Sham, Pak C.

PLINK: a tool set for whole-genome association and population-based linkage analyses.

Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A. R., Bender, D., Maller, J., Sklar, P., de Bakker, P. I. W., Daly, M. J., et al. (2007) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 34,089

Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

Purcell, S., Cherny, S. S., & Sham, P. C. (2003) · Bioinformatics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,057

The support of human genetic evidence for approved drug indications

Nelson, M. R., Tipney, H., Painter, J. L., Shen, J., Nicoletti, P., Shen, Y., Floratos, A., Sham, P. C., Li, M. J., Wang, J., et al. (2015) · Nature Genetics

Genetic Associations and EpidemiologyComputational Drug Discovery Methods

Cited by 1,666

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., et al. (2015) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,303

The Heritability of Bipolar Affective Disorder and the Genetic Relationship to Unipolar Depression

McGuffin, P., Rijsdijk, F., Andrew, M., Sham, P., Katz, R., & Cardno, A. (2003) · Archives of General Psychiatry

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,243

Stress and psychological distress among SARS survivors 1 year after the outbreak

Lee, A. M., Wong, J. G., McAlonan, G. M., Cheung, V., Cheung, C., Sham, P. C., Chu, C.-M., Wong, P.-C., Tsang, K. W., & Chua, S. E. (2007) · The Canadian Journal of Psychiatry

COVID-19 and Mental HealthLong-Term Effects of COVID-19

Cited by 1,195

Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets

Li, M.-X., Yeung, J. M. Y., Cherny, S. S., & Sham, P. C. (2012) · Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 962

The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study

Di Forti, M., Quattrone, D., Freeman, T. P., Tripoli, G., Gayer-Anderson, C., Quigley, H., Rodriguez, V., Jongsma, H. E., Ferraro, L., La Cascia, C., et al. (2019) · The Lancet Psychiatry

Cannabis and Cannabinoid ResearchSchizophrenia research and treatment

Cited by 875

Immediate and Sustained Psychological Impact of an Emerging Infectious Disease Outbreak on Health Care Workers

McAlonan, G. M., Lee, A. M., Cheung, V., Cheung, C., Tsang, K. W., Sham, P. C., Chua, S. E., & Wong, J. G. (2007) · The Canadian Journal of Psychiatry

COVID-19 and Mental HealthHealthcare professionals’ stress and burnout

Cited by 755

Gene–environment interaction analysis of serotonin system markers with adolescent depression

Eley, T. C., Sugden, K., Corsico, A., Gregory, A. M., Sham, P., McGuffin, P., Plomin, R., & Craig, I. W. (2004) · Molecular Psychiatry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 663

Comparative genetic architectures of schizophrenia in East Asian and European populations

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lam, M., Indonesia Schizophrenia Consortium, Genetic REsearch on schizophreniA neTwork-China and the Netherlands (GREAT-CN), Chen, C.-Y., Li, Z., Martin, A. R., Bryois, J., Ma, X., Gaspar, H., et al. (2019) · Nature Genetics

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 655

Statistical power and significance testing in large-scale genetic studies

Sham, P. C., & Purcell, S. M. (2014) · Nature Reviews Genetics

Genetic Associations and EpidemiologyStatistical Methods in Clinical Trials

Cited by 573

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., et al. (2014) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 544

The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., Aneey, R., Franke, B., Gill, M., Ebstein, R., et al. (2006) · Molecular Psychiatry

Attention Deficit Hyperactivity DisorderNeurotransmitter Receptor Influence on Behavior

Cited by 533

A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder

Murray, R. M., Sham, P., Van Os, J., Zanelli, J., Cannon, M., & McDonald, C. (2004) · Schizophrenia Research

Schizophrenia research and treatmentBipolar Disorder and Treatment

Cited by 516

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

The International League Against Epilepsy Consortium on Complex Epilepsies, Abou-Khalil, B., Auce, P., Avbersek, A., Bahlo, M., Balding, D. J., Bast, T., Baum, L., Becker, A. J., Becker, F., et al. (2018) · Nature Communications

Epilepsy research and treatmentGenetic Associations and Epidemiology

Cited by 482

A Twin Study of Genetic Relationships Between Psychotic Symptoms

Cardno, A. G., Rijsdijk, F. V., Sham, P. C., Murray, R. M., & McGuffin, P. (2002) · American Journal of Psychiatry

Schizophrenia research and treatmentBipolar Disorder and Treatment

Cited by 460

International Cooperation to Enable the Diagnosis of All Rare Genetic Diseases

Boycott, K. M., Rath, A., Chong, J. X., Hartley, T., Alkuraya, F. S., Baynam, G., Brookes, A. J., Brudno, M., Carracedo, A., den Dunnen, J. T., et al. (2017) · The American Journal of Human Genetics

Genomics and Rare DiseasesConnective tissue disorders research

Cited by 447

Combined Linkage and Association Sib-Pair Analysis for Quantitative Traits

Fulker, D. W., Cherny, S. S., Sham, P. C., & Hewitt, J. K. (1999) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 443

Association of Genetic Risks for Schizophrenia and Bipolar DisorderWith Specific and Generic Brain Structural Endophenotypes

McDonald, C., Bullmore, E. T., Sham, P. C., Chitnis, X., Wickham, H., Bramon, E., & Murray, R. M. (2004) · Archives of General Psychiatry

Schizophrenia research and treatmentBipolar Disorder and Treatment

Cited by 379

Relapse Prevention in Patients With Bipolar Disorder: Cognitive Therapy Outcome After 2 Years

Lam, D. H., Hayward, P., Watkins, E. R., Wright, K., & Sham, P. (2005) · American Journal of Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 347

Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study

MacCabe, J. H., Lambe, M. P., Cnattingius, S., Sham, P. C., David, A. S., Reichenberg, A., Murray, R. M., & Hultman, C. M. (2010) · British Journal of Psychiatry

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 345

Pre-morbid characteristics and co-morbidity of methamphetamine users with and without psychosis

CHEN, C.-K., LIN, S.-K., SHAM, P. C., BALL, D., LOH, E.-W., HSIAO, C.-C., CHIANG, Y.-L., REE, S.-C., LEE, C.-H., & MURRAY, R. M. (2003) · Psychological Medicine

Schizophrenia research and treatmentSubstance Abuse Treatment and Outcomes

Cited by 295