A hand hygiene intervention to reduce infections in child daycare: a randomized controlled trial
Open accessAbstract
Infections are common in children attending daycare centres (DCCs). We evaluated the effect of a hand hygiene (HH) intervention for caregivers on the incidence of gastrointestinal and respiratory infections in children. The intervention was evaluated in a two-arm cluster randomized controlled trial. Thirty-six DCCs received the intervention including HH products, training sessions, and posters/stickers. Thirty-five control DCCs continued usual practice. Incidence of episodes of diarrhoea and the common cold in children was monitored by parents during 6 months. Using multilevel Poisson regression, incidence rate ratios (IRRs) with 95% confidence intervals (CIs) were obtained. Diarrhoeal incidence was monitored in 545 children for 91 937 days. During follow-up, the incidence was 3·0 episodes per child-year in intervention DCCs vs. 3·4 in control DCCs (IRR 0·90, 95% CI 0·73-1·11). Incidence of the common cold was monitored in 541 children for 91 373 days. During follow-up, the incidence was 8·2 episodes per child-year in intervention DCCs vs. 7·4 in control DCCs (IRR 1·07, 95% CI 0·97-1·19). In this study, no evidence for an effect of the intervention was demonstrated on the incidence of episodes of diarrhoea and the common cold.
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- Authors
- ZOMER, T. P., ERASMUS, V., LOOMAN, C. W., TJON-A-TSIEN, A., VAN BEECK, E. F., DE GRAAF, J. M., VAN BEECK, A. H. E., RICHARDUS, J. H., & VOETEN, H. A. C. M.
- Affiliations
- Erasmus MC (NL)
- GGD Rotterdam-Rijnmond (NL)
- Corresponding author
- ZOMER, T. P.
- Venue
- Epidemiology and Infection
- Publisher
- Cambridge University Press (CUP)
- Published
- 2015-01-08
- Volume
- 143
- Issue
- 12
- Pages
- 2494-2502
- ISSN
- 0950-2688 (ISSN-L)
- 1469-4409
- PMC
- PMC4531476
- OpenAlex
- W2001644926
- Cited by
- 48
- References
- 24
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 4 · 2021: 10 · 2020: 8 · 2019: 4 · 2018: 5 · 2017: 3 · 2016: 1 · 2015: 2
- FWCI
- 6.32
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Epidemiology and Infection (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion, other-oa)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion, other-oa)
- RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
- Funders
- ZonMw
- National Center for Advancing Translational Sciences (L30 TR003000)
- Topics
- Health Sciences › Health Professions › Emergency Medical Services › Pediatric health and respiratory diseases
- Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
- Health Sciences › Nursing › Nutrition and Dietetics › Child Nutrition and Water Access
- Keywords
- hand hygiene, daycare centers, pediatric infection, diarrhea, common cold, respiratory infections, gastrointestinal infections, caregivers, infection control
- MeSH terms
- Child Day Care Centers, Child, Preschool, Common Cold, Diarrhea, Female, Follow-Up Studies, Gastrointestinal Diseases, Humans, Infant, Infant, Newborn, Male, Incidence, Hand Hygiene
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