Cited by 62Child Abuse and TraumaPosttraumatic Stress Disorder ResearchPsychoanalysis and Psychopathology Research

A longitudinal study of several potential mediators of the relationship between child maltreatment and posttraumatic stress disorder symptoms

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Shenk, Chad E., Putnam, Frank W., Rausch, Joseph R., Peugh, James L., Noll, Jennie G.·2014·Development and Psychopathology

Abstract

Child maltreatment is a reliable predictor of posttraumatic stress disorder (PTSD) symptoms. However, not all maltreated children develop PTSD symptoms, suggesting that additional mediating variables explain how certain maltreated children develop PTSD symptoms and others do not. The current study tested three potential mediators of the relationship between child maltreatment and subsequent PTSD symptoms: (a) respiratory sinus arrhythmia reactivity, (b) cortisol reactivity, and (c) experiential avoidance, or the unwillingness to experience painful private events, such as thoughts and memories. Maltreated (n= 51) and nonmaltreated groups (n= 59) completed a stressor paradigm, a measure of experiential avoidance, and a semistructured interview of PTSD symptoms. One year later, participants were readministered the PTSD symptoms interview. Results of a multiple mediator model showed the set of potential mediators mediated the relationship between child maltreatment and subsequent PTSD symptoms. However, experiential avoidance was the only significant, specific indirect effect, demonstrating that maltreated children avoiding painful private events after the abuse were more likely to develop a range of PTSD symptoms 1 year later. These results highlight the importance of experiential avoidance in the development of PTSD symptoms for maltreated children, and implications for secondary prevention and clinical intervention models are discussed.

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  • In a multiple-mediator model along with autonomic nervous system and HPA dysregulation, experiential avoidance was the more potent predictor of subsequent PTSD symptoms in maltreated children and adolescents.

    “When tested in a multiple-mediator model along with autonomic nervous system and HPA dysregulation, experiential avoidance was the more potent predictor of subsequent PTSD symptoms in maltreated children and adolescents (Shenk et al. 2014).”

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Research works printed but not linked: 49

  1. American Psychiatric Association 2000 Diagnostic and Statisical Manual of Mental Disorders - IV - Text Revision (DSM-IV-TR) Washington, D.C American Psychiatric Press
  2. Bentley T Widom CS 2009 A 30-year follow-up of the effects of child abuse and neglect on obesity in adulthood Obesity 17 1900 1905 10.1038/oby.2009.160 19478789 · DOI
  3. Bremner D Vermetten E Kelley ME 2007 Cortisol, dehydroepiandrosterone, and estradiol measured over 24 hours in women with childhood sexual abuse-related posttraumatic stress disorder Journal of Nervous and Mental Disease 195 919 927 10.1097/NMD.0b013e3181594ca0 18000454 · DOI
  4. Breslau N Wilcox HC Storr CL Lucia VC Anthony JC 2004 Trauma exposure and posttraumatic stress disorder: A study of youths in urban America Journal of Urban Health 81 530 544 10.1093/jurban/jth138 15466836 PMC3455932 · DOI
  5. Carpenter LL Carvalho JP Tyrka AR Wier LM Mello AF Mello MF Anderson GM Wilkinson CW Price LH 2007 Decreased adrenocorticotropic hormone and cortisol responses to stress in healthy adults reporting significant childhood maltreatment Biological Psychiatry 62 1080 1087 10.1016/j.biopsych.2007.05.002 17662255 PMC2094109 · DOI · Paper page
  6. Carrion VG Weems CF Ray RD Glaser B Hessl D Reiss AL 2002 Diurnal salivary cortisol in pediatric posttraumatic stress disorder Biological Psychiatry 51 575 582 11950459
  7. Chrousos GP Gold PW 1992 The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis JAMA 267 1244 1252 1538563
  8. Cicchetti D Blender JA 2004 A multiple-levels-of-analysis approach to the study of developmental processes in maltreated children Proceedings of the National Academy of Sciences (USA) 101 17325 17326 10.1073/pnas.0408033101 PMC536022 15583123 · DOI
  9. Cicchetti D Dawson G 2002 Multiple levels of analysis Development and Psychopathology 14 417 420 doi:10.1017.S0954579402003012 12349866
  10. Cicchetti D Rogosch FA 2001 Diverse patterns of neuroendocrine activity in maltreated children Development and Psychopathology 13 677 693 11523854
  11. Cohen JA Mannarino AP Deblinger E 2006 Treating trauma and traumatic grief in children and adolescents New York, NY Guilford Press
  12. Collishaw S Pickles A Messer J Rutter M Shearer C Maughan B 2007 Resilience to adult psychopathology following childhood maltreatment: Evidence from a community sample Child Abuse & Neglect 31 211 229 10.1016/j.chiabu.2007.02.004 17399786 · DOI · Paper page
  13. Copeland WE Keeler G Angold A Costello EJ 2007 Traumatic events and posttraumatic stress in childhood Archives of General Psychiatry 64 577 584 10.1001/archpsyc.64.5.577 17485609 · DOI
  14. Cuffe SP Addy CL Garrison CZ Waller JL Jackson KL McKeown RE Chilappagari S 1998 Prevalence of PTSD in a community sample of older adolescents Journal of the American Academy of Child & Adolescent Psychiatry 37 147 154 10.1097/00004583-199802000-00006 9473910 · DOI
  15. Dale LP Carroll LE Galen G Hayes JA Webb KW Porges SW 2009 Abuse history is related to autonomic regulation to mild exercise and psychological wellbeing Applied Psychophysiology Biofeedback 34 299 308 10.1007/s10484-009-9111-4 19707870 · DOI · Paper page
  16. De Bellis MD Hooper SR Woolley DP Shenk CE 2010 Demographic, maltreatment, and neurobiological correlates of PTSD symptoms in children and adolescents Journal of Pediatric Psychology 35 570 577 10.1093/jpepsy/jsp116 20008084 PMC2910943 · DOI
  17. El-Sheikh M Harger J Whitson SM 2001 Exposure to interparental conflict and children’s adjustment and physical health: The moderating role of vagal tone Child Development 72 1617 1636 11768136
  18. Foa E Rothbaum B 1998 Treating the trauma of rape: Cognitive-behavioral therapy for PTSD New York, NY Guilford Press
  19. Giaconia RM Reinherz HZ Silverman AB Pakiz B Frost AK Cohen E 1995 Traumas and posttraumatic stress disorder in a community population of older adolescents Journal of the American Academy of Child & Adolescent Psychiatry 34 1369 1380 10.1097/00004583-199510000-00023 7592275 · DOI · Paper page
  20. Gordis EB Feres N Olezeski CL Rabkin AN Trickett PK 2010 Skin conductance reactivity and respiratory sinus arrhythmia among maltreated and comparison youth: Relations with aggressive behavior Journal of Pediatric Psychology 35 547 558 10.1093/jpepsy/jsp113 19995866 PMC2874672 · DOI
  21. Gordis EB Granger DA Susman EJ Trickett PK 2006 Asymmetry between salivary cortisol and alpha-amylase reactivity to stress: Relation to aggressive behavior in adolescents Psychoneuroendocrinology 31 976 987 10.1016/j.psyneuen.2006.05.010 16879926 · DOI
  22. Hayes SC Strosahl KD Wilson KG 1999 Acceptance and commitment therapy: An experiential approach to behavior change New York Guilford Press
  23. Hillis SD Anda RF Felitti VJ Nordenberg D Marchbanks PA 2000 Adverse childhood experiences and sexually transmitted diseases in men and women: A retrospective study Pediatrics 106 E11 10878180
  24. Hopper JW Spinazzola J Simpson WB van der Kolk BA 2006 Preliminary evidence of parasympathetic influence on basal heart rate in posttraumatic stress disorder Journal of Psychosomatic Research 60 83 90 10.1016/j.jpsychores.2005.06.002 16380314 · DOI · Paper page
  25. Ivanova JI Birnbaum HG Chen L Duhig AM Dayoub EJ Kantor ES Schiller MB Phillips GA 2011 Cost of post-traumatic stress disorder vs major depressive disorder among patients covered by medicaid or private insurance American Journal of Managed Care 17 e314 323 21851139
  26. Juster RP Bizik G Picard M Arsenault-Lapierre G Sindi S Trepanier L Marin MF Wan N Sekerovic Z Lord C Fiocco AJ Plusquellec P McEwen BS Lupien SJ 2011 A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development Development and Psychopathology 23 725 776 10.1017/s0954579411000289 21756430 · DOI · Paper page
  27. Keary TA Hughes JW Palmieri PA 2009 Women with posttraumatic stress disorder have larger decreases in heart rate variability during stress tasks International Journal of Psychophysiology 73 257 264 10.1016/j.ijpsycho.2009.04.003 19374925 · DOI
  28. Kessler RC Berglund P Demler O Jin R Merikangas KR Walters EE 2005 Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication Archives of General Psychiatry 62 593 602 10.1001/archpsyc.62.6.593 15939837 · DOI · Paper page
  29. Kiess W Meidert A Dressendorfer RA Schriever K Kessler U Konig A Schwarz HP Strasburger CJ 1995 Salivary cortisol levels throughout childhood and adolescence: Relation with age, pubertal stage, and weight Pediatric Research 37 502 506 7596692
  30. Lansford JE Dodge KA Pettit GS Bates JE Crozier J Kaplow J 2002 A 12-year prospective study of the long-term effects of early child physical maltreatment on psychological, behavioral, and academic problems in adolescence Archives of Pediatrica and Adolescent Medicine 156 824 830 PMC2756659 12144375
  31. Lemieux AM Coe CL 1995 Abuse-related posttraumatic stress disorder: Evidence for chronic neuroendocrine activation in women Psychosomatic Medicine 57 105 115 7792368
  32. Linehan MM 1993 Cognitive-behavioral treatment of borderline personality disorder New York Guilford Press
  33. MacKinnon DP Lockwood CM Williams J 2004 Confidence limits for the indirect effect: Distribution of the product and resampling methods Multivariate Behavioral Research 39 99 128 10.1207/s15327906mbr3901_4 20157642 PMC2821115 · DOI · Paper page
  34. Merikangas KR He JP Burstein M Swanson SA Avenevoli S Cui L Benjet C Georgiades K Swendsen J 2010 Lifetime prevalence of mental disorders in U.S. adolescents: Results from the National Comorbidity Survey Replication--Adolescent Supplement (NCS-A) Journal of the American Academy of Child & Adolescent Psychiatry 49 980 989 10.1016/j.jaac.2010.05.017 20855043 PMC2946114 · DOI · Paper page
  35. Miskovic V Schmidt LA Georgiades K Boyle M MacMillan HL 2009 Stability of resting frontal electroencephalogram (EEG) asymmetry and cardiac vagal tone in adolescent females exposed to child maltreatment Developmental Psychobiology 51 474 487 10.1002/dev.20387 19629997 · DOI
  36. Perez CM Widom CS 1994 Childhood victimization and long-term intellectual and academic outcomes Child Abuse & Neglect 18 617 633 7953902
  37. Plumb JC Orsillo SM Luterek JA 2004 A preliminary test of the role of experiential avoidance in post-event functioning Journal of Behavior Therapy and Experimental Psychiatry 35 245 257 10.1016/j.jbtep.2004.04.011 15262220 · DOI · Paper page
  38. Porges SW 2003 The Polyvagal Theory: Phylogenetic contributions to social behavior Physiology & Behavior 79 503 513 12954445
  39. Porges SW Byrne EA 1992 Research methods for measurement of heart rate and respiration Biological Psychology 34 93 130 1467397
  40. Preacher KJ Hayes AF 2008 Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models Behavior Research Methods 40 879 891 18697684
  41. Pruessner JC Kirschbaum C Meinlschmid G Hellhammer DH 2003 Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change Psychoneuroendocrinology 28 916 931 12892658
  42. Rosenthal MZ Cheavens JS Lynch TR Follette V 2006 Thought suppression mediates the relationship between negative mood and PTSD in sexually assaulted women Journal of Traumatic Stress 19 741 745 10.1002/jts.20162 17075920 · DOI
  43. Sack M Hopper JW Lamprecht F 2004 Low respiratory sinus arrhythmia and prolonged psychophysiological arousal in posttraumatic stress disorder: Heart rate dynamics and individual differences in arousal regulation Biological Psychiatry 55 284 290 14744470
  44. Sahar T Shalev AY Porges SW 2001 Vagal modulation of responses to mental challenge in posttraumatic stress disorder Biological Psychiatry 49 637 643 11297721
  45. Santa Ana EJ Saladin ME Back SE Waldrop AE Spratt EG McRae AL LaRowe SD Timmerman MA Upadhyaya H Brady KT 2006 PTSD and the HPA axis: Differences in response to the cold pressor task among individuals with child vs. adult trauma Psychoneuroendocrinology 31 501 509 10.1016/j.psyneuen.2005.11.009 16413134 · DOI
  46. Scheeringa MS Zeanah CH Myers L Putnam F 2004 Heart period and variability findings in preschool children with posttraumatic stress symptoms Biological Psychiatry 55 685 691 15065300
  47. Shenk CE Putnam FW Noll JG 2012 Experiential avoidance and the relationship between child maltreatment and PTSD symptoms: Preliminary evidence Child Abuse & Neglect 36 118 126 10.1016/j.chiabu.2011.09.012 22398300 PMC3345516 · DOI
  48. Sullivan TP Meese KJ Swan SC Mazure CM Snow DL 2005 Precursors and correlates of women’s violence: Child abuse traumatization victimization of women, avoidance coping, and psychological symptoms Psychology of Women Quarterly 29 290 301 10.1111/j.1471-6402.2005.00223.x · DOI
  49. Yehuda R 2001 Biology of posttraumatic stress disorder Journal of Clinical Psychiatry 62 Suppl 17 41 46 11495096

Cited by

Sorted by citations

Authors
Shenk, C. E., Putnam, F. W., Rausch, J. R., Peugh, J. L., & Noll, J. G.
Affiliations
  • Pennsylvania State University (US)
  • University of North Carolina at Chapel Hill (US)
  • University of Cincinnati (US)
Corresponding author
Shenk, Chad E.
Venue
Development and Psychopathology
Published
2014-01-21
Volume
26
Issue
1
Pages
81-91
ISSN
  • 0954-5794 (ISSN-L)
  • 1469-2198
OpenAlex
W2118675997
Cited by
62
References
29
Citations by year
2026: 2 · 2025: 3 · 2024: 3 · 2023: 2 · 2022: 7 · 2021: 6 · 2020: 6 · 2019: 7 · 2018: 6 · 2017: 3 · 2016: 11 · 2015: 6
FWCI
7.89
Type
journal article
Language
en
Open access
Locations
  • Development and Psychopathology (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
  • UNC Libraries
Funders
  • University of Cincinnati
  • National Institutes of Health (5ul1rr026314-03, UL1TR001425, 1UL1RR026314)
  • National Center for Research Resources (1UL1RR026314, UL1-RR026314)
  • National Center for Advancing Translational Sciences
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD052533)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
child abuse, post-traumatic stress disorder, posttraumatic stress symptoms, experiential avoidance, cortisol response, mediators, secondary prevention
MeSH terms
Adolescent, Child Abuse, Female, Heart Rate, Humans, Hydrocortisone, Hypothalamo-Hypophyseal System, Longitudinal Studies, Pituitary-Adrenal System, Saliva, Stress Disorders, Post-Traumatic, Young Adult

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