and timely management of type 2 diabetes. FUNDING: National Institute for Health Research.

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Crossref · 10.1016/s2213-8587(21)00088-7

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Figure 1 Study profile CRPD=Clinical Practice Research Datalink.
Figure 1 Study profile CRPD=Clinical Practice Research Datalink.CC BY · PubMed Central
Figure 2 Age-adjusted and sex-adjusted BMI cutoffs in minority ethnic populations in England equivalent to a BMI cutoff of 30·0 kg/m2 in White populations in relation to type 2 diabetes incidence The incidence of type 2 diabetes for a BMI of 30·0 kg/m2 in the White population can be read off the graph at the intersection of the grey horizontal line and the fitted line for the White population.
Figure 2 Age-adjusted and sex-adjusted BMI cutoffs in minority ethnic populations in England equivalent to a BMI cutoff of 30·0 kg/m2 in White populations in relation to type 2 diabetes incidence The incidence of type 2 diabetes for a BMI of 30·0 kg/m2 in the White population can be read off the graph at the intersection of the grey horizontal line and the fitted line for the White population.CC BY · PubMed Central
Figure 3 Age-adjusted and sex-adjusted BMI cutoffs in minority ethnic subgroups in England equivalent to a BMI cutoff of 30·0 kg/m2 in White populations in relation to type 2 diabetes incidence The incidence of type 2 diabetes for a BMI of 30·0 kg/m2 in the White population can be read off the graph at the intersection of the grey horizontal line and the fitted line for the White population.
Figure 3 Age-adjusted and sex-adjusted BMI cutoffs in minority ethnic subgroups in England equivalent to a BMI cutoff of 30·0 kg/m2 in White populations in relation to type 2 diabetes incidence The incidence of type 2 diabetes for a BMI of 30·0 kg/m2 in the White population can be read off the graph at the intersection of the grey horizontal line and the fitted line for the White population.CC BY · PubMed Central
Figure 4 Age-adjusted and sex-adjusted BMI cutoffs in minority ethnic populations in England equivalent to a BMI cutoff of 25·0 kg/m2 in White populations in relation to type 2 diabetes incidence The incidence of type 2 diabetes for a BMI of 25·0 kg/m2 in the White population can be read off the graph at the intersection of the grey horizontal line and the fitted line for the White population.
Figure 4 Age-adjusted and sex-adjusted BMI cutoffs in minority ethnic populations in England equivalent to a BMI cutoff of 25·0 kg/m2 in White populations in relation to type 2 diabetes incidence The incidence of type 2 diabetes for a BMI of 25·0 kg/m2 in the White population can be read off the graph at the intersection of the grey horizontal line and the fitted line for the White population.CC BY · PubMed Central

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Metadata

Authors
Caleyachetty, R., Barber, T. M., Mohammed, N. I., Cappuccio, F. P., Hardy, R., Mathur, R., Banerjee, A., & Gill, P.
Affiliations
University Hospital Coventry (GB)
Corresponding author
Caleyachetty, Rishi
Venue
The Lancet Diabetes & Endocrinology
Publisher
Elsevier BV
Published
2021-07
Volume
9
Issue
7
Pages
419-426
ISSN
2213-8587 (ISSN-L)
OpenAlex
W3162704165
Cited by
429
References
30
Citations by year
2026: 87 · 2025: 100 · 2024: 82 · 2023: 81 · 2022: 61 · 2021: 18
FWCI
45.46
Type
journal article
Language
en
Update notices
erratum (2021-07-01)
Open access
Locations
  • The Lancet Diabetes & Endocrinology (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Warwick Research Archive Portal (University of Warwick) (acceptedVersion)
  • LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Funders
  • South Asian Health Foundation
  • National Institute for Health Research (PB-PG-1217\u201320038, 20038, PB-PG-1217)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
Keywords
type 2 diabetes, obesity, body mass index, ethnic minorities, Arabs, diabetes risk, diabetes prevention, clinical surveillance
MeSH terms
Adult, Diabetes Mellitus, Type 2, England, Ethnicity, Female, Follow-Up Studies, Humans, Male, Middle Aged, Obesity, Population Surveillance, Risk Factors, Cohort Studies, Body Mass Index, Electronic Health Records

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