CoChat
Sign Up
Cited by 295Schizophrenia research and treatmentSubstance Abuse Treatment and OutcomesForensic Toxicology and Drug Analysis

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Pre-morbid characteristics and co-morbidity of methamphetamine users with and without psychosis

CHEN, C.-K., LIN, S.-K., SHAM, P. C., BALL, D., LOH, E.-W., HSIAO, C.-C., CHIANG, Y.-L., REE, S.-C., LEE, C.-H., MURRAY, R. M.·2003·Psychological Medicine
DOI 10.1017/s0033291703008353
Open this paper in CoChat — free account

Abstract

Background. The long-term use of methamphetamine (MAMP) can result in psychosis but it is not clear why some individuals develop psychotic symptoms, while others use MAMP regularly over long periods and remain unscathed. We set out to characterize MAMP users and to examine the relationship of pre-morbid personality, pre-morbid social function and other psychiatric disorders to MAMP psychosis. Method. Four hundred and forty-five amphetamine users were recruited from a psychiatric hospital and a detention centre in Taipei, and were assessed with the Diagnostic Interview for Genetic Studies (DIGS). Their parents were interviewed with the Premorbid Schizoid and Schizotypal Traits (PSST) and the Premorbid Social Adjustment (PSA) schedules. Pre-morbid characteristics and psychiatric co-morbidity were compared between the MAMP users with a lifetime diagnosis of MAMP psychosis and those without. Results. The MAMP users with psychosis presented a clinical picture which mimicked the positive symptoms of schizophrenia: 85% had auditory hallucinations; 71% persecutory delusions; 63% delusions of reference. Compared with their non-psychotic counterparts, these MAMP users were younger at first MAMP use, used larger amounts of MAMP, had a significantly higher mean PSST score, and higher rates of major depressive disorder, alcohol dependence and antisocial personality disorder. Conclusions. Earlier and larger use of MAMP was associated with increased risk of psychosis. Our data are also compatible with the view that pre-morbid schizoid/schizotypal personality predisposes MAMP users to develop psychosis, and that the greater the personality vulnerability, the longer the psychosis will persist.

Overview

Integrity signals

Registry

Crossref · 10.1017/s0033291703008353

Cites

23 of 23 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Cited by

Sorted by citations

See all 295

Related

See all

Metadata

Authors
CHEN, C.-K., LIN, S.-K., SHAM, P. C., BALL, D., LOH, E.-W., HSIAO, C.-C., CHIANG, Y.-L., REE, S.-C., LEE, C.-H., & MURRAY, R. M.
Affiliations
Chang Gung Memorial Hospital (TW)
ORCID
Venue
Psychological Medicine
Publisher
Cambridge University Press (CUP)
Published
2003-10-30
Volume
33
Issue
8
Pages
1407-1414
ISSN
  • 0033-2917 (ISSN-L)
  • 1469-8978
DOI
10.1017/s0033291703008353
OpenAlex
W2108964872
Cited by
295
References
23
Citations by year
2026: 4 · 2025: 6 · 2024: 9 · 2023: 5 · 2022: 8 · 2021: 8 · 2020: 28 · 2019: 14 · 2018: 14 · 2017: 7 · 2016: 13 · 2015: 15 · 2014: 21 · 2013: 19 · 2012: 18
FWCI
5.93
Type
journal article
Language
en
Open access
closed
Licence
www.cambridge.org/core/terms (unspecified)
Locations
  • Psychological Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
  • Research Portal (King's College London) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
Keywords
methamphetamine, amphetamine psychosis, premorbid personality, schizoid personality disorder, schizotypy, psychiatric comorbidity, major depressive disorder, alcoholism, antisocial personality disorder, auditory hallucinations, persecutory delusions, delusions of reference, age at first use, dosage
MeSH terms
Adolescent, Adult, Alcoholism, Central Nervous System Stimulants, Antisocial Personality Disorder, Major Depressive Disorder, Depressive Disorder, Major, Disease Susceptibility, Female, Hospitals, Psychiatric, Humans, Male, Methamphetamine, Personality Assessment, Prisons, Psychiatric Status Rating Scales, Psychoses, Substance-Induced, Risk Factors, Schizoid Personality Disorder, Schizophrenia, Schizophrenic Psychology, Social Adjustment, Taiwan, Comorbidity, Causality, Amphetamine-Related Disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review