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Cited by 284

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Adrenal secretion during major depression in 8- to 16-year-olds, I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation

Goodyer, I. M., Herbert, J., Altham, P. M. E., Pearson, J., Secher, S. M., Shiers, H. M.·1996·Psychological Medicine
DOI 10.1017/s0033291700034644
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Abstract

Synopsis: The association between basal cortisol, dehydroepiandrosterone (DHEA), its sulphate (DHEAS) and major depression was investigated in 8- to 16-year-olds. Eighty-two subjects with major depression, 25 non-depressed psychiatric cases and 40 community controls were systematically assessed for current mental state and hormone levels at 08.00, 12.00 and 20.00 h, assayed from salivary samples collected over a 48 h period. The average mean of the two time points was compared between the three groups. Evening cortisol hypersecretion and morning DHEA hyposecretion were significantly, and independently, associated with major depression. High evening cortisol (> 0·594 ng/ml) and low morning DHEA (< 0·200 ng/ml) identified subgroups of depressives with different types of adrenal hormone dysregulation. The association between high evening cortisol or low morning DHEA and MDD was not affected by either age or gender.

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Citations

Cites

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Research works printed but not linked: 43

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Metadata

Authors
Goodyer, I. M., Herbert, J., Altham, P. M. E., Pearson, J., Secher, S. M., & Shiers, H. M.
Venue
Psychological Medicine
Publisher
Cambridge University Press (CUP)
Published
1996-03
Volume
26
Issue
2
Pages
245-256
ISSN
  • 0033-2917 (ISSN-L)
  • 1469-8978
DOI
10.1017/s0033291700034644
OpenAlex
W2134639622
Cited by
284
References
3
FWCI
5.43
Type
journal article
Language
en
Open access
closed
Licence
www.cambridge.org/core/terms (unspecified, 4878 d)

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CoChat. (2026). Citation check: Adrenal secretion during major depression in 8- to 16-year-olds, I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation. https://app.cochat.ai/papers/10.1017/s0033291700034644
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Goodyer, I. M., Herbert, J., Altham, P. M. E., Pearson, J., Secher, S. M., & Shiers, H. M. (1996). Adrenal secretion during major depression in 8- to 16-year-olds, I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation. Psychological Medicine. https://doi.org/10.1017/s0033291700034644

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.