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Cited by 88Salmonella and Campylobacter epidemiologyAntibiotic Resistance in BacteriaAntibiotic Use and Resistance

Prevalence and antimicrobial resistance of Salmonella serovars isolated from poultry in Ghana

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ANDOH, L. A., DALSGAARD, A., OBIRI-DANSO, K., NEWMAN, M. J., BARCO, L., OLSEN, J. E.·2016·Epidemiology and Infection
DOI 10.1017/s0950268816001126PMC PMC9150280
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Abstract

SUMMARY: Poultry are possible sources of non-typhoidal Salmonella serovars which may cause foodborne human disease. We conducted a cross-sectional study to determine the prevalence of Salmonella serovars in egg-laying hens and broilers at the farm level and their susceptibility to antimicrobials commonly used in the poultry industry in Ghana. Sampling of faeces by a sock method (n= 75), dust (n= 75), feed (n= 10) and drinking water (n= 10) was performed at 75 commercial egg-laying and broiler farms in two regions of Ghana and skin neck (n= 30) at a local slaughterhouse from broilers representing different flocks.Salmonella was detected in 94/200 (47%) samples with an overall flock prevalence of 44·0%. Sixteen different serovars were identified with S. Kentucky (18·1%),S. Nima (12·8%),S. Muenster (10·6%),S. Enteritidis (10·6%) and S. Virchow (9·6 %) the most prevalent types. The predominant phage type of S. Enteritidis was PT1. All strains were susceptible to cefotaxime, ceftazidime and cefoxitin. Fifty-seven (60·6%) strains were resistant to one or more of the remaining nine antimicrobials tested by disk diffusion, of which 23 (40·4%) showed multi-resistance (resistance to ⩾3 classes of antimicrobials). Of the resistant strains (n= 57), the most significant were to nalidixic acid (89·5%), tetracycline (80·7%), ciprofloxacin (64·9%), sulfamethazole (42·1%), trimethoprim (29·8%) and ampicillin (26·3%). All S.Kentucky strains were resistant to more than two antimicrobials and shared common resistance to nalidixic acid or ciprofloxacin and tetracycline, often in combinations with other antimicrobials. PFGE analysis using Xba I of S. Kentucky demonstrated one dominant clone in the country. In conclusion, poultry produced in Ghana has a high prevalence of multi-resistant Salmonella and the common finding of clonal S.Kentucky in the Kumasi area warrants further investigations into the epidemiology of this serovar. There is an urgent need for surveillance and control programmes on Salmonella and use of antimicrobials in the Ghanaian poultry industry to protect the health of consumers.

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  • One animal study reported an MDR prevalence of 40.4% in Salmonella spp.

    “One animal study reported an MDR prevalence of 40.4% in Salmonella spp. [32], while another reported an MDR prevalence of 19.1% in coagulase-negative Staphylococci [47].”

    From A Systematic Review on Antimicrobial Resistance in Ghana from a One Health Perspective (2024) · cites this paper as [32]

    The Antimicrobial resistance section reports 23 multi-resistant strains among 57 resistant Salmonella strains (40.35%, rounded to 40.4%). It explicitly gives the prevalence among all 94 Salmonella strains as 24.5%, so 40.4% is supported only with the resistant-strain denominator. Page numbers are not provided in our copy. (LLM, conf=0.90)

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Authors
ANDOH, L. A., DALSGAARD, A., OBIRI-DANSO, K., NEWMAN, M. J., BARCO, L., & OLSEN, J. E.
Affiliations
  • University of Copenhagen (DK)
  • University of Ghana (GH)
  • Istituto Zooprofilattico Sperimentale delle Venezie (IT)
Corresponding author
OLSEN, J. E.
ORCID
Venue
Epidemiology and Infection
Publisher
Cambridge University Press (CUP)
Published
2016-06-23
Volume
144
Issue
15
Pages
3288-3299
ISSN
  • 0950-2688 (ISSN-L)
  • 1469-4409
DOI
10.1017/s0950268816001126
PMC
PMC9150280
OpenAlex
W2464809818
Cited by
88
References
1
Citations by year
2026: 10 · 2025: 5 · 2024: 11 · 2023: 10 · 2022: 11 · 2021: 13 · 2020: 5 · 2019: 8 · 2018: 8 · 2017: 6
FWCI
9.24
Type
journal article
Language
en
Open access
Licence
www.cambridge.org/core/terms (unspecified)
Locations
  • Epidemiology and Infection (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
Funders
  • University of Ghana
  • Kwame Nkrumah University of Science and Technology
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Salmonella and Campylobacter epidemiology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
  • Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
Keywords
Salmonella serotypes, poultry, antimicrobial resistance, multidrug resistance, Salmonella Kentucky, Salmonella Enteritidis, laying hens, broiler chickens, prevalence, foodborne pathogens, slaughterhouses, nalidixic acid resistance, ciprofloxacin resistance, tetracycline resistance
MeSH terms
Animals, Anti-Bacterial Agents, Chickens, Cross-Sectional Studies, Female, Ghana, Microbial Sensitivity Tests, Poultry Diseases, Salmonella, Salmonella Infections, Animal, Prevalence, Electrophoresis, Gel, Pulsed-Field, Drug Resistance, Multiple, Bacterial, Serogroup

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